Research graph
References from Compounds targeting GPI biosynthesis or N -glycosylation are active against Plasmodium falciparum. Local targets link to admitted publications; unresolved targets remain external evidence.
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Sugar activation and glycosylation in Plasmodium
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Glycosylphosphatidylinositol anchors of Plasmodium falciparum: molecular characterization and naturally elicited antibody response that may provide immunity to malaria pathogenesis
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Apicomplexan C-Mannosyltransferases Modify Thrombospondin Type I-containing Adhesins of the TRAP Family
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Protein O-fucosylation in Plasmodium falciparum ensures efficient infection of mosquito and vertebrate hosts
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Protein O-Fucosyltransferase 2 Is Not Essential for Plasmodium berghei Development
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The disruption of GDP-fucose de novo biosynthesis suggests the presence of a novel fucose-containing glycoconjugate in Plasmodium asexual blood stages
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Signal transduction in host cells by a glycosylphosphatidylinositol toxin of malaria parasites
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10.1093/glycob/cwj066
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10.1021/cb300235m · External reference
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10.1126/science.aap7847 · 2018 · External reference
In vitro activity of E1210, a novel antifungal, against clinically important yeasts and molds
10.1128/aac.00291-11 · 2011 · External reference
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10.1016/j.carres.2013.12.016 · External reference
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10.1038/s41594-018-0031-y · External reference
10.1006/expr.2001.4616
10.1006/expr.2001.4616 · External reference
Studies on the effect of tunicamycin on erythrocytic stages of Plasmodium falciparum
10.1042/bst020184s · 1992 · External reference
A comparative study of a flow-cytometry-based assessment of in vitro plasmodium falciparum drug sensitivity
10.1186/1475-2875-8-294 · 2009 · External reference
Highly accurate protein structure prediction for the human proteome
10.1038/s41586-021-03828-1 · 2021 · External reference
The N-Acetyl-D-glucosaminylphosphatidylinositol De-N-acetylase of Glycosylphosphatidylinositol Biosynthesis Is a Zinc Metalloenzyme
10.1074/jbc.m502402200 · 2005 · External reference
10.1093/bioinformatics/btt473
10.1093/bioinformatics/btt473 · External reference
10.1038/s41586-021-03819-2
10.1038/s41586-021-03819-2 · External reference
10.1128/aac.00527-07
10.1128/aac.00527-07 · External reference
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10.1371/journal.pbio.3000376 · External reference
10.1371/journal.pbio.1001138
10.1371/journal.pbio.1001138 · External reference
10.1371/journal.ppat.1008316
10.1371/journal.ppat.1008316 · External reference
N-linked glycoproteins are related to schizogony of the intraerythrocytic stage in Plasmodium falciparum
10.1074/jbc.271.24.14452 · 1996 · External reference
10.1016/j.chom.2018.03.007
10.1016/j.chom.2018.03.007 · External reference
Dissecting the Gene Expression, Localization, Membrane Topology, and Function of the Plasmodium falciparum STEVOR Protein Family
10.1128/mbio.01500-19 · 2019 · External reference
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10.1371/journal.pntd.0005791 · External reference
10.1016/j.cell.2014.10.053
10.1016/j.cell.2014.10.053 · External reference
Antibody responses to α-Gal in African children vary with age and site and are associated with malaria protection
10.1038/s41598-018-28325-w · 2018 · External reference
Unveiling the Sugary Secrets of Plasmodium Parasites
10.3389/fmicb.2021.712538 · 2021 · External reference
The Apicomplexa-specific glucosamine-6-phosphate N-acetyltransferase gene family encodes a key enzyme for glycoconjugate synthesis with potential as therapeutic target
10.1038/s41598-018-22441-3 · 2018 · External reference
Plasmodium falciparum apicomplexan-specific glucosamine-6-phosphate n-acetyltransferase is key for amino sugar metabolism and asexual blood stage development
2020 · External reference
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10.1074/jbc.272.10.6428 · External reference
10.1074/mcp.m600035-mcp200
10.1074/mcp.m600035-mcp200 · External reference
Glycosylphosphatidylinositol toxin of Plasmodium induces nitric oxide synthase expression in macrophages and vascular endothelial cells by a protein tyrosine kinase-dependent and protein kinase C-dependent signaling pathway
10.4049/jimmunol.156.5.1897 · 1996 · External reference
10.1074/jbc.m413541200
10.1074/jbc.m413541200 · External reference
P25 and P28 proteins of the malaria ookinete surface have multiple and partially redundant functions
10.1093/emboj/20.15.3975 · 2001 · External reference
10.1084/jem.156.1.20
10.1084/jem.156.1.20 · External reference
Substrate specificity of the Plasmodium falciparum glycosylphosphatidylinositol biosynthetic pathway and inhibition by species-specific suicide substrates
10.1021/bi020351l · 2002 · External reference
10.1016/s0925-4439(99)00058-7
10.1016/s0925-4439(99)00058-7 · External reference
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10.1080/20477724.2018.1442764 · External reference
10.1016/s0169-4758(99)01412-x
10.1016/s0169-4758(99)01412-x · External reference
More on Protein Glycosylation in the Malaria Parasite
10.1016/s0169-4758(99)01584-7 · 2000 · External reference
Proteomics and Glycomics Analyses of N-Glycosylated Structures Involved in Toxoplasma gondii-Host Cell Interactions *
10.1074/mcp.m700391-mcp200 · 2008 · External reference
N-glycans as apical sorting signals in epithelial cells
10.1038/378096a0 · 1995 · External reference
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10.1126/science.781840 · External reference
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10.3390/ph14070638 · External reference
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10.1016/j.ijpddr.2020.07.002 · External reference
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10.1016/j.chembiol.2019.11.009 · External reference
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10.1002/jcc.21256 · External reference
10.1093/nar/gkaa971
10.1093/nar/gkaa971 · External reference
10.1186/1758-2946-4-17
10.1186/1758-2946-4-17 · External reference
10.1093/nar/gkz268
10.1093/nar/gkz268 · External reference
10.1093/nar/gkw1105
10.1093/nar/gkw1105 · External reference
10.1093/nar/gkaa1100
10.1093/nar/gkaa1100 · External reference
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