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References from In silico screening of phenylethanoid glycosides, a class of pharmacologically active compounds as natural inhibitors of SARS-CoV-2 proteases. Local targets link to admitted publications; unresolved targets remain external evidence.
10.1056/nejmoa2001017
10.1056/nejmoa2001017 · External reference
SARS-CoV-2
2021 · External reference
Pathogenesis of multiple organ injury in COVID-19 and potential therapeutic strategies
10.3389/fphys.2021.593223 · 2021 · External reference
COVID-19 therapeutics
2022 · External reference
SARS-CoV-2: phenotype, genotype, and characterization of different variants
10.1186/s11658-022-00352-6 · 2022 · External reference
SARS-CoV-2 ORF8: one protein, seemingly one structure, and many functions
10.3389/fimmu.2022.1035559 · 2022 · External reference
10.3390/cells10040821
10.3390/cells10040821 · External reference
10.1016/j.jmb.2020.11.024
10.1016/j.jmb.2020.11.024 · External reference
10.1126/science.abb3405
10.1126/science.abb3405 · External reference
10.3390/cells10040821
10.3390/cells10040821 · External reference
10.1007/s11427-021-1964-4
10.1007/s11427-021-1964-4 · External reference
10.1128/jvi.78.24.13600-13612.2004
10.1128/jvi.78.24.13600-13612.2004 · External reference
Structure of papain-like protease from SARS-CoV-2 and its complexes with non-covalent inhibitors
10.1038/s41467-021-21060-3 · 2021 · External reference
Flavonoids with inhibitory activity against SARS-CoV-2 3CLpro
10.1080/14756366.2020.1801672 · 2020 · External reference
Impact of the double mutants on spike protein of SARS-CoV-2 B.1.617 lineage to the human ACE2 receptor binding: a structural insight
2021 · External reference
Caffeic acid derivatives (CAFDs) as inhibitors of SARS-CoV-2: CAFDs-based functional foods as a potential alternative approach to combat COVID-19
10.1016/j.phymed.2020.153310 · 2021 · External reference
Repurposing of some natural product isolates as sars-cov-2 main protease inhibitors via in vitro cell free and cell-based antiviral assessments and molecular modeling approaches
10.3390/ph14030213 · 2021 · External reference
Emergence and expansion of highly infectious spike protein D614G mutant SARS-CoV-2 in central India
2021 · External reference
Marine natural compounds as potents inhibitors against the main protease of SARS-CoV-2—a molecular dynamic study
2020 · External reference
Flavonoids with inhibitory activity against SARS-CoV-2 3CLpro
10.1080/14756366.2020.1801672 · 2020 · External reference
Flavonoids from Siparuna cristata as Potential Inhibitors of SARS-CoV-2 Replication
2021 · External reference
A review on the structure and pharmacological activity of phenylethanoid glycosides
10.1016/j.ejmech.2020.112563 · 2021 · External reference
10.1039/d0ra05126h
10.1039/d0ra05126h · External reference
10.1080/07391102.2020.1832580
10.1080/07391102.2020.1832580 · External reference
In silico study of potential anti-SARS cell entry phytoligands from Phlomis aurea: a promising avenue for prophylaxis
10.2217/fvl-2021-0031 · 2021 · External reference
Phenylpropanoid, neolignan and iridoid glycosides from Pedicularis semitorta
1997 · External reference
Natural products for the prevention and control of the COVID-19 pandemic: sustainable bioresources
10.3389/fphar.2021.758159 · 2021 · External reference
10.3390/ph15070794
10.3390/ph15070794 · External reference
Efficacy and safety of Lianhuaqingwen capsules, a repurposed Chinese herb, in patients with coronavirus disease 2019: a multicenter, prospective, randomized controlled trial
2021 · External reference
Lianhuaqingwen exerts anti-viral and anti-inflammatory activity against novel coronavirus (SARS-CoV-2)
10.1016/j.phrs.2020.104761 · 2020 · External reference
Phenylethanoid glycosides in plants: structure and biological activity
10.1039/np9941100591 · 1994 · External reference
Naturally occurring phenylethanoid glycosides: potential leads for new therapeutics
10.2174/092986708785908996 · 2008 · External reference
Phenylethanoid glycosides: research advances in their phytochemistry, pharmacological activity and pharmacokinetics
2016 · External reference
Therapeutic potential of phenylethanoid glycosides: a systematic review
10.1002/med.21717 · 2020 · External reference
PDB2PQR: expanding and upgrading automated preparation of biomolecular structures for molecular simulations
10.1093/nar/gkm276 · 2007 · External reference
10.1002/jcc.20084
10.1002/jcc.20084 · External reference
10.1038/nprot.2016.051
10.1038/nprot.2016.051 · External reference
Open Babel: an open chemical toolbox
10.1186/1758-2946-3-33 · 2011 · External reference
Establishing an analogue based in silico pipeline in the pursuit of novel inhibitory scaffolds against the sars coronavirus 2 papain-like protease
10.3390/molecules26041134 · 2021 · External reference
10.1021/acscentsci.1c00519
10.1021/acscentsci.1c00519 · External reference
10.1038/s41467-020-20718-8
10.1038/s41467-020-20718-8 · External reference
10.1016/j.bmcl.2020.127377
10.1016/j.bmcl.2020.127377 · External reference
Targeting SARS-CoV-2: a systematic drug repurposing approach to identify promising inhibitors against 3C-like proteinase and 2′-O-ribose methyltransferase
