Research graph
References from i-Modern: Integrated multi-omics network model identifies potential therapeutic targets in glioma by deep learning with interpretability. Local targets link to admitted publications; unresolved targets remain external evidence.
Incidence trends of adult primary intracerebral tumors in four Nordic countries
10.1002/ijc.11578 · 2004 · External reference
10.1002/cncr.20621
10.1002/cncr.20621 · External reference
Combined modality approach to treatment of malignant gliomas
1988 · External reference
Development of multiple lesions during radiation therapy and chemotherapy in patients with gliomas
10.3171/jns.1986.65.5.0654 · 1986 · External reference
10.1056/nejmoa043330
10.1056/nejmoa043330 · External reference
10.1056/nejmra0708126
10.1056/nejmra0708126 · External reference
10.1016/j.ccr.2009.12.020
10.1016/j.ccr.2009.12.020 · External reference
10.1016/j.ccr.2006.02.019
10.1016/j.ccr.2006.02.019 · External reference
10.1016/j.cell.2013.09.034
10.1016/j.cell.2013.09.034 · External reference
10.1016/j.ccr.2010.03.017
10.1016/j.ccr.2010.03.017 · External reference
10.1126/science.1164382
10.1126/science.1164382 · External reference
10.1007/s00401-013-1156-z
10.1007/s00401-013-1156-z · External reference
The human splicing code reveals new insights into the genetic determinants of disease
10.1126/science.1254806 · 2015 · External reference
Unresolved reference
2015 · External reference
DeepChrome: deep-learning for predicting gene expression from histone modifications
10.1093/bioinformatics/btw427 · 2016 · External reference
10.3390/genes10100807
10.3390/genes10100807 · External reference
DNA methylation markers for pan-cancer prediction by deep learning
10.3390/genes10100778 · 2019 · External reference
Unresolved reference
2014 · External reference
Unresolved reference
2016 · External reference
TCGA-assembler 2: software pipeline for retrieval and processing of TCGA/CPTAC data
10.1093/bioinformatics/btx812 · 2018 · External reference
10.1038/nmeth.2810
10.1038/nmeth.2810 · External reference
Missing value imputation for microarray gene expression data using histone acetylation information
10.1186/1471-2105-9-252 · 2008 · External reference
Deep learning–based multi-omics integration robustly predicts survival in liver cancer
10.1158/1078-0432.ccr-17-0853 · 2018 · External reference
Unresolved reference
External reference
Dropout: a simple way to prevent neural networks from overfitting
2014 · External reference
Unresolved reference
External reference
Automatic early stopping using cross validation: quantifying the criteria
10.1016/s0893-6080(98)00010-0 · 1998 · External reference
A new partitioning around medoids algorithm
10.1080/0094965031000136012 · 2003 · External reference
Deep learning for computational biology
10.15252/msb.20156651 · 2016 · External reference
Illuminating the “black box”: a randomization approach for understanding variable contributions in artificial neural networks
10.1016/s0304-3800(02)00064-9 · 2002 · External reference
10.7150/thno.17886
10.7150/thno.17886 · External reference
Gpx 4 is involved in the proliferation, migration and apoptosis of glioma cells
10.1016/j.prp.2017.04.025 · 2017 · External reference
10.1177/17590914211001218
10.1177/17590914211001218 · External reference
10.1056/nejmoa0808710
10.1056/nejmoa0808710 · External reference
miR-155 regulates glioma cells invasion and chemosensitivity by p38 isforms in vitro
10.1002/jcb.25073 · 2015 · External reference
Low expression of CDHR1 is an independent unfavorable prognostic factor in glioma
10.7150/jca.59948 · 2021 · External reference
The common D302H variant of CASP8 is associated with risk of glioma
10.1158/1055-9965.epi-07-2807 · 2008 · External reference
High expression of MMP9 in glioma affects cell proliferation and is associated with patient survival rates
10.3892/ol.2017.5567 · 2017 · External reference
Targeting iron metabolism in high-grade glioma with 68Ga-citrate PET/MR
2018 · External reference
TP53 and p53 statuses and their clinical impact in diffuse low grade gliomas
2014 · External reference
MiR-221 and miR-222 target PUMA to induce cell survival in glioblastoma
2010 · External reference
Are artificial neural networks black boxes?
10.1109/72.623216 · 1997 · External reference
Somatic chromosomal engineering identifies BCAN-NTRK1 as a potent glioma driver and therapeutic target
2017 · External reference
10.1158/1078-0432.ccr-18-2312
10.1158/1078-0432.ccr-18-2312 · External reference
10.1002/prp2.749
10.1002/prp2.749 · External reference
Long noncoding RNA SPRY4-IT1 is a prognostic factor for poor overall survival and has an oncogenic role in glioma
2016 · External reference
10.1158/1078-0432.ccr-11-3091
10.1158/1078-0432.ccr-11-3091 · External reference
Roles of tristetraprolin in tumorigenesis
10.3390/ijms19113384 · 2018 · External reference
Coiled-coil domain containing 109B is a HIF1α-regulated gene critical for progression of human gliomas
2017 · External reference
Expression of the oligodendroglial lineage-associated markers Olig1 and Olig2 in different types of human gliomas
10.1093/jnen/62.10.1052 · 2003 · External reference
10.1215/15228517-2008-016
10.1215/15228517-2008-016 · External reference
ATP1A1 integrates Akt and ERK signaling via potential interaction with Src to promote growth and survival in glioma stem cells
10.3389/fonc.2019.00320 · 2019 · External reference
Sulforaphane-N-acetyl-cysteine induces autophagy through activation of ERK1/2 in U87MG and U373MG cells
10.1159/000495274 · 2018 · External reference
PPFIBP1 induces glioma cell migration and invasion through FAK/Src/JNK signaling pathway
10.1038/s41419-021-04107-7 · 2021 · External reference
TPM3, a strong prognosis predictor, is involved in malignant progression through MMP family members and EMT-like activators in gliomas
10.1007/s13277-014-1974-1 · 2014 · External reference
MAPT (Tau) expression is a biomarker for an increased rate of survival for low-grade glioma
2019 · External reference
10.1038/s41416-020-0814-x
10.1038/s41416-020-0814-x · External reference
Abnormal expression of circulating and tumor-infiltrating carcinoembryonic antigen-related cell adhesion molecule 1 in patients with glioma
2018 · External reference
R Hess K, Fuller GN, Zhang W: Glioma progression is mediated by an addiction to aberrant IGFBP2 expression and can be blocked using anti-IGFBP2 strategies
10.1002/path.4734 · 2016 · External reference
Wang Md, Li Rc, Xie Wf: Combined elevation of TRIB2 and MAP3K1 indicates poor prognosis and chemoresistance to temozolomide in glioblastoma
10.1111/cns.13197 · 2020 · External reference
MicroRNA-22 represses glioma development via activation of macrophage-mediated innate and adaptive immune responses
10.1038/s41388-022-02236-7 · 2022 · External reference
Chang PM-H, Chao T-Y, Huang T-H: Monospecific antibody targeting of CDH11 inhibits epithelial-to-mesenchymal transition and represses cancer stem cell-like phenotype by up-regulating miR-335 in metastatic breast cancer, in vitro and in vivo
2019 · External reference
