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References from Hybrid computational models of multicellular tumour growth considering glucose metabolism. Local targets link to admitted publications; unresolved targets remain external evidence.
10.1101/gad.1756509
10.1101/gad.1756509 · External reference
10.1146/annurev-cellbio-092910-154237
10.1146/annurev-cellbio-092910-154237 · External reference
10.1016/s0092-8674(00)81683-9
10.1016/s0092-8674(00)81683-9 · External reference
10.1016/j.semcancer.2015.02.006
10.1016/j.semcancer.2015.02.006 · External reference
10.1016/j.cell.2011.02.013
10.1016/j.cell.2011.02.013 · External reference
10.1126/science.123.3191.309
10.1126/science.123.3191.309 · External reference
Metabolic plasticity allows cancer cells to thrive under nutrient starvation
10.1073/pnas.2102057118 · 2021 · External reference
10.1016/j.bbabio.2017.02.001
10.1016/j.bbabio.2017.02.001 · External reference
10.1038/nrclinonc.2016.60
10.1038/nrclinonc.2016.60 · External reference
Lung tumor growth correlates with glucose metabolism measured by fluoride-18 fluorodeoxyglucose positron emission tomography
10.1016/0003-4975(95)00754-9 · 1995 · External reference
10.1016/j.tibs.2015.12.001
10.1016/j.tibs.2015.12.001 · External reference
10.1038/nrm2236
10.1038/nrm2236 · External reference
10.1088/1478-3975/ab1a09
10.1088/1478-3975/ab1a09 · External reference
10.1042/bst20150153
10.1042/bst20150153 · External reference
Unresolved reference
2010 · External reference
Hybrid models of tumor growth
10.1002/wsbm.102 · 2011 · External reference
10.1038/nrc4029
10.1038/nrc4029 · External reference
Continuum versus discrete model: a comparison for multicellular tumour spheroids
10.1098/rsta.2006.1780 · 2006 · External reference
Multiphase modelling of tumour growth and extracellular matrix interaction: mathematical tools and applications
10.1007/s00285-008-0218-7 · 2009 · External reference
A history of the study of solid tumour growth: the contribution of mathematical modelling
10.1016/j.bulm.2003.11.002 · 2004 · External reference
A review of cell-based computational modeling in cancer biology
10.1200/cci.18.00069 · 2019 · External reference
10.1007/s40571-015-0082-3
10.1007/s40571-015-0082-3 · External reference
10.1016/j.jtbi.2007.01.027
10.1016/j.jtbi.2007.01.027 · External reference
BioDynaMo: a modular platform for high-performance agent-based simulation
10.1093/bioinformatics/btab649 · 2022 · External reference
10.1371/journal.pcbi.1002970
10.1371/journal.pcbi.1002970 · External reference
Multi-scale modeling of tissues using CompuCell3D
10.1016/b978-0-12-388403-9.00013-8 · 2012 · External reference
Hybrid automata library: a flexible platform for hybrid modeling with real-time visualization
10.1371/journal.pcbi.1007635 · 2020 · External reference
10.1111/j.1462-2920.2011.02414.x
10.1111/j.1462-2920.2011.02414.x · External reference
Morpheus: a user-friendly modeling environment for multiscale and multicellular systems biology
10.1093/bioinformatics/btt772 · 2014 · External reference
PhysiCell: an open source physics-based cell simulator for 3-D multicellular systems
10.1371/journal.pcbi.1005991 · 2018 · External reference
An in silico hybrid continuum-agent-based procedure to modelling cancer development: interrogating the interplay amongst glioma invasion, vascularity and necrosis
10.1016/j.ymeth.2020.01.006 · 2021 · External reference
10.1038/nrc2808
10.1038/nrc2808 · External reference
Inferring growth control mechanisms in growing multi-cellular spheroids of NSCLC cells from spatial-temporal image data
10.1371/journal.pcbi.1004412 · 2016 · External reference
10.1016/j.isci.2021.102935
10.1016/j.isci.2021.102935 · External reference
Agent-based models in cellular systems
2023 · External reference
Metabolic reprogramming dynamics in tumor spheroids: Insights from a multicellular, multiscale model
10.1371/journal.pcbi.1007053 · 2019 · External reference
10.1126/science.1160809
10.1126/science.1160809 · External reference
Fundamentals of cancer metabolism
10.1126/sciadv.1600200 · 2016 · External reference
10.1126/science.124.3215.269
10.1126/science.124.3215.269 · External reference
Unresolved reference
1955 · External reference
10.1126/science.1058079
10.1126/science.1058079 · External reference
10.1038/nrc.2016.77
10.1038/nrc.2016.77 · External reference
Unresolved reference
2021 · External reference
10.1007/s11033-015-3857-y
10.1007/s11033-015-3857-y · External reference
Crosstalk between the Warburg effect, redox regulation and autophagy induction in tumourigenesis
10.1186/s11658-018-0088-y · 2018 · External reference
Tumor acidity as evolutionary spite
10.3390/cancers3010408 · 2011 · External reference
Systems analysis of intracellular pH vulnerabilities for cancer therapy
10.1038/s41467-018-05261-x · 2018 · External reference
10.4161/cc.8.23.10238
10.4161/cc.8.23.10238 · External reference
10.1038/ncb3278
10.1038/ncb3278 · External reference
