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References from Genome-scale models as a vehicle for knowledge transfer from microbial to mammalian cell systems. Local targets link to admitted publications; unresolved targets remain external evidence.
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Multiplex secretome engineering enhances recombinant protein production and purity
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Synergising stoichiometric modelling with artificial neural networks to predict antibody glycosylation patterns in Chinese hamster ovary cells
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A nutrition algorithm to optimize feed and medium composition using genome-scale metabolic models
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Exploring gene knockout strategies to identify potential drug targets using genome-scale metabolic models
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Erroneous energy-generating cycles in published genome scale metabolic networks: identification and removal
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Genome-scale metabolic network reconstruction of model animals as a platform for translational research
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An unconventional uptake rate objective function approach enhances applicability of genome-scale models for mammalian cells
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Machine and deep learning meet genome-scale metabolic modeling
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The poly-omics of ageing through individual-based metabolic modelling
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Integration of machine learning and genome-scale metabolic modeling identifies multi-omics biomarkers for radiation resistance
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Recent advances in genome-scale modeling of proteome allocation
10.1016/j.coisb.2021.04.002 · 2021 · External reference
Genome-scale models of metabolism and gene expression extend and refine growth phenotype prediction
10.1038/msb.2013.52 · 2013 · External reference
Integration of enzymatic data in Bacillus subtilis genome-scale metabolic model improves phenotype predictions and enables in silico design of poly-γ-glutamic acid production strains
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Recon 2.2: from reconstruction to model of human metabolism
10.1007/s11306-016-1051-4 · 2016 · External reference
A consensus genome-scale reconstruction of Chinese hamster ovary cell metabolism
10.1016/j.cels.2016.10.020 · 2016 · External reference
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10.1038/msb.2009.82 · External reference
Economics of membrane occupancy and respiro-fermentation
10.1038/msb.2011.34 · 2011 · External reference
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2020 · External reference
The metabolic landscape of lung cancer: new insights in a disturbed glucose metabolism
2019 · External reference
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Lactate metabolism shift in CHO cell culture: the role of mitochondrial oxidative activity
10.1016/j.nbt.2012.05.021 · 2013 · External reference
Elevated pCO(2) affects the lactate metabolic shift in CHO cell culture processes
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Designing a strategy for pH control to improve CHO cell productivity in bioreactor
2021 · External reference
Proteome constraints reveal targets for improving microbial fitness in nutrient-rich environments
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10.1038/ncomms1928 · 2012 · External reference
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Enzyme capacity-based genome scale modelling of CHO cells
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10.1371/journal.pcbi.1002575 · External reference
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The ETFL formulation allows multi-omics integration in thermodynamics-compliant metabolism and expression models
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