Research graph
References from Genomic and proteomic biomarker landscape in clinical trials. Local targets link to admitted publications; unresolved targets remain external evidence.
Biomarkers: opportunities and challenges for drug development in the current regulatory landscape
2020 · External reference
10.1038/nbt1235
10.1038/nbt1235 · External reference
Supervised risk predictor of breast cancer based on intrinsic subtypes
10.1200/jco.2008.18.1370 · 2009 · External reference
10.1038/s41588-020-00757-z
10.1038/s41588-020-00757-z · External reference
RNA sequencing in comparison to immunohistochemistry for measuring cancer biomarkers in breast cancer and lung cancer specimens
10.3390/biomedicines8050114 · 2020 · External reference
Serum messenger RNA as a biomarker and its clinical usefulness in malignancies
2008 · External reference
10.1038/nbt.3605
10.1038/nbt.3605 · External reference
Why have protein biomarkers not reached the clinic?
10.1186/gm282 · 2011 · External reference
10.1093/nar/gkaa1067
10.1093/nar/gkaa1067 · External reference
10.1016/j.csbj.2021.05.015 · Admitted local publication
The Clinical Trials Transformation Initiative: innovation through collaboration
10.1038/nrd4442 · 2014 · External reference
10.1093/nar/gkh061
10.1093/nar/gkh061 · External reference
Extraction of relations between genes and diseases from text and large-scale data analysis: Implications for translational research
2015 · External reference
Unresolved reference
External reference
The DisGeNET knowledge platform for disease genomics: 2019 update
2020 · External reference
10.1007/978-3-319-24277-4
10.1007/978-3-319-24277-4 · External reference
10.1093/bioinformatics/btx364
10.1093/bioinformatics/btx364 · External reference
10.1093/bioinformatics/btx657
10.1093/bioinformatics/btx657 · External reference
Drug target ontology to classify and integrate drug discovery data
2017 · External reference
Variation across 141,456 human exomes and genomes reveals the spectrum of loss-of-function intolerance across human protein-coding genes
2019 · External reference
Genetic polymorphisms of cytochrome P450 2D6 (CYP2D6): clinical consequences, evolutionary aspects and functional diversity
2005 · External reference
10.1056/nejmoa2103583
10.1056/nejmoa2103583 · External reference
Neocortical RELN promoter methylation increases significantly after puberty
10.1097/wnr.0b013e328334b343 · 2010 · External reference
Integrative analysis of shared genetic pathogenesis by autism spectrum disorder and obsessive-compulsive disorder
2019 · External reference