10.1038/s12276-020-00504-8
10.1038/s12276-020-00504-8 · External reference
10.1016/j.tibs.2010.05.003
10.1016/j.tibs.2010.05.003 · External reference
10.1007/bf00391431
10.1007/bf00391431 · External reference
Growth of multicell spheroids in tissue culture as a model of nodular carcinomas
1971 · External reference
10.1016/j.jbiotec.2010.01.012
10.1016/j.jbiotec.2010.01.012 · External reference
Challenges of applying multicellular tumor spheroids in preclinical phase
10.1186/s12935-021-01853-8 · 2021 · External reference
Multicellular spheroids: a three‐dimensional in vitro culture system to study tumour biology
10.1046/j.1365-2613.1998.00051.x · 2002 · External reference
Designing and interpreting 4D tumour spheroid experiments
10.1038/s42003-022-03018-3 · 2022 · External reference
Glucose diffusivity in multicellular tumor spheroids
1988 · External reference
Variations in tumor cell growth rates and metabolism with oxygen concentration, glucose concentration, and extracellular pH
10.1002/jcp.1041510220 · 1992 · External reference
Modeling and measuring glucose diffusion and consumption by colorectal cancer spheroids in hanging drops using integrated biosensors
10.1038/s41378-021-00348-w · 2022 · External reference
10.1006/jtbi.2000.2000
10.1006/jtbi.2000.2000 · External reference
Gap junctions amplify spatial variations in cell volume in proliferating tumor spheroids
10.1038/s41467-020-19904-5 · 2020 · External reference
10.1158/0008-5472.can-12-4355
10.1158/0008-5472.can-12-4355 · External reference
The hallmarks of mathematical oncology
10.1109/jproc.2021.3136715 · 2022 · External reference
Differences in predictions of ODE models of tumor growth: a cautionary example
10.1186/s12885-016-2164-x · 2016 · External reference
Classical mathematical models for description and prediction of experimental tumor growth
10.1371/journal.pcbi.1003800 · 2014 · External reference
Dynamics of tumor growth
10.1038/bjc.1964.55 · 1964 · External reference
A Gompertzian model of human breast cancer growth
1988 · External reference
Population modeling of tumor growth curves and the reduced Gompertz model improve prediction of the age of experimental tumors
10.1371/journal.pcbi.1007178 · 2020 · External reference
Classical mathematical models for description and prediction of experimental tumor growth
10.1371/journal.pcbi.1003800 · 2014 · External reference
Models for the growth of a solid tumor by diffusion
10.1002/sapm1972514317 · 1972 · External reference
Rate of growth of solid tumours as a problem of diffusion
1966 · External reference
CBMOS: a GPU-enabled Python framework for the numerical study of center-based models
10.1186/s12859-022-04575-4 · 2022 · External reference
Biomechanical modelling of cancer: agent‐based force‐based models of solid tumours within the context of the tumour microenvironment
2021 · External reference
10.1371/journal.pcbi.1008764
10.1371/journal.pcbi.1008764 · External reference
10.1016/j.semcancer.2014.04.001
10.1016/j.semcancer.2014.04.001 · External reference
A hybrid computational model to explore the topological characteristics of epithelial tissues
10.1002/cnm.2877 · 2017 · External reference
10.1371/journal.pcbi.1007961
10.1371/journal.pcbi.1007961 · External reference
Mathematical modeling of the function of warburg effect in tumor microenvironment
10.1038/s41598-018-27303-6 · 2018 · External reference
10.1016/j.jtbi.2009.01.034
10.1016/j.jtbi.2009.01.034 · External reference
10.1158/0008-5472.can-14-1428
10.1158/0008-5472.can-14-1428 · External reference
10.1016/j.semcancer.2014.04.003
10.1016/j.semcancer.2014.04.003 · External reference
10.3390/pr9020322
10.3390/pr9020322 · External reference
10.1016/s0958-1669(00)00079-3
10.1016/s0958-1669(00)00079-3 · External reference
10.1016/j.bpj.2009.09.064
10.1016/j.bpj.2009.09.064 · External reference
10.1098/rsif.2020.0341
10.1098/rsif.2020.0341 · External reference
10.1016/j.csbj.2021.08.004 · Admitted local publication
10.1038/nrg3643
10.1038/nrg3643 · External reference
Flux balance analysis predicts essential genes in clear cell renal cell carcinoma metabolism
10.1038/srep10738 · 2015 · External reference
Model-based metabolism design: constraints for kinetic and stoichiometric models
10.1042/bst20170263 · 2018 · External reference
Mathematical modeling of intracellular signaling pathways
2016 · External reference
10.1371/journal.pcbi.1009841
10.1371/journal.pcbi.1009841 · External reference
Computational modeling to determine key regulators of hypoxia effects on the lactate production in the glycolysis pathway
10.1038/s41598-020-66059-w · 2020 · External reference
10.1073/pnas.1816391116
10.1073/pnas.1816391116 · External reference
Studying metabolic flux adaptations in cancer through integrated experimental-computational approaches
10.1186/s12915-019-0669-x · 2019 · External reference
Necrotic core in EMT6/Ro tumour spheroids: Is it caused by an ATP deficit?
