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References from Evolutionary progression of collective mutations in Omicron sub-lineages towards efficient RBD-hACE2: Allosteric communications between and within viral and human proteins. Local targets link to admitted publications; unresolved targets remain external evidence.
COVID-19 infection: emergence, transmission, and characteristics of human coronaviruses
10.1016/j.jare.2020.03.005 · 2020 · External reference
10.1038/s12276-021-00604-z
10.1038/s12276-021-00604-z · External reference
Unresolved reference
External reference
10.1038/s41586-020-2008-3
10.1038/s41586-020-2008-3 · External reference
10.1038/s41586-020-2012-7
10.1038/s41586-020-2012-7 · External reference
10.1038/s41586-020-2180-5
10.1038/s41586-020-2180-5 · External reference
10.1016/j.jiph.2021.06.007
10.1016/j.jiph.2021.06.007 · External reference
10.1056/nejmoa1211721
10.1056/nejmoa1211721 · External reference
Receptor binding, immune escape, and protein stability direct the natural selection of SARS-CoV-2 variants
10.1016/j.jbc.2021.101208 · 2021 · External reference
10.3390/ijms22063060
10.3390/ijms22063060 · External reference
10.1016/j.chom.2021.06.006
10.1016/j.chom.2021.06.006 · External reference
10.1039/d1ra04694b
10.1039/d1ra04694b · External reference
10.1016/j.cell.2021.02.037
10.1016/j.cell.2021.02.037 · External reference
Assignment of epidemiological lineages in an emerging pandemic using the pangolin tool
10.1093/ve/veab064 · 2021 · External reference
10.1056/nejmsr2105280
10.1056/nejmsr2105280 · External reference
10.1038/s41564-021-00932-w
10.1038/s41564-021-00932-w · External reference
Emerging SARS-CoV-2 variants of concern and potential intervention approaches
10.1186/s13054-021-03662-x · 2021 · External reference
10.1002/jmv.27541
10.1002/jmv.27541 · External reference
Emerging vaccine-breakthrough SARS-CoV-2 variants
2021 · External reference
10.1016/j.chom.2021.01.014
10.1016/j.chom.2021.01.014 · External reference
10.1016/j.cell.2021.03.013
10.1016/j.cell.2021.03.013 · External reference
10.1038/s41591-021-01347-0
10.1038/s41591-021-01347-0 · External reference
10.1016/j.cell.2021.03.036
10.1016/j.cell.2021.03.036 · External reference
10.1016/s0092-8674(03)00976-0
10.1016/s0092-8674(03)00976-0 · External reference
10.1016/j.bbrc.2020.02.071
10.1016/j.bbrc.2020.02.071 · External reference
10.1128/jvi.00127-20
10.1128/jvi.00127-20 · External reference
Contributions of human ACE2 and TMPRSS2 in determining host–pathogen interaction of COVID-19
10.1007/s12041-021-01262-w · 2021 · External reference
10.1016/j.bbrc.2020.05.028
10.1016/j.bbrc.2020.05.028 · External reference
10.1038/s41401-020-0485-4
10.1038/s41401-020-0485-4 · External reference
10.1126/science.1116480
10.1126/science.1116480 · External reference
10.1111/j.1742-4658.2005.04756.x
10.1111/j.1742-4658.2005.04756.x · External reference
A novel angiotensin-converting enzyme-related carboxypeptidase (ACE2) converts angiotensin I to angiotensin 1–9
10.1161/01.res.87.5.e1 · 2000 · External reference
ACE2, a new regulator of the renin-angiotensin system
10.1016/j.tem.2004.03.001 · 2004 · External reference
10.1002/path.2162
10.1002/path.2162 · External reference
10.1074/jbc.m311191200
10.1074/jbc.m311191200 · External reference
Angiotensin-converting enzyme-2 (ACE2): comparative modeling of the active site, specificity requirements, and chloride dependence
10.1021/bi035268s · 2003 · External reference
10.1056/nejmoa2029849
10.1056/nejmoa2029849 · External reference
10.1038/s41586-020-2571-7
10.1038/s41586-020-2571-7 · External reference
10.1016/j.scr.2020.102125
10.1016/j.scr.2020.102125 · External reference
10.1038/s41551-020-00660-2
10.1038/s41551-020-00660-2 · External reference
10.1016/j.it.2020.03.007
10.1016/j.it.2020.03.007 · External reference
10.1038/s41586-020-2381-y
10.1038/s41586-020-2381-y · External reference
10.1038/s41467-020-16256-y
10.1038/s41467-020-16256-y · External reference
10.1080/19420862.2020.1854149
10.1080/19420862.2020.1854149 · External reference
10.1016/j.cell.2020.09.049
10.1016/j.cell.2020.09.049 · External reference
10.1038/s41586-020-2179-y
