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References from Discovery of a highly efficient TylF methyltransferase via random mutagenesis for improving tylosin production. Local targets link to admitted publications; unresolved targets remain external evidence.
Tylosin, a new antibiotic. II. Isolation, properties, and preparation of desmycosin, a microbiologically active degradation product
1961 · External reference
Macrolide antibiotics: binding site, mechanism of action, resistance
10.2174/1568026033452159 · 2003 · External reference
16-membered macrolide antibiotics: a review
10.1016/j.ijantimicag.2017.05.020 · 2018 · External reference
Synthesis and antimicrobial evaluation of 20-deoxo-20-(3,5-dimethylpiperidin-1-yl)desmycosin (tilmicosin, EL-870) and related cyclic amino derivatives
10.7164/antibiotics.42.1253 · 1989 · External reference
Physico-chemical properties of new acyl derivatives of tylosin produced by microbial transformation
10.7164/antibiotics.33.1300 · 1980 · External reference
Visualizing the 16-membered ring macrolides tildipirosin and tilmicosin bound to their ribosomal site
10.1021/cb300105p · 2012 · External reference
Tulathromycin: an overview of a new triamilide antibiotic for livestock respiratory disease
2005 · External reference
Design, synthesis and activity against drug-resistant bacteria evaluation of C-20, C-23 modified 5-O-mycaminosyltylonolide derivatives
10.1016/j.ejmech.2022.114495 · 2022 · External reference
Metabolic products of microorganisms. 113. Biosynthesis of thymidine diphospho mycarose in a cell-free system from Streptomyces rimosus
1973 · External reference
Relomycin: Flask and Tank Fermentation Studies
1963 · External reference
The tylosin-biosynthetic genes of Streptomyces fradiae
10.1023/a:1012065300116 · 2001 · External reference
Genetics of Streptomyces fradiae and tylosin biosynthesis
10.1146/annurev.mi.42.100188.002555 · 1988 · External reference
Properties of Streptomyces fradiae mutants blocked in biosynthesis of the macrolide antibiotic tylosin
10.1128/aac.20.2.214 · 1981 · External reference
Biosynthesis of the macrolide antibiotic tylosin. A preferred pathway from tylactone to tylosin
10.7164/antibiotics.36.131 · 1983 · External reference
Terminal stages in the biosynthesis of tylosin
10.1128/aac.11.3.455 · 1977 · External reference
Properties of S-adenosyl-L-methionine:macrocin O-methyltransferase in extracts of Streptomyces fradiae strains which produce normal or elevated levels of tylosin and in mutants blocked in specific O-methylations
10.1128/aac.20.3.370 · 1981 · External reference
S-Adenosyl-L-methionine: macrocin O-methyltransferase activities in a series of Streptomyces fradiae mutants that produce different levels of the macrolide antibiotic tylosin
10.1128/aac.21.5.758 · 1982 · External reference
Purification, characterization, and kinetic mechanism of S-adenosyl-L-methionine:macrocin O-methyltransferase from Streptomyces fradiae
10.1016/s0021-9258(19)37633-1 · 1988 · External reference
High-throughput screening technologies for enzyme engineering
10.1016/j.copbio.2017.05.012 · 2017 · External reference
10.1146/annurev-biochem-062917-012034
10.1146/annurev-biochem-062917-012034 · External reference
10.1016/j.tibtech.2021.01.002
10.1016/j.tibtech.2021.01.002 · External reference
Randomization of genes by PCR mutagenesis
10.1101/gr.2.1.28 · 1992 · External reference
10.1038/370389a0
10.1038/370389a0 · External reference
Cloning of random-sequence oligodeoxynucleotides
10.1016/0378-1119(86)90180-0 · 1986 · External reference
10.1016/0378-1119(92)90627-2
10.1016/0378-1119(92)90627-2 · External reference
10.1128/mbio.00277-11
10.1128/mbio.00277-11 · External reference
Consistency evaluation between matrix components ratio and microbiological potency of tylosin major components
10.1007/s40199-018-0220-6 · 2018 · External reference
High-throughput system for screening of Cephalosporin C high-yield strain by 48-deep-well microtiter plates
10.1007/s12010-013-0095-4 · 2013 · External reference
Functional analysis of MycE and MycF, two O-methyltransferases involved in the biosynthesis of mycinamicin macrolide antibiotics
10.1002/cbic.200900088 · 2009 · External reference
Characterization of the Two Methylation Steps Involved in the Biosynthesis of Mycinose in Tylosin
10.1021/acs.jnatprod.6b00267 · 2016 · External reference
10.1038/nprot.2010.5
10.1038/nprot.2010.5 · External reference
10.1038/nmeth.3213
10.1038/nmeth.3213 · External reference
Change in colony morphology and kinetics of tylosin production after UV and gamma irradiation mutagenesis of Streptomyces fradiae NRRL-2702
10.1016/j.micres.2007.02.005 · 2009 · External reference
10.1016/j.biotechadv.2015.02.014
10.1016/j.biotechadv.2015.02.014 · External reference
10.1007/s00253-008-1789-3
10.1007/s00253-008-1789-3 · External reference
Random-priming in vitro recombination: an effective tool for directed evolution
10.1093/nar/26.2.681 · 1998 · External reference
10.1016/s0959-440x(02)00391-3
10.1016/s0959-440x(02)00391-3 · External reference
The crystal structure of the novobiocin biosynthetic enzyme NovP: the first representative structure for the TylF O-methyltransferase superfamily
10.1016/j.jmb.2009.10.045 · 2010 · External reference
Structural basis of substrate specificity and regiochemistry in the MycF/TylF family of sugar O-methyltransferases
10.1021/cb5009348 · 2015 · External reference
