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References from Fully automated virtual screening pipeline of FDA-approved drugs using Caver Web. Local targets link to admitted publications; unresolved targets remain external evidence.
10.1016/j.chembiol.2015.11.008
10.1016/j.chembiol.2015.11.008 · External reference
10.1016/j.drudis.2013.07.001
10.1016/j.drudis.2013.07.001 · External reference
10.1038/s41586-021-03819-2
10.1038/s41586-021-03819-2 · External reference
10.1038/nrd4336
10.1038/nrd4336 · External reference
10.1038/nature11247
10.1038/nature11247 · External reference
10.1038/nature13302
10.1038/nature13302 · External reference
Comparative Proteomic Analysis of Eleven Common Cell Lines Reveals Ubiquitous but Varying Expression of Most Proteins
10.1074/mcp.m111.014050 · 2012 · External reference
10.1038/nature13319
10.1038/nature13319 · External reference
Tissue-Based Map of the Human Proteome
2015 · External reference
10.1016/j.jhealeco.2016.01.012
10.1016/j.jhealeco.2016.01.012 · External reference
Financial Aspects and the Future of the Pharmaceutical Industry in the United States of America
10.5455/msm.2013.25.286-290 · 2013 · External reference
10.1093/bioinformatics/btz386
10.1093/bioinformatics/btz386 · External reference
10.1093/nar/gkp359
10.1093/nar/gkp359 · External reference
MoMA-LigPath: A Web Server to Simulate Protein-Ligand Unbinding
10.1093/nar/gkt380 · 2013 · External reference
10.1002/jcc.21334
10.1002/jcc.21334 · External reference
10.1080/17460441.2019.1604677
10.1080/17460441.2019.1604677 · External reference
10.1038/nature03197
10.1038/nature03197 · External reference
10.1093/nar/gkz378
10.1093/nar/gkz378 · External reference
3.0: A Tool for the Analysis of Transport Pathways in Dynamic Protein Structures
10.1371/journal.pcbi.1002708 · 2012 · External reference
10.1021/acs.jcim.5b00559
10.1021/acs.jcim.5b00559 · External reference
IDSM ChemWebRDF: SPARQLing Small-Molecule Datasets
10.1186/s13321-021-00515-1 · 2021 · External reference
Fpocket: An Open Source Platform for Ligand Pocket Detection
10.1186/1471-2105-10-168 · 2009 · External reference
10.1093/nar/gkx1012
10.1093/nar/gkx1012 · External reference
10.1093/nar/gky092
10.1093/nar/gky092 · External reference
10.1002/jcc.21256
10.1002/jcc.21256 · External reference
CaverDock: A Novel Method for the Fast Analysis of Ligand Transport
10.1109/tcbb.2019.2907492 · 2020 · External reference
10.1093/nar/gkv951
10.1093/nar/gkv951 · External reference
10.1093/nar/gkr777
10.1093/nar/gkr777 · External reference
A Database and Ontology for Chemical Entities of Biological Interest
10.1093/nar/gkm791 · 2008 · External reference
Unresolved reference
External reference
Phenotype-Genotype Correlation in Eight Chinese 17α-Hydroxylase/17,20 Lyase-Deficiency Patients with Five Novel Mutations of CYP17A1 Gene
10.1210/jc.2005-2283 · 2006 · External reference
Cytochrome P450 Family 17 Subfamily A Member 1 Mutation Causes Severe Pseudohermaphroditism: A Case Report
10.12998/wjcc.v10.i11.3553 · 2022 · External reference
Prevalence of CYP17A1 Gene Mutations in 17α-Hydroxylase Deficiency in the Chinese Han Population
10.1186/s40885-019-0128-6 · 2019 · External reference
Congenital Adrenal Hyperplasia Due to 17-Alpha-Hydoxylase/17,20-Lyase Deficiency Presenting with Hypertension and Pseudohermaphroditism: First Case Report from Oman
10.5001/omj.2014.12 · 2014 · External reference
Two Prevalent CYP17 Mutations and Genotype-Phenotype Correlations in 24 Brazilian Patients with 17-Hydroxylase Deficiency
10.1210/jc.2003-031021 · 2004 · External reference
10.3390/jcm9113555
10.3390/jcm9113555 · External reference
Oxazolinyl Derivatives of [17(20)E]-21-Norpregnene Differing in the Structure of A and B Rings. Facile Synthesis and Inhibition of CYP17A1 Catalytic Activity
10.1016/j.steroids.2016.06.002 · 2016 · External reference
Promising Tools in Prostate Cancer Research: Selective Non-Steroidal Cytochrome P450 17A1 Inhibitors
10.1038/srep29468 · 2016 · External reference
10.1158/1078-0432.ccr-11-0728
10.1158/1078-0432.ccr-11-0728 · External reference
Slow-, Tight-Binding Inhibition of CYP17A1 by Abiraterone Redefines Its Kinetic Selectivity and Dosing Regimen
10.1124/jpet.120.265868 · 2020 · External reference
10.1016/j.mce.2010.11.016
10.1016/j.mce.2010.11.016 · External reference
Structures of Cytochrome P450 17A1 with Prostate Cancer Drugs Abiraterone and TOK-001
10.1038/nature10743 · 2012 · External reference
CYP17 Inhibitors for Prostate Cancer Therapy
10.1016/j.jsbmb.2010.11.005 · 2011 · External reference
Unresolved reference
External reference
Mechanism of the Dual Activities of Human CYP17A1 and Binding to Anti-Prostate Cancer Drug Abiraterone Revealed by a Novel V366M Mutation Causing 17,20 Lyase Deficiency
10.3390/ph11020037 · 2018 · External reference
Ketoconazole Binds to the Human Androgen Receptor
10.1055/s-2007-1003337 · 1992 · External reference
Importance of Asparagine 202 in Manipulating Active Site Structure and Substrate Preference for Human CYP17A1
10.1021/acs.biochem.2c00023 · 2022 · External reference
10.1007/s40257-014-0077-5
10.1007/s40257-014-0077-5 · External reference
Unresolved reference
External reference
Unresolved reference
External reference
Unresolved reference
External reference