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References from Computational tools for exploring peptide-membrane interactions in gram-positive bacteria. Local targets link to admitted publications; unresolved targets remain external evidence.
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2019 · External reference
Screening strategies for quorum sensing inhibitors in combating bacterial infections
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iQSP: A Sequence-Based Tool for the Prediction and Analysis of Quorum Sensing Peptides via Chou's 5-Steps Rule and Informative Physicochemical Properties
2019 · External reference
Staquorsin: A Novel Staphylococcus aureus Agr-Mediated Quorum Sensing Inhibitor Impairing Virulence in vivo Without Notable Resistance Development
10.3389/fmicb.2021.700494 · 2021 · External reference
Baicalein Inhibits Staphylococcus aureus Biofilm Formation and the Quorum Sensing System In Vitro
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Structure, activity and evolution of the group I thiolactone peptide quorum-sensing system of Staphylococcus aureus
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PapRIV, a BV-2 microglial cell activating quorum sensing peptide
10.1038/s41598-021-90030-y · 2021 · External reference
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Peptides as quorum sensing molecules: measurement techniques and obtained levels in vitro and in vivo
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Quorum sensing in Staphylococcus infections
10.1172/jci200320442 · 2003 · External reference
Staphylococcus aureus pathogenesis in diverse host environments
2017 · External reference
Anti-quorum sensing activities of gliptins against pseudomonas aeruginosa and staphylococcus aureus
2022 · External reference
10.1074/jbc.m205367200
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Timing is everything: impact of naturally occurring staphylococcus aureus AgrC cytoplasmic domain adaptive mutations on autoinduction
2019 · External reference
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Quorum sensing and biofilm formation in Streptococcal infections
10.1172/jci200320430 · 2003 · External reference
Quorum sensing integrates environmental cues, cell density and cell history to control bacterial competence
10.1038/s41467-017-00903-y · 2017 · External reference
The SaeRS two-component system of staphylococcus aureus
2016 · External reference
10.1128/jb.01927-07
10.1128/jb.01927-07 · External reference
The staphylococcal saeRS system coordinates environmental signals with agr quorum sensing
10.1099/mic.0.26575-0 · 2003 · External reference
The auxiliary protein complex SaePQ activates the phosphatase activity of sensor kinase SaeS in the SaeRS two-component system of Staphylococcus aureus
10.1111/j.1365-2958.2012.08198.x · 2012 · External reference
Molecular architecture of the regulatory Locus sae of Staphylococcus aureus and its impact on expression of virulence factors
10.1128/jb.185.21.6278-6286.2003 · 2003 · External reference
The RNPP family of quorum-sensing proteins in Gram-positive bacteria
10.1007/s00253-010-2651-y · 2010 · External reference
10.1371/journal.pone.0002793
10.1371/journal.pone.0002793 · External reference
The peptide pheromone-inducible conjugation system of Enterococcus faecalis plasmid pCF10: cell-cell signalling, gene transfer, complexity and evolution
10.1098/rstb.2007.2043 · 2007 · External reference
The extracellular Phr peptide-Rap phosphatase signaling circuit of Bacillus subtilis
10.2741/913 · 2003 · External reference
10.3390/toxins6082239
10.3390/toxins6082239 · External reference
Conformational change-induced repeat domain expansion regulates Rap phosphatase quorum-sensing signal receptors
10.1371/journal.pbio.1001512 · 2013 · External reference
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10.1016/s0196-9781(01)00488-0
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10.1093/nar/gks1137
10.1093/nar/gks1137 · External reference
10.1016/j.mehy.2012.03.018
10.1016/j.mehy.2012.03.018 · External reference
Machine learning aided construction of the quorum sensing communication network for human gut microbiota
10.1038/s41467-022-30741-6 · 2022 · External reference
Feature selection based on mutual information: criteria of max-dependency, max-relevance, and min-redundancy
10.1109/tpami.2005.159 · 2005 · External reference
10.1142/s0219720005001004
10.1142/s0219720005001004 · External reference