10.1038/s41586-020-2179-y · External reference
10.1126/science.abb2507
10.1126/science.abb2507 · External reference
10.1016/j.celrep.2022.110428
10.1016/j.celrep.2022.110428 · External reference
10.1126/science.abn8652
10.1126/science.abn8652 · External reference
10.1016/j.cell.2022.01.019
10.1016/j.cell.2022.01.019 · External reference
10.1016/j.cell.2021.12.046
10.1016/j.cell.2021.12.046 · External reference
SARS-CoV-2 Omicron variant: Immune escape and vaccine development
10.1002/mco2.126 · 2022 · External reference
Immune escape by SARS-CoV-2 Omicron variant and structural basis of its effective neutralization by a broad neutralizing human antibody VacW-209
2022 · External reference
10.1038/s41586-021-04385-3
10.1038/s41586-021-04385-3 · External reference
10.1038/s41586-021-04389-z
10.1038/s41586-021-04389-z · External reference
10.1016/j.chom.2021.02.003
10.1016/j.chom.2021.02.003 · External reference
10.1038/s41586-020-2852-1
10.1038/s41586-020-2852-1 · External reference
10.7554/elife.61312
10.7554/elife.61312 · External reference
Human serum from SARS-CoV-2-vaccinated and COVID-19 patients shows reduced binding to the RBD of SARS-CoV-2 Omicron variant
10.1186/s12916-022-02312-5 · 2022 · External reference
10.1016/j.cell.2022.01.001
10.1016/j.cell.2022.01.001 · External reference
10.26434/chemrxiv-2021-n23f5
10.26434/chemrxiv-2021-n23f5 · External reference
SARS-CoV-2 Omicron RBD shows weaker binding affinity than the currently dominant Delta variant to human ACE2
2022 · External reference
10.1038/s41586-022-04594-4
10.1038/s41586-022-04594-4 · External reference
Mutational and phylogenetic analyses of the two lineages of the Omicron variant
10.1002/jmv.27558 · 2022 · External reference
10.1101/2022.02.11.480029
10.1101/2022.02.11.480029 · External reference
10.21203/rs.3.rs-1375091/v1
10.21203/rs.3.rs-1375091/v1 · External reference
Emergence of Omicron third lineage BA.3 and its importance
10.1002/jmv.27601 · 2022 · External reference
10.3390/pathogens11010045
10.3390/pathogens11010045 · External reference
10.1021/acs.jproteome.0c00654
10.1021/acs.jproteome.0c00654 · External reference
10.1016/j.compbiomed.2021.104654
10.1016/j.compbiomed.2021.104654 · External reference
Computational analysis of protein stability and allosteric interaction networks in distinct conformational forms of the SARS-CoV-2 spike D614G mutant: reconciling functional mechanisms through allosteric model of spike regulation
2021 · External reference
10.1021/acs.jpclett.1c01415
10.1021/acs.jpclett.1c01415 · External reference
10.1016/j.str.2021.12.011
10.1016/j.str.2021.12.011 · External reference
Computational Insights into the allosteric effect and dynamic structural features of the SARS-COV-2 spike protein
10.1002/chem.202104215 · 2022 · External reference
Deciphering isoniazid drug resistance mechanisms on dimeric mycobacterium tuberculosis KatG via post-molecular dynamics analyses including combined dynamic residue network metrics
2022 · External reference
Allostery and missense mutations as intermittently linked promising aspects of modern computational drug discovery
2022 · External reference
10.1016/j.csbj.2021.10.011 · Admitted local publication
10.1016/j.csbj.2021.11.016 · Admitted local publication
10.2807/1560-7917.es.2017.22.13.30494
10.2807/1560-7917.es.2017.22.13.30494 · External reference
10.46234/ccdcw2021.255
10.46234/ccdcw2021.255 · External reference
Unresolved reference
External reference
10.1093/nar/gkh381
10.1093/nar/gkh381 · External reference
10.21105/joss.03021
10.21105/joss.03021 · External reference
10.1109/mcse.2007.55
10.1109/mcse.2007.55 · External reference
10.1109/mcse.2011.37
10.1109/mcse.2011.37 · External reference
10.1021/ct400341p
10.1021/ct400341p · External reference
10.1016/0263-7855(96)00018-5
10.1016/0263-7855(96)00018-5 · External reference
10.1016/j.csbj.2021.08.043 · Admitted local publication
MD-TASK: a software suite for analyzing molecular dynamics trajectories
10.1093/bioinformatics/btx349 · 2017 · External reference
10.1016/s0006-3495(04)74086-2
10.1016/s0006-3495(04)74086-2 · External reference
10.1021/acs.jcim.7b00630
10.1021/acs.jcim.7b00630 · External reference
