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References from Molecular rationale for the impairment of the MexAB-OprM efflux pump by a single mutation in MexA. Local targets link to admitted publications; unresolved targets remain external evidence.
To the G20: incentivising antibacterial research and development
10.1016/s1473-3099(17)30404-8 · 2017 · External reference
New antibiotics for bad bugs: where are we?
10.1186/1476-0711-12-22 · 2013 · External reference
10.1038/nrmicro2693
10.1038/nrmicro2693 · External reference
Antimicrobial resistance: translating political commitment into national action
10.2471/blt.17.191890 · 2017 · External reference
Unresolved reference
External reference
10.1128/cmr.00117-14
10.1128/cmr.00117-14 · External reference
Unresolved reference
2011 · External reference
RND-type drug efflux pumps from Gram-negative bacteria: molecular mechanism and inhibition
2015 · External reference
10.1038/nrmicro3380
10.1038/nrmicro3380 · External reference
10.2217/fmb-2019-0235
10.2217/fmb-2019-0235 · External reference
10.1016/j.ebiom.2019.02.061
10.1016/j.ebiom.2019.02.061 · External reference
Structural and functional diversity of resistance–nodulation–cell division transporters
2020 · External reference
10.1586/eri.13.12
10.1586/eri.13.12 · External reference
10.1021/acs.chemrev.1c00055
10.1021/acs.chemrev.1c00055 · External reference
Tripartite assembly of RND multidrug efflux pumps
2016 · External reference
10.1038/nature13205
10.1038/nature13205 · External reference
10.1016/j.sbi.2015.07.015
10.1016/j.sbi.2015.07.015 · External reference
10.1146/annurev-micro-092412-155718
10.1146/annurev-micro-092412-155718 · External reference
10.14348/molcells.2015.2277
10.14348/molcells.2015.2277 · External reference
An allosteric transport mechanism for the AcrAB-TolC multidrug efflux pump
2017 · External reference
Structural basis of RND-type multidrug exporters
2015 · External reference
Mechanism of coupling drug transport reactions located in two different membranes
2015 · External reference
10.1038/nature01050
10.1038/nature01050 · External reference
10.1038/nature05076
10.1038/nature05076 · External reference
10.1126/science.1131542
10.1126/science.1131542 · External reference
Drug Export Pathway of Multidrug Exporter AcrB Revealed by DARPin Inhibitors
2007 · External reference
10.1016/j.jmb.2009.04.001
10.1016/j.jmb.2009.04.001 · External reference
Bypassing the periplasm: Reconstitution of the AcrAB multidrug efflux pump of Escherichia coli
10.1073/pnas.96.13.7190 · 1999 · External reference
10.1089/10766290260469543 · 2002 · Admitted local publication
10.1128/jb.184.23.6490-6499.2002
10.1128/jb.184.23.6490-6499.2002 · External reference
10.1074/jbc.m114.547794
10.1074/jbc.m114.547794 · External reference
Contributions of the AmpC beta -lactamase and the AcrAB multidrug efflux system in intrinsic resistance of Escherichia coli K-12 to beta -lactams
10.1128/aac.44.5.1387-1390.2000 · 2000 · External reference
10.1128/jb.186.5.1258-1269.2004
10.1128/jb.186.5.1258-1269.2004 · External reference
RND Efflux Pumps: Structural Information Translated into Function and Inhibition Mechanisms
10.2174/15680266113136660220 · 2013 · External reference
10.1016/j.molcel.2008.02.015
10.1016/j.molcel.2008.02.015 · External reference
10.1038/35016007
10.1038/35016007 · External reference
Crystal structure of the membrane fusion protein, MexA, of the multidrug transporter in Pseudomonas aeruginosa
10.1074/jbc.c400164200 · 2004 · External reference
Antibiotic export by MexB multidrug efflux transporter is allosterically controlled by a MexA-OprM chaperone-like complex
10.1038/s41467-020-18770-5 · 2020 · External reference
10.1073/pnas.0400375101
10.1073/pnas.0400375101 · External reference
10.1016/j.str.2005.11.015
10.1016/j.str.2005.11.015 · External reference
10.1038/nature09743
10.1038/nature09743 · External reference
Unresolved reference
2015 · External reference
Structures of the wild-type MexAB–OprM tripartite pump reveal its complex formation and drug efflux mechanism
10.1038/s41467-019-09463-9 · 2019 · External reference
Funnel-like hexameric assembly of the periplasmic adapter protein in the tripartite multidrug efflux pump in gram-negative bacteria
