Contact and support
Need help, have a question, or want to contact the ResearchHub team?
© 2026 ResearchHub. Built for responsible scholarly connection.
Privacy-aware community infrastructureResearch graph
References from Structure-based discovery and in vitro validation of inhibitors of chloride intracellular channel 4 protein. Local targets link to admitted publications; unresolved targets remain external evidence.
10.1080/19420862.2018.1548232
10.1080/19420862.2018.1548232 · External reference
Three decades of chloride intracellular channel proteins: from organelle to organ physiology
10.1002/cpph.36 · 2018 · External reference
The enigma of the CLIC proteins: ion channels, redox proteins, enzymes, scaffolding proteins?
10.1016/j.febslet.2010.01.027 · 2010 · External reference
The chloride intracellular channel protein CLIC4 inhibits filopodium formation induced by constitutively active mutants of formin mDia2
10.1002/1873-3468.13766 · 2020 · External reference
Emerging biological roles of Cl- intracellular channel proteins
10.1242/jcs.189795 · 2016 · External reference
10.1016/j.devcel.2011.11.008
10.1016/j.devcel.2011.11.008 · External reference
Members of the chloride intracellular ion channel protein family demonstrate glutaredoxin-like enzymatic activity
10.1371/journal.pone.0115699 · 2015 · External reference
TGF-beta signalling is regulated by Schnurri-2-dependent nuclear translocation of CLIC4 and consequent stabilization of phospho-Smad2 and 3
10.1038/ncb1885 · 2009 · External reference
10.1074/jbc.ra118.002779
10.1074/jbc.ra118.002779 · External reference
10.1016/j.bbamem.2013.05.025
10.1016/j.bbamem.2013.05.025 · External reference
CLIC4 regulates cell adhesion and β1 integrin trafficking
2014 · External reference
CLIC4 regulates TGF-β-dependent myofibroblast differentiation to produce a cancer stroma
2013 · External reference
Aberrant chloride intracellular channel 4 expression contributes to endothelial dysfunction in pulmonary arterial hypertension
10.1161/circulationaha.113.006797 · 2014 · External reference
10.1074/jbc.m117.797126
10.1074/jbc.m117.797126 · External reference
10.3389/fphys.2020.00096
10.3389/fphys.2020.00096 · External reference
Chloride channels in cancer: focus on chloride intracellular channel 1 and 4 (CLIC1 AND CLIC4) proteins in tumor development and as novel therapeutic targets
10.1016/j.bbamem.2014.12.012 · 2015 · External reference
CLIC4/Arf6 pathway: a new lead in BMPRII inhibition in pulmonary hypertension
10.1161/circresaha.118.313705 · 2019 · External reference
CLIC4 is a tumor suppressor for cutaneous squamous cell cancer
10.1093/carcin/bgs115 · 2012 · External reference
Chloride intracellular channel 4 involves in the reduced invasiveness of cancer cells treated by photodynamic therapy
10.1002/lsm.22112 · 2013 · External reference
10.1074/jbc.m506724200
10.1074/jbc.m506724200 · External reference
10.1016/j.molmet.2015.01.003
10.1016/j.molmet.2015.01.003 · External reference
10.1016/j.febslet.2010.01.027
10.1016/j.febslet.2010.01.027 · External reference
10.1016/j.lfs.2019.116841
10.1016/j.lfs.2019.116841 · External reference
Identification and characterization of a bacterial homolog of chloride intracellular channel (CLIC) protein
2017 · External reference
10.1016/j.febslet.2010.03.013
10.1016/j.febslet.2010.03.013 · External reference
The bizarre pharmacology of the ATP release channel pannexin1
10.1016/j.neuropharm.2013.02.019 · 2013 · External reference
10.1111/bph.13161
10.1111/bph.13161 · External reference
Pharmacological "cross-inhibition" of connexin hemichannels and swelling activated anion channels
10.1002/glia.20754 · 2009 · External reference
Anion channels of mitochondria
10.1007/164_2016_39 · 2017 · External reference
10.1007/s11064-013-1084-2
10.1007/s11064-013-1084-2 · External reference
10.1111/j.1742-4658.2005.04909.x
10.1111/j.1742-4658.2005.04909.x · External reference
10.1002/jcc.20084
10.1002/jcc.20084 · External reference
Exploring the lapse in druggability: sequence analysis, structural dynamics and binding site characterization of K-RasG12C variant, a feasible oncotherapeutics target
2018 · External reference
10.1074/jbc.m107804200
10.1074/jbc.m107804200 · External reference
10.1515/biolog-2017-0012
10.1515/biolog-2017-0012 · External reference
Possible allosteric binding site on Gyrase B, a key target for novel anti-TB drugs: Homology modelling and binding site identification using molecular dynamics simulation and binding free energy calculations
10.1007/s00044-014-1279-3 · 2015 · External reference
Can we rely on computational predictions to correctly identify ligand binding sites on novel protein drug targets? Assessment of binding site prediction methods and a protocol for validation of predicted binding sites
10.1007/s12013-016-0769-y · 2017 · External reference
Aminoacyl tRNA synthetases as malarial drug targets: a comparative bioinformatics study
10.1186/s12936-019-2665-6 · 2019 · External reference
10.1021/ci800324m
10.1021/ci800324m · External reference
DeepSite: protein-binding site predictor using 3D-convolutional neural networks
10.1093/bioinformatics/btx350 · 2017 · External reference
10.1093/nar/gks441
10.1093/nar/gks441 · External reference
10.1093/bioinformatics/bts310
10.1093/bioinformatics/bts310 · External reference
ProBiS-ligands: a web server for prediction of ligands by examination of protein binding sites
10.1093/nar/gku460 · 2014 · External reference
Unresolved reference
External reference
10.1063/1.448118
10.1063/1.448118 · External reference
OriginPro 9.1: scientific data analysis and graphing software—software review
10.1021/ci500161d · 2014 · External reference
Unresolved reference
2016 · External reference
Druggability analysis and classification of protein tyrosine phosphatase active sites
10.2147/dddt.s111443 · 2016 · External reference
Unresolved reference
2021 · External reference
CLICs-dependent chloride efflux is an essential and proximal upstream event for NLRP3 inflammasome activation
10.1038/s41467-017-00227-x · 2017 · External reference
10.1038/nprot.2007.30
10.1038/nprot.2007.30 · External reference
10.1371/journal.pone.0039378
10.1371/journal.pone.0039378 · External reference
10.1073/pnas.1201351109
10.1073/pnas.1201351109 · External reference
Knockdown of CLIC4 enhances ATP-induced HN4 cell apoptosis through mitochondrial and endoplasmic reticulum pathways
2016 · External reference
Spatiotemporal regulation of chloride intracellular channel protein CLIC4 by RhoA
2019 · External reference
10.1016/j.febslet.2010.01.037
10.1016/j.febslet.2010.01.037 · External reference
Integrated computational approaches and tools for allosteric drug discovery
10.3390/ijms21030847 · 2020 · External reference
10.1021/acs.jmedchem.1c01695
10.1021/acs.jmedchem.1c01695 · External reference
Blenis, rapamycin: one drug, many effects
2019 · External reference
Mammalian target of rapamycin: a metabolic rheostat for regulating adipose tissue function and cardiovascular health
10.1016/j.ajpath.2018.11.013 · 2019 · External reference
