Contact and support
Need help, have a question, or want to contact the ResearchHub team?
© 2026 ResearchHub. Built for responsible scholarly connection.
Privacy-aware community infrastructureResearch graph
References from A disordered region retains the full protease inhibitor activity and the capacity to induce CD8 + T cells in vivo of the oral vaccine adjuvant U-Omp19. Local targets link to admitted publications; unresolved targets remain external evidence.
Mucosal vaccines — fortifying the frontiers
2021 · External reference
10.1038/s41573-021-00163-y
10.1038/s41573-021-00163-y · External reference
10.1016/j.smim.2018.05.001
10.1016/j.smim.2018.05.001 · External reference
10.1016/j.coi.2017.06.005
10.1016/j.coi.2017.06.005 · External reference
U-Omp19 from Brucella abortus increases dmLT immunogenicity and improves protection against Escherichia coli heat-labile toxin (LT) oral challenge
10.1016/j.vaccine.2020.05.039 · 2020 · External reference
U-Omp19 from Brucella abortus Is a Useful Adjuvant for Vaccine Formulations against Salmonella Infection in Mice
10.3389/fimmu.2017.00171 · 2017 · External reference
A bacterial protease inhibitor protects antigens delivered in oral vaccines from digestion while triggering specific mucosal immune responses
10.1016/j.jconrel.2015.10.011 · 2015 · External reference
Brucella abortus Omp19 recombinant protein subcutaneously co-delivered with an antigen enhances antigen-specific T helper 1 memory responses and induces protection against parasite challenge
10.1016/j.vaccine.2015.12.012 · 2016 · External reference
10.4049/jimmunol.1501188
10.4049/jimmunol.1501188 · External reference
The Trypanosoma cruzi TcTASV-C protein subfamily administrated with U-Omp19 promotes a protective response against a lethal challenge in mice
10.1016/j.vaccine.2020.10.006 · 2020 · External reference
10.1016/j.jconrel.2018.11.025
10.1016/j.jconrel.2018.11.025 · External reference
A novel bacterial protease inhibitor adjuvant in RBD-based COVID-19 vaccine formulations containing alum increases neutralizing antibodies, specific germinal center B cells and confers protection against SARS-CoV-2 infection in mice
10.3389/fimmu.2022.844837 · 2022 · External reference
A novel oral rabies vaccine enhances the immunogenicity through increasing dendritic cells activation and germinal center formation by expressing U-OMP19 in a mouse model
10.1080/22221751.2021.1923341 · 2021 · External reference
10.1101/2021.12.07.471590
10.1101/2021.12.07.471590 · External reference
10.1093/nar/gkx1134
10.1093/nar/gkx1134 · External reference
Protease inhibitors in the clinic
10.2174/1573406053402569 · 2005 · External reference
Omp19 enables Brucella abortus to evade the antimicrobial activity from host's proteolytic defense system
10.3389/fimmu.2019.01436 · 2019 · External reference
Stability studies of the vaccine adjuvant U-Omp19
10.1016/j.xphs.2020.10.011 · 2021 · External reference
10.1002/pro.368
10.1002/pro.368 · External reference
10.1093/protein/14.12.993
10.1093/protein/14.12.993 · External reference
ExPASy: SIB bioinformatics resource portal
10.1093/nar/gks400 · 2012 · External reference
10.1093/nar/gky497
10.1093/nar/gky497 · External reference
Denaturant m values and heat capacity changes: relation to changes in accessible surface areas of protein unfolding
10.1002/pro.5560041020 · 1995 · External reference
Protsa. a web application for calculating sequence specific protein solvent accessibilities in the unfolded ensemble
10.1186/1471-2105-10-104 · 2009 · External reference
10.1016/j.bbapap.2010.01.017
10.1016/j.bbapap.2010.01.017 · External reference
10.1107/s0907444909047337
10.1107/s0907444909047337 · External reference
10.1107/s0907444913000061
10.1107/s0907444913000061 · External reference
10.1107/s2059798319011471
10.1107/s2059798319011471 · External reference
10.1107/s090744490705024x
10.1107/s090744490705024x · External reference
10.1107/s0907444910007493
10.1107/s0907444910007493 · External reference
10.1002/pro.3330
10.1002/pro.3330 · External reference
10.1007/bf00197809
10.1007/bf00197809 · External reference
10.1002/prot.20449
10.1002/prot.20449 · External reference
10.1023/a:1008290618449
10.1023/a:1008290618449 · External reference
10.1016/j.jmr.2007.04.002
10.1016/j.jmr.2007.04.002 · External reference
10.1021/bi3001825
10.1021/bi3001825 · External reference