10.1074/jbc.m111.238535 · 2011 · External reference
In vitro transport activity of the fully assembled MexAB-OprM efflux pump from Pseudomonas aeruginosa
2015 · External reference
Kinetic control of TolC recruitment by multidrug efflux complexes
10.1073/pnas.0906601106 · 2009 · External reference
10.1371/journal.pone.0005035
10.1371/journal.pone.0005035 · External reference
Stoichiometry of the MexA-OprM binding, as investigated by blue native gel electrophoresis: General
10.1002/elps.201100541 · 2012 · External reference
Interaction of the MexA and MexB Components of the MexAB-OprM Multidrug Efflux System of Pseudomonas aeruginosa: Identification of MexA Extragenic Suppressors of a T578I Mutation in MexB
10.1128/aac.49.10.4375-4378.2005 · 2005 · External reference
10.1128/jb.00718-07
10.1128/jb.00718-07 · External reference
10.1128/jb.186.10.2973-2983.2004
10.1128/jb.186.10.2973-2983.2004 · External reference
10.1073/pnas.0900693106
10.1073/pnas.0900693106 · External reference
Structure of reconstituted bacterial membrane efflux pump by cryo-electron tomography
10.1016/j.bbamem.2010.06.019 · 2010 · External reference
10.1016/j.tim.2015.01.010
10.1016/j.tim.2015.01.010 · External reference
Flexibility in a Drug Transport Accessory Protein: Molecular Dynamics Simulations of MexA
10.1529/biophysj.105.080010 · 2006 · External reference
Structure-function analysis of the ATP-driven glycolipid efflux pump DevBCA reveals complex organization with TolC/HgdD
10.1016/j.febslet.2013.12.004 · 2014 · External reference
Reviving antibiotics: efflux pump inhibitors that interact with AcrA, a membrane fusion protein of the AcrAB-TolC multidrug efflux pump
10.1021/acsinfecdis.6b00167 · 2017 · External reference
10.4155/fmc.15.173
10.4155/fmc.15.173 · External reference
Dynamics of intact MexAB-OprM efflux pump: Focusing on the MexA-OprM Interface
10.1038/s41598-017-16497-w · 2017 · External reference
Unresolved reference
2016 · External reference
10.1110/ps.062416606
10.1110/ps.062416606 · External reference
10.1002/pro.5560020916
10.1002/pro.5560020916 · External reference
10.1038/356083a0
10.1038/356083a0 · External reference
Unresolved reference
2018 · External reference
10.1021/acs.jctc.5b00255
10.1021/acs.jctc.5b00255 · External reference
10.1063/1.445869
10.1063/1.445869 · External reference
10.1021/jp8001614
10.1021/jp8001614 · External reference
10.1016/0263-7855(96)00018-5
10.1016/0263-7855(96)00018-5 · External reference
10.1016/j.softx.2015.06.001 · Admitted local publication
The MM/PBSA and MM/GBSA methods to estimate ligand-binding affinities
10.1517/17460441.2015.1032936 · 2015 · External reference
10.1021/ct3010485
10.1021/ct3010485 · External reference
10.1007/978-1-62703-658-0_11
10.1007/978-1-62703-658-0_11 · 2014 · External reference
10.1021/ct9005745
10.1021/ct9005745 · External reference
10.1016/j.jmgm.2009.01.006
10.1016/j.jmgm.2009.01.006 · External reference
Conformational dynamics of AcrA govern multidrug efflux pump assembly
10.1021/acsinfecdis.9b00273 · 2019 · External reference
Flexible docking and refinement with a coarse-grained protein model using ATTRACT: Flexible Protein-Protein Docking and Refinement
10.1002/prot.24400 · 2013 · External reference
Protein-protein docking with a reduced protein model accounting for side-chain flexibility
10.1110/ps.0239303 · 2003 · External reference
Accounting for conformational changes during protein–protein docking
10.1016/j.sbi.2010.02.001 · 2010 · External reference
10.1021/jp212221v
10.1021/jp212221v · External reference
10.1074/jbc.m305152200
10.1074/jbc.m305152200 · External reference
Unresolved reference
2009 · External reference
A minimal sequence code for switching protein structure and function
10.1073/pnas.0906408106 · 2009 · External reference
Ensemble docking of multiple protein structures: considering protein structural variations in molecular docking
10.1002/prot.21214 · 2007 · External reference
10.1016/j.chembiol.2011.02.011
10.1016/j.chembiol.2011.02.011 · External reference
10.1016/j.mib.2021.03.009
10.1016/j.mib.2021.03.009 · External reference
Discovery of multidrug efflux pump inhibitors with a novel chemical scaffold
2020 · External reference
