Research graph
References from Sensor dimer disruption as a new mode of action to block the IRE1-mediated unfolded protein response. Local targets link to admitted publications; unresolved targets remain external evidence.
10.1093/embo-reports/kvf202
10.1093/embo-reports/kvf202 · External reference
10.1111/febs.14608
10.1111/febs.14608 · External reference
Structure and molecular mechanism of ER stress signaling by the unfolded protein response signal activator IRE1
10.3389/fmolb.2019.00011 · 2019 · External reference
10.1016/j.jchemneu.2004.02.006
10.1016/j.jchemneu.2004.02.006 · External reference
10.1126/science.1209038
10.1126/science.1209038 · External reference
10.1073/pnas.1915311117
10.1073/pnas.1915311117 · External reference
10.18632/oncotarget.3864
10.18632/oncotarget.3864 · External reference
10.1096/fj.201801240rr
10.1096/fj.201801240rr · External reference
10.1021/acschembio.9b00482
10.1021/acschembio.9b00482 · External reference
Pharmacological targeting of IRE1 in cancer
10.1016/j.trecan.2020.07.006 · 2020 · External reference
10.1038/s41589-019-0326-2
10.1038/s41589-019-0326-2 · External reference
10.1016/j.semcancer.2015.04.010
10.1016/j.semcancer.2015.04.010 · External reference
Structure and mechanism of action of the hydroxy–aryl–aldehyde class of IRE1 endoribonuclease inhibitors
10.1038/ncomms5202 · 2014 · External reference
10.1096/fj.11-182931
10.1096/fj.11-182931 · External reference
Peptidomimetic-Based identification of FDA-approved compounds inhibiting IRE1 activity
10.1111/febs.15372 · 2020 · External reference
10.1124/mol.115.100917
10.1124/mol.115.100917 · External reference
10.1007/s10822-013-9644-8
10.1007/s10822-013-9644-8 · External reference
10.1002/prot.10613
10.1002/prot.10613 · External reference
10.1016/s0022-2836(02)00470-9
10.1016/s0022-2836(02)00470-9 · External reference
Epik: A software program for PKaprediction and protonation state generation for drug-like molecules
10.1007/s10822-007-9133-z · 2007 · External reference
10.1007/s10822-010-9349-1
10.1007/s10822-010-9349-1 · External reference
10.1021/ja9621760
10.1021/ja9621760 · External reference
10.1021/ct900587b
10.1021/ct900587b · External reference
10.1021/acs.jctc.5b00864
10.1021/acs.jctc.5b00864 · External reference
10.1021/ja00214a001
10.1021/ja00214a001 · External reference
10.1007/978-1-4939-6798-8_14
10.1007/978-1-4939-6798-8_14 · 2017 · External reference
PHASE: A novel approach to pharmacophore modeling and 3D database searching
10.1111/j.1747-0285.2006.00384.x · 2006 · External reference
10.1007/s10822-006-9087-6
10.1007/s10822-006-9087-6 · External reference
Energetic analysis of fragment docking and application to structure-based pharmacophore hypothesis generation
10.1007/s10822-009-9268-1 · 2009 · External reference
10.1021/ci900212v
10.1021/ci900212v · External reference
10.1021/jm051256o
10.1021/jm051256o · External reference
Glide: a new approach for rapid, accurate docking and scoring. 1. Method and assessment of docking accuracy. 1. Method and assessment of docking accuracy
10.1021/jm0306430 · 2004 · External reference
A new approach for rapid, accurate docking and scoring. 2. Enrichment factors in database screening
10.1021/jm030644s · 2004 · External reference
Unresolved reference
2006 · External reference
10.1063/1.445869
10.1063/1.445869 · External reference
Nosé – Hoover Chains : The canonical ensemble via continuous dynamics nose-hoover chains : the canonical ensemble via continuous dynamics
10.1063/1.463940 · 1992 · External reference
Invariant molecular-dynamics approach to structural phase transitions
10.1103/physrevb.44.2358 · 1991 · External reference
10.1074/jbc.m110.199737
10.1074/jbc.m110.199737 · External reference
Phosphoregulation of Ire1 RNase splicing activity
10.1038/ncomms4554 · 2014 · External reference
10.1007/978-1-4939-2522-3_13
10.1007/978-1-4939-2522-3_13 · 2015 · External reference
10.1002/jcc.21372
10.1002/jcc.21372 · External reference
10.1038/s41467-018-08152-3
10.1038/s41467-018-08152-3 · External reference
10.1038/s41467-018-05763-8
10.1038/s41467-018-05763-8 · External reference
10.18632/oncotarget.5827
10.18632/oncotarget.5827 · External reference
10.1038/bcj.2012.26
10.1038/bcj.2012.26 · External reference
10.1182/blood-2011-07-366633
10.1182/blood-2011-07-366633 · External reference
10.1073/pnas.1115623109
10.1073/pnas.1115623109 · External reference
10.1074/jbc.m113.493171
10.1074/jbc.m113.493171 · External reference
10.1016/j.molcel.2010.04.001
10.1016/j.molcel.2010.04.001 · External reference