Modulation of human Hsp90α conformational dynamics by allosteric ligand interaction at the c-terminal domain
10.1038/s41598-018-35835-0 · 2019 · External reference
10.1093/nar/gkh468
10.1093/nar/gkh468 · External reference
10.1093/nar/gkz397
10.1093/nar/gkz397 · External reference
10.1093/nar/gkt376
10.1093/nar/gkt376 · External reference
Unresolved reference
2022 · External reference
10.1016/s0140-6736(21)02758-6
10.1016/s0140-6736(21)02758-6 · External reference
The pH effects on SARS-CoV and SARS-CoV-2 spike proteins in the process of binding to hACE2
10.3390/pathogens11020238 · 2022 · External reference
10.1016/j.cell.2020.08.012
10.1016/j.cell.2020.08.012 · External reference
10.7554/elife.70658
10.7554/elife.70658 · External reference
10.1016/j.jmb.2019.07.012
10.1016/j.jmb.2019.07.012 · External reference
10.1016/s1074-7613(00)00061-3
10.1016/s1074-7613(00)00061-3 · External reference
10.1073/pnas.1609780113
10.1073/pnas.1609780113 · External reference
10.3390/cells10030506
10.3390/cells10030506 · External reference
10.1093/jb/mvab041
10.1093/jb/mvab041 · External reference
10.1074/jbc.ra120.015303
10.1074/jbc.ra120.015303 · External reference
10.1080/07391102.2020.1802348
10.1080/07391102.2020.1802348 · External reference
10.1074/jbc.m502486200
10.1074/jbc.m502486200 · External reference
Principles of protein-protein interactions
10.1073/pnas.93.1.13 · 1996 · External reference
10.26434/chemrxiv-2021-7thm1
10.26434/chemrxiv-2021-7thm1 · External reference
Betweenness centrality and resistance distance in communication networks
10.1109/mnet.2010.5634437 · 2010 · External reference
10.1140/epjb/e2004-00111-4
10.1140/epjb/e2004-00111-4 · External reference
10.1126/sciadv.abb8097
10.1126/sciadv.abb8097 · External reference
Differential binding of SARS-CoV-2 Spike protein variants to its cognate receptor hACE2 using molecular modeling based binding analysis
2021 · External reference
10.1101/2021.10.27.465996
10.1101/2021.10.27.465996 · External reference
10.3390/molecules26020406
10.3390/molecules26020406 · External reference
In silico screening of bioactive compounds of representative seaweeds to inhibit SARS-CoV-2 ACE2-bound omicron B.1.1.529 spike protein trimer
10.3390/md20020148 · 2022 · External reference
Molecular docking and dynamics studies to explore effective inhibitory peptides against the spike receptor binding domain of SARS-CoV-2
10.3389/fmolb.2021.791642 · 2022 · External reference
10.1002/slct.202101852
10.1002/slct.202101852 · External reference
Identification of potential natural inhibitors of the receptor-binding domain of the SARS-CoV-2 spike protein using a computational docking approach
10.5339/qmj.2021.12 · 2021 · External reference
10.1016/j.jaim.2020.05.009
10.1016/j.jaim.2020.05.009 · External reference
10.1080/07391102.2020.1837676
10.1080/07391102.2020.1837676 · External reference
10.1021/acsnano.0c04674
10.1021/acsnano.0c04674 · External reference
10.1002/jcp.30367
10.1002/jcp.30367 · External reference
10.7554/elife.69091
10.7554/elife.69091 · External reference
10.1002/1873-3468.14076
10.1002/1873-3468.14076 · External reference
Laplacian centrality: a new centrality measure for weighted networks
10.1016/j.ins.2011.12.027 · 2012 · External reference
10.3390/v12050497
10.3390/v12050497 · External reference
10.1126/science.abb2762
10.1126/science.abb2762 · External reference
10.1101/2021.12.14.472585
10.1101/2021.12.14.472585 · External reference
Comprehensive mapping of binding hot spots of SARS-CoV-2 RBD-specific neutralizing antibodies for tracking immune escape variants
10.1186/s13073-021-00985-w · 2021 · External reference
10.1371/journal.pcbi.1008790
10.1371/journal.pcbi.1008790 · External reference
10.1007/s00249-019-01384-1
10.1007/s00249-019-01384-1 · External reference
10.1038/s41586-021-04245-0
10.1038/s41586-021-04245-0 · External reference
10.1016/j.bbrc.2021.12.079
10.1016/j.bbrc.2021.12.079 · External reference
10.1101/2022.01.24.477633
10.1101/2022.01.24.477633 · External reference
E484K and N501Y SARS-CoV 2 spike mutants Increase ACE2 recognition but reduce affinity for neutralizing antibody
10.1016/j.intimp.2021.108424 · 2022 · External reference
