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References from Mechanisms of antibiotic action shape the fitness landscapes of resistance mutations. Local targets link to admitted publications; unresolved targets remain external evidence.
Unresolved reference
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Unresolved reference
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10.1377/hlthaff.2017.1153
10.1377/hlthaff.2017.1153 · External reference
Unresolved reference
External reference
Antibiotic resistance–what's dosing got to do with it?
10.1097/ccm.0b013e318180fe62 · 2008 · External reference
10.1128/cmr.00030-10
10.1128/cmr.00030-10 · External reference
Risk Factors for the Spread of Antibiotic-Resistant Bacteria
10.2165/00003495-199855030-00001 · 1998 · External reference
Selection and evolution of resistance to antimicrobial drugs
10.1002/iub.1278 · 2014 · External reference
Determination of minimum inhibitory concentrations
10.1093/jac/48.suppl_1.5 · 2001 · External reference
10.1038/nrmicro2319
10.1038/nrmicro2319 · External reference
10.1111/eva.12196
10.1111/eva.12196 · External reference
10.1111/eva.12202
10.1111/eva.12202 · External reference
10.1038/emboj.2009.17
10.1038/emboj.2009.17 · External reference
Studies on streptomycin-dependent bacteria: Effect of streptomycin on protein synthesis by streptomycin-sensitive, streptomycin-resistant and streptomycin-dependent, mutants of Escherichia coli, Biochimica et Biophysica Acta (BBA)
1964 · External reference
10.1086/511642
10.1086/511642 · External reference
10.1371/journal.ppat.1002158
10.1371/journal.ppat.1002158 · External reference
Predicting drug resistance evolution: insights from antimicrobial peptides and antibiotics
2018 · External reference
The mutant selection window in rabbits infected with Staphylococcus aureus
10.1086/508752 · 2006 · External reference
A pharmacokinetic/pharmacodynamic model developed for the effect of colistin on Pseudomonas aeruginosa in vitro with evaluation of population pharmacokinetic variability on simulated bacterial killing
10.1093/jac/dkt520 · 2014 · External reference
10.1046/j.1365-2958.2002.03173.x
10.1046/j.1365-2958.2002.03173.x · External reference
10.1038/s41559-017-0243-2
10.1038/s41559-017-0243-2 · External reference
Compensatory mutations, antibiotic resistance and the population genetics of adaptive evolution in bacteria
10.1093/genetics/154.3.985 · 2000 · External reference
10.1016/j.tim.2018.01.005
10.1016/j.tim.2018.01.005 · External reference
10.1371/journal.pcbi.0020137
10.1371/journal.pcbi.0020137 · External reference
10.7554/elife.38200
10.7554/elife.38200 · External reference
Substitution at rt269 in Hepatitis B Virus Polymerase Is a Compensatory Mutation Associated with Multi-Drug Resistance
2015 · External reference
Development of glycopeptide-intermediate resistance by Staphylococcus aureus leads to attenuated infectivity in a rat model of endocarditis
10.1016/j.micpath.2008.09.003 · 2008 · External reference
10.1016/j.micinf.2005.12.031
10.1016/j.micinf.2005.12.031 · External reference
10.1038/nrmicro3380
10.1038/nrmicro3380 · External reference
10.1038/s41559-021-01397-0
10.1038/s41559-021-01397-0 · External reference
10.3201/eid0901.020172
10.3201/eid0901.020172 · External reference
10.1371/journal.pbio.2005056
10.1371/journal.pbio.2005056 · External reference
10.1128/aac.48.10.3670-3676.2004
10.1128/aac.48.10.3670-3676.2004 · External reference
Abel zur Wiesch, Drug-target binding quantitatively predicts optimal antibiotic dose levels in quinolones
10.1371/journal.pcbi.1008106 · 2020 · External reference
10.1126/scitranslmed.aaa8760
10.1126/scitranslmed.aaa8760 · External reference
10.1128/aac.40.10.2380
10.1128/aac.40.10.2380 · External reference
Two Novel Point Mutations in Clinical Staphylococcus aureus Reduce Linezolid Susceptibility and Switch on the Stringent Response to Promote Persistent Infection
10.1371/journal.ppat.1000944 · 2010 · External reference
Whole genome analysis of linezolid resistance in Streptococcus pneumoniae reveals resistance and compensatory mutations
10.1186/1471-2164-12-512 · 2011 · External reference
A Naturally Occurring Gene Amplification Leading to Sulfonamide and Trimethoprim Resistance in Streptococcus agalactiae
10.1128/jb.01357-07 · 2008 · External reference
10.1038/ncomms5296
10.1038/ncomms5296 · External reference
Nonoptimal Gene Expression Creates Latent Potential for Antibiotic Resistance
2018 · External reference
10.1128/aac.49.6.2343-2351.2005
10.1128/aac.49.6.2343-2351.2005 · External reference
Quinolone-mediated bacterial death
10.1128/aac.01617-06 · 2008 · External reference
Quantitative analysis of the Escherichia coli proteome
10.1016/j.dib.2014.08.004 · 2014 · External reference