10.1021/ja00381a009
10.1021/ja00381a009 · External reference
10.1021/ja00168a070
10.1021/ja00168a070 · External reference
FAST-Modelfree: a program for rapid automated analysis of solution NMR spin-relaxation data
10.1023/a:1023808801134 · 2003 · External reference
10.1002/pro.3943
10.1002/pro.3943 · External reference
10.1046/j.0014-2956.2001.02649.x
10.1046/j.0014-2956.2001.02649.x · External reference
IUPred3: prediction of protein disorder enhanced with unambiguous experimental annotation and visualization of evolutionary conservation
10.1093/nar/gkab408 · 2021 · External reference
10.1093/nar/gkz297
10.1093/nar/gkz297 · External reference
Contributions of tryptophan side chains to the far-ultraviolet circular dichroism of proteins
10.1007/bf00213575 · 1994 · External reference
Circular dichroism techniques for the analysis of intrinsically disordered proteins and domains
10.1007/978-1-61779-927-3_22 · 2012 · External reference
10.1093/bioinformatics/btm477
10.1093/bioinformatics/btm477 · External reference
Crystal structure of a complex between Serratia marcescens metallo-protease and an inhibitor from Erwinia chrysanthemi
10.1006/jmbi.1995.0249 · 1995 · External reference
Crystal structure of a complex between Pseudomonas aeruginosa alkaline protease and its cognate inhibitor: inhibition by a zinc-NH2 coordinative bond
10.1074/jbc.m104020200 · 2001 · External reference
Contribution of a single-turn alpha-helix to the conformational stability and activity of the alkaline proteinase inhibitor of Pseudomonas aeruginosa
10.1021/bi048287q · 2005 · External reference
10.1016/j.biochi.2010.06.004
10.1016/j.biochi.2010.06.004 · External reference
Alkaline proteinase inhibitor of Pseudomonas aeruginosa. Interaction of native and N-terminally truncated inhibitor proteins with Pseudomonas metalloproteinases
2000 · External reference
Unresolved reference
External reference
10.1016/s0968-0004(02)02169-2
10.1016/s0968-0004(02)02169-2 · External reference
Intrinsic disorder in the common N-terminus of human adenovirus 5 E1B–55K and its related E1BN proteins indicated by studies on E1B–93R
10.1016/j.virol.2011.07.012 · 2011 · External reference
10.1110/ps.4210102
10.1110/ps.4210102 · External reference
Characterization of a metalloprotease inhibitor protein (SmaPI) of Serratia marcescens
10.1128/aem.61.8.3035-3041.1995 · 1995 · External reference
Outer membrane proteins Omp10, Omp16, and Omp19 of Brucella spp. are lipoproteins
10.1128/iai.67.9.4960-4962.1999 · 1999 · External reference
The lipocalin protein family: structural and sequence overview
2000 · External reference
Lipocalins - a family portrait
10.1016/j.jplph.2005.12.007 · 2006 · External reference
10.1073/pnas.94.22.11845
10.1073/pnas.94.22.11845 · External reference
A comparison of staphostatin B with standard mechanism serine protease inhibitors
10.1074/jbc.m411792200 · 2005 · External reference
The Leu-3 residue of Serratia marcescens metalloprotease inhibitor is important in inhibitory activity and binding with Serratia marcescens metalloprotease
10.1006/abbi.1997.0561 · 1998 · External reference
10.1021/bi961799n
10.1021/bi961799n · External reference
10.1039/c1mb05401e
10.1039/c1mb05401e · External reference
10.1016/j.abb.2019.07.020
10.1016/j.abb.2019.07.020 · External reference
Rapid <em>In Vivo</em> assessment of adjuvant's cytotoxic T lymphocytes generation capabilities for vaccine development
2018 · External reference
10.1021/bi012159
10.1021/bi012159 · External reference
Binding-induced folding transitions in calpastatin subdomains A and C
10.1110/ps.03138803 · 2003 · External reference
10.1371/journal.pone.0062562
10.1371/journal.pone.0062562 · External reference
10.1016/j.dci.2012.10.005
10.1016/j.dci.2012.10.005 · External reference
Structural studies of p21Waf1/Cip1/Sdi1 in the free and Cdk2-bound state: conformational disorder mediates binding diversity
10.1073/pnas.93.21.11504 · 1996 · External reference
Small peptides inhibit gut trypsin-like proteases and impair Anticarsia gemmatalis (Lepidoptera: Noctuidae) survival and development
10.1002/ps.6191 · 2021 · External reference
10.2174/0929867325666181016163630
10.2174/0929867325666181016163630 · External reference
Accurate bond and angle parameters for X-ray protein structure refinement
10.1107/s0108767391001071 · 1991 · External reference