Comparative analysis and prediction of quorum-sensing peptides using feature representation learning and machine learning algorithms
2018 · External reference
10.1016/j.biotechadv.2021.107739
10.1016/j.biotechadv.2021.107739 · External reference
Predicting quorum sensing peptides using stacked generalization ensemble with gradient boosting based feature selection
10.1007/s12275-022-2044-9 · 2022 · External reference
iFeature: a Python package and web server for features extraction and selection from protein and peptide sequences
10.1093/bioinformatics/bty140 · 2018 · External reference
PEPred-Suite: improved and robust prediction of therapeutic peptides using adaptive feature representation learning
10.1093/bioinformatics/btz246 · 2019 · External reference
QSIdb: quorum sensing interference molecules
2021 · External reference
Prediction of biofilm inhibiting peptides: an in silico approach
10.3389/fmicb.2016.00949 · 2016 · External reference
BaAMPs: the database of biofilm-active antimicrobial peptides
10.1080/08927014.2015.1021340 · 2015 · External reference
dPABBs: a novel in silico approach for predicting and designing anti-biofilm peptides
10.1038/srep21839 · 2016 · External reference
10.1021/acsomega.9b04119
10.1021/acsomega.9b04119 · External reference
Identification of new potential inhibitors of quorum sensing through a specialized multi-level computational approach
2021 · External reference
Computational identification of the proteins associated with quorum sensing and biofilm formation in mycobacterium tuberculosis
10.3389/fmicb.2019.03011 · 2019 · External reference
Computational exploration of putative luxr solos in archaea and their functional implications in quorum sensing
10.3389/fmicb.2017.00798 · 2017 · External reference
In silico pharmacology for drug discovery: methods for virtual ligand screening and profiling
10.1038/sj.bjp.0707305 · 2007 · External reference
Identification of a hydrophobic cleft in the LytTR domain of AgrA as a locus for small molecule interactions that inhibit DNA binding
10.1021/bi3011785 · 2012 · External reference
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Labdane diterpenoids from salvia tingitana etl. synergize with clindamycin against methicillin-resistant staphylococcus aureus
2021 · External reference
Repurposing approved drugs as fluoroquinolone potentiators to overcome efflux pump resistance in staphylococcus aureus
10.1128/spectrum.00951-21 · 2021 · External reference
10.1021/acsomega.0c04252
10.1021/acsomega.0c04252 · External reference
Exploring Morin as an anti-quorum sensing agent (anti-QSA) against resistant strains of Staphylococcus aureus
10.1016/j.micpath.2018.12.007 · 2019 · External reference
Identification of a Molecular Latch that Regulates Staphylococcal Virulence
2019 · External reference
10.1016/s0968-0004(99)01503-0
10.1016/s0968-0004(99)01503-0 · External reference
In silico identification of novel compounds as quorum-sensing inhibitors in selected waterborne pathogens
2021 · External reference
Staphylococcus aureus quorum regulator SarA targeted compound, 2-[(methylamino)methyl]phenol inhibits biofilm and down-regulates virulence genes
10.3389/fmicb.2017.01290 · 2017 · External reference
Biofilm-Associated Agr and Sar quorum sensing systems of staphylococcus aureus are inhibited by 3-hydroxybenzoic acid derived from illicium verum
10.1021/acsomega.1c07178 · 2022 · External reference
Strategies and approaches for discovery of small molecule disruptors of biofilm physiology
2021 · External reference
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10.1126/sciadv.aay9597
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Quorum-sensing regulation of antimicrobial resistance in bacteria
2020 · External reference
Boeravinone B, a novel dual inhibitor of NorA Bacterial Efflux pump of staphylococcus aureus and human p-glycoprotein, reduces the biofilm formation and intracellular invasion of bacteria
10.3389/fmicb.2017.01868 · 2017 · External reference
The 1,8-naphthyridines sulfonamides are NorA efflux pump inhibitors
10.1016/j.jgar.2020.11.027 · 2021 · External reference
Capsaicin, a novel inhibitor of the NorA efflux pump, reduces the intracellular invasion of Staphylococcus aureus
10.1093/jac/dks232 · 2012 · External reference
Boronic species as promising inhibitors of the Staphylococcus aureus NorA efflux pump: study of 6-substituted pyridine-3-boronic acid derivatives
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