2010 · External reference
10.1016/j.bpj.2016.07.028
10.1016/j.bpj.2016.07.028 · External reference
10.1529/biophysj.105.060640
10.1529/biophysj.105.060640 · External reference
A quantitative cellular automaton model of in vitro multicellular spheroid tumour growth
10.1016/j.jtbi.2009.02.008 · 2009 · External reference
Multi-scale computational study of the Warburg effect, reverse Warburg effect and glutamine addiction in solid tumors
10.1371/journal.pcbi.1006584 · 2018 · External reference
Agent-based model of multicellular tumor spheroid evolution including cell metabolism
10.1140/epje/i2019-11878-7 · 2019 · External reference
10.1038/nrc2329
10.1038/nrc2329 · External reference
Multi-scale modelling and simulation in systems biology
10.1039/c0ib00075b · 2011 · External reference
10.1146/annurev-bioeng-071811-150104
10.1146/annurev-bioeng-071811-150104 · External reference
Modeling of self-organized avascular tumor growth with a hybrid cellular automaton
2002 · External reference
10.1371/journal.pcbi.1008845
10.1371/journal.pcbi.1008845 · External reference
10.1088/1758-5090/abe025
10.1088/1758-5090/abe025 · External reference
10.1371/journal.pone.0127972
10.1371/journal.pone.0127972 · External reference
A biophysical model of cell evolution after cytotoxic treatments: Damage, repair and cell response
10.1016/j.jtbi.2015.10.017 · 2016 · External reference
10.1002/jcp.1041240323
10.1002/jcp.1041240323 · External reference
10.1016/j.jtbi.2006.03.011
10.1016/j.jtbi.2006.03.011 · External reference
10.1098/rsif.2017.0703
10.1098/rsif.2017.0703 · External reference
10.1371/journal.pone.0240765
10.1371/journal.pone.0240765 · External reference
10.1006/jtbi.2001.2385
10.1006/jtbi.2001.2385 · External reference
Microenvironment driven invasion: a multiscale multimodel investigation
10.1007/s00285-008-0210-2 · 2008 · External reference
Metabolic changes during carcinogenesis: potential impact on invasiveness
10.1016/j.jtbi.2006.09.010 · 2007 · External reference
Three-dimensional tumor growth in time-varying chemical fields: a modeling framework and theoretical study
10.1186/s12859-019-2997-9 · 2019 · External reference
Feedback between mechanosensitive signaling and active forces governs endothelial junction integrity
10.1038/s41467-022-34701-y · 2022 · External reference
10.1371/journal.pcbi.1006395
10.1371/journal.pcbi.1006395 · External reference
Extracellular matrix stiffness: new areas affecting cell metabolism
2021 · External reference
10.15252/embr.201439246
10.15252/embr.201439246 · External reference
Highly motile cells are metabolically responsive to collagen density
10.1073/pnas.2114672119 · 2022 · External reference
Mechanisms linking mechanotransduction and cell metabolism
10.1096/fasebj.2020.34.s1.00150 · 2020 · External reference
The stiffness of living tissues and its implications for their engineering. Nature Reviews
2020 · External reference
10.1038/s41467-020-18794-x
10.1038/s41467-020-18794-x · External reference
10.1016/j.cell.2018.08.017
10.1016/j.cell.2018.08.017 · External reference
10.1038/s41563-021-01057-5
10.1038/s41563-021-01057-5 · External reference
10.1126/science.aaw6985
10.1126/science.aaw6985 · External reference
Seven challenges in the multiscale modeling of multicellular tissues
10.1002/wsbm.1527 · 2022 · External reference
Effect of particularisation size on the accuracy and efficiency of a multiscale tumours’ growth model
10.1002/cnm.3657 · 2022 · External reference