2020 · External reference
The SARS-coronavirus papain-like protease: structure, function and inhibition by designed antiviral compounds
10.1016/j.antiviral.2014.12.015 · 2015 · External reference
10.1038/s41467-021-21060-3
10.1038/s41467-021-21060-3 · External reference
10.1038/s41467-020-20718-8
10.1038/s41467-020-20718-8 · External reference
Antioxidative phenylethanoid and phenolic glycosides from Picrorhiza scrophulariiflora
10.1248/cpb.52.615 · 2004 · External reference
10.1002/hlca.200490057
10.1002/hlca.200490057 · External reference
10.1016/j.drudis.2011.02.016
10.1016/j.drudis.2011.02.016 · External reference
10.3390/molecules27144568
10.3390/molecules27144568 · External reference
10.1007/s12272-015-0640-5
10.1007/s12272-015-0640-5 · External reference
When virtual screening yields to inactive drugs dealing with false theoretical‐friends
2022 · External reference
The pharmacogenetics of natural products: a pharmacokinetic and pharmacodynamic perspective
2019 · External reference
Unresolved reference
External reference
10.1021/acs.jpclett.1c01460
10.1021/acs.jpclett.1c01460 · External reference
Structure-function characteristics of sars-cov-2 proteases and their potential inhibitors from microbial sources
2021 · External reference
The complex structure of GRL0617 and SARS-CoV-2 PLpro reveals a hot spot for antiviral drug discovery
2021 · External reference
Analysis on herbal medicines utilized for treatment of COVID-19
10.1016/j.apsb.2020.05.007 · 2020 · External reference
Chinese herbal medicine for coronavirus disease 2019: a systematic review and meta-analysis
10.1016/j.phrs.2020.105056 · 2020 · External reference
Recent clinical trials on natural products and traditional Chinese medicine combating the COVID-19
10.1007/s12088-020-00919-x · 2021 · External reference
Potential treatment of COVID-19 with traditional chinese medicine: what herbs can help win the battle with SARS-CoV-2
2021 · External reference
Analysis of Chinese herbal formulae recommended for COVID-19 in different schemes in China: a data mining approach
10.2174/1386207323666201001114101 · 2021 · External reference
Unresolved reference
External reference
10.1038/s41579-020-00459-7
10.1038/s41579-020-00459-7 · External reference
Chemical structures of constituents from the whole plant of Bacopa monniera
10.1007/s11418-016-0986-0 · 2016 · External reference
A new phenylethanoid glucoside from Jacaranda mimosifolia
10.1080/14786419.2012.717290 · 2013 · External reference
Four new phenylethanoid glycosides from Ternstroemia gymnanthera and their analgesic activities
10.1016/j.phytol.2019.09.009 · 2019 · External reference
Pedicularis L. Genus: systematics, botany, phytochemistry, chemotaxonomy, ethnopharmacology, and other
2019 · External reference
New phenethyl alcohol glycosides from Stachys parviflora
10.1080/10286020500478708 · 2006 · External reference
Eight new phenylethanoid glycoside derivatives possessing potential hepatoprotective activities from the fruits of Forsythia suspensa
10.1016/j.fitote.2017.09.008 · 2017 · External reference
The pharmacogenetics of natural products: a pharmacokinetic and pharmacodynamic perspective
10.1016/j.phrs.2019.104283 · 2019 · External reference
Lead- and drug-like compounds: the rule-of-five revolution
10.1016/j.ddtec.2004.11.007 · 2004 · External reference
10.1016/j.chembiol.2014.08.013
10.1016/j.chembiol.2014.08.013 · External reference
How beyond rule of 5 drugs and clinical candidates bind to their targets
2015 · External reference
10.1080/17460441.2017.1264385
10.1080/17460441.2017.1264385 · External reference
pkCSM: predicting small-molecule pharmacokinetic and toxicity properties using graph-based signatures
10.1021/acs.jmedchem.5b00104 · 2015 · External reference
10.1038/srep42717
10.1038/srep42717 · External reference
10.1021/ci500588j
10.1021/ci500588j · External reference
10.1021/ci050358k
10.1021/ci050358k · External reference
An improved bacterial test system for the detection and classification of mutagens and carcinogens
10.1073/pnas.70.3.782 · 1973 · External reference
10.1038/srep42717
10.1038/srep42717 · External reference
10.1016/j.ejpb.2019.07.013
10.1016/j.ejpb.2019.07.013 · External reference
10.1126/science.abb3405
10.1126/science.abb3405 · External reference
10.1126/science.abb4489
10.1126/science.abb4489 · External reference
10.1016/j.jiph.2020.06.016
10.1016/j.jiph.2020.06.016 · External reference
Reynoutria rhizomes as a natural source of sars-cov-2 mpro inhibitors–molecular docking and in vitro study
10.3390/ph14080742 · 2021 · External reference
Large-scale computational drug repositioning to find treatments for rare diseases
10.1038/s41540-018-0050-7 · 2018 · External reference
Unresolved reference
External reference
Supporting SARS-CoV-2 papain-like protease drug discovery: in silico methods and benchmarking
10.3389/fchem.2020.592289 · 2020 · External reference
Unresolved reference
External reference
Identifying structural–functional analogue of GRL0617, the only well-established inhibitor for papain-like protease (PLpro) of SARS-CoV2 from the pool of fungal metabolites using docking and molecular dynamics simulation
10.1007/s11030-021-10220-8 · 2022 · External reference