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References from Celastrol inhibits the proliferation and migration of MCF-7 cells through the leptin-triggered PI3K/AKT pathway. Local targets link to admitted publications; unresolved targets remain external evidence.
Cancer statistics
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Autophagy mediates leptin-induced migration and ERK activation in breast cancer cells
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Molecular modulators of celastrol as the keystones for its diverse pharmacological activities
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Celastrol strongly inhibits proliferation, migration and cancer stem cell properties through suppression of Pin1 in ovarian cancer cells
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Celastrol suppresses angiogenesis-mediated tumor growth through inhibition of AKT/mammalian target of rapamycin pathway
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Celastrol reduces obesity in MC4R deficiency and stimulates sympathetic nerve activity affecting metabolic and cardiovascular functions
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10.18632/oncotarget.22684
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