10.1111/j.1574-6976.2008.00105.x
10.1111/j.1574-6976.2008.00105.x · External reference
Acyltransferase activities of the high-molecular-mass essential penicillin-binding proteins
10.1042/bj2790601 · 1991 · External reference
10.1128/jb.178.21.6110-6115.1996
10.1128/jb.178.21.6110-6115.1996 · External reference
10.1007/0-306-48056-5_10
10.1007/0-306-48056-5_10 · 2003 · External reference
10.1371/journal.pgen.1000760
10.1371/journal.pgen.1000760 · External reference
Mechanisms of bacterial persistence during stress and antibiotic exposure
10.1126/science.aaf4268 · 2016 · External reference
10.1016/j.cub.2010.04.045
10.1016/j.cub.2010.04.045 · External reference
10.1128/aac.01460-09
10.1128/aac.01460-09 · External reference
10.1128/aac.44.7.1771-1777.2000
10.1128/aac.44.7.1771-1777.2000 · External reference
10.1126/science.1124410
10.1126/science.1124410 · External reference
Mechanism-based pharmacokinetic-pharmacodynamic modeling of antimicrobial drug effects
10.1007/s10928-007-9069-x · 2007 · External reference
Conformational changes in DNA gyrase revealed by limited proteolysis
10.1074/jbc.273.35.22606 · 1998 · External reference
Mechanism of inhibition of DNA gyrase by analogues of nalidixic acid: The target of the drugs is DNA
10.1073/pnas.82.2.307 · 1985 · External reference
Unresolved reference
1990 · External reference
10.1007/978-1-4757-9203-4
10.1007/978-1-4757-9203-4 · External reference
The DNA gyrase-quinolone complex. ATP hydrolysis and the mechanism of DNA cleavage
10.1074/jbc.273.35.22615 · 1998 · External reference
10.1128/aac.02463-14
10.1128/aac.02463-14 · External reference
10.1046/j.1365-2958.1999.01612.x
10.1046/j.1365-2958.1999.01612.x · External reference
10.1016/s1369-5274(99)00008-9
10.1016/s1369-5274(99)00008-9 · External reference
Bacteriostatic versus bactericidal activity of ciprofloxacin in Escherichia coli assessed by flow cytometry using a novel far-red dye
10.1038/ja.2011.5 · 2011 · External reference
Clinical Relevance of Bacteriostatic versus Bactericidal Mechanisms of Action in the Treatment of Gram-Positive Bacterial Infections
10.1086/381972 · 2004 · External reference
Bacteriostatic versus bactericidal antibiotics for patients with serious bacterial infections: systematic review and meta-analysis
10.1093/jac/dku379 · 2015 · External reference
10.1126/science.287.5457.1479
10.1126/science.287.5457.1479 · External reference
10.1016/j.tim.2014.04.007
10.1016/j.tim.2014.04.007 · External reference
Quinolone resistance mutations in Streptococcus pneumoniae GyrA and ParC proteins: mechanistic insights into quinolone action from enzymatic analysis, intracellular levels, and phenotypes of wild-type and mutant proteins
10.1128/aac.45.11.3140-3147.2001 · 2001 · External reference
10.1128/aac.01182-12
10.1128/aac.01182-12 · External reference
10.1111/j.1600-0463.2009.02563.x
10.1111/j.1600-0463.2009.02563.x · External reference
10.1111/j.1574-6976.2007.00095.x
10.1111/j.1574-6976.2007.00095.x · External reference
Mechanisms of fluoroquinolone resistance: an update 1994–1998
10.2165/00003495-199958002-00003 · 1999 · External reference
Contributions of the combined effects of topoisomerase mutations toward fluoroquinolone resistance in Escherichia coli
10.1128/aac.00647-07 · 2007 · External reference
Pharmacokinetic-Pharmacodynamic Modeling of Antibacterial Drugs
10.1124/pr.111.005769 · 2013 · External reference
10.1038/nrg3351
10.1038/nrg3351 · External reference
10.1038/nature06847
10.1038/nature06847 · External reference
10.1128/aac.41.2.363
10.1128/aac.41.2.363 · External reference
10.1371/journal.pone.0018327
10.1371/journal.pone.0018327 · External reference
Is selection relevant in the evolutionary emergence of drug resistance?
10.1016/j.tim.2015.01.005 · 2015 · External reference
10.1084/jem.88.1.99
10.1084/jem.88.1.99 · External reference
Drug efflux pump deficiency and drug target resistance masking in growing bacteria
10.1073/pnas.0811514106 · 2009 · External reference
10.7554/elife.55155
10.7554/elife.55155 · External reference
General Principles of Antimicrobial Therapy
10.4065/mcp.2010.0639 · 2011 · External reference
10.1073/pnas.1802233115
10.1073/pnas.1802233115 · External reference
Rapid pathogen-specific phenotypic antibiotic susceptibility testing using digital LAMP quantification in clinical samples
10.1126/scitranslmed.aal3693 · 2017 · External reference
10.1073/pnas.120163297
10.1073/pnas.120163297 · External reference
A New Scaling and Squaring Algorithm for the Matrix Exponential
10.1137/09074721x · 2009 · External reference
An Algorithm for Generalized Matrix Eigenvalue Problems
10.1137/0710024 · 1973 · External reference
Unresolved reference
1995 · External reference
10.1098/rspb.1999.0936
10.1098/rspb.1999.0936 · External reference
