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References from Development and validation of a prognostic 15-gene signature for stratifying HER2+/ER+ breast cancer. Local targets link to admitted publications; unresolved targets remain external evidence.
Unresolved reference
External reference
Cancer hallmarks biomarkers and breast cancer molecular subtypes
10.7150/jca.13141 · 2016 · External reference
Intratumor heterogeneity defines treatment-resistant HER2+ breast tumors
10.1002/1878-0261.12375 · 2018 · External reference
What Is the real impact of estrogen receptor status on the prognosis and treatment of HER2-positive early breast cancer?
10.1158/1078-0432.ccr-19-2612 · 2020 · External reference
HER2-positive breast cancer is lost in translation: time for patient-centered research
10.1038/nrclinonc.2017.96 · 2017 · External reference
10.1158/1078-0432.ccr-18-2782
10.1158/1078-0432.ccr-18-2782 · External reference
10.1016/s0140-6736(16)32616-2
10.1016/s0140-6736(16)32616-2 · External reference
Her2 cross talk and therapeutic resistance in breast cancer
10.2741/2978 · 2008 · External reference
Efficacy and safety of neoadjuvant pertuzumab and trastuzumab in women with locally advanced inflammatory or early HER2-positive breast cancer (NeoSphere): a randomised multicentre open-label phase 2 trial
10.1016/s1470-2045(11)70336-9 · 2012 · External reference
Lapatinib with trastuzumab for HER2-positive early breast cancer (NeoALTTO): a randomised open-label multicentre phase 3 trial
10.1016/s0140-6736(11)61847-3 · 2012 · External reference
Molecular heterogeneity and response to neoadjuvant human epidermal growth factor receptor 2 targeting in CALGB 40601, a randomized phase III trial of paclitaxel plus trastuzumab with or without lapatinib
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Prognostic cancer gene expression signatures: current status and challenges
10.3390/cells10030648 · 2021 · External reference
Supervised risk predictor of breast cancer based on intrinsic subtypes
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Supervised risk predictor of breast cancer based on intrinsic subtypes
10.1200/jco.2008.18.1370 · 2009 · External reference
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A new molecular predictor of distant recurrence in ER-Positive HER2-negative breast cancer adds independent information to conventional clinical risk factors
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A fuzzy gene expression-based computational approach improves breast cancer prognostication
10.1186/gb-2010-11-2-r18 · 2010 · External reference
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An integrated TCGA pan-cancer clinical data resource to drive high-quality survival outcome analytics
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TCGAbiolinks: an R/Bioconductor package for integrative analysis of TCGA data
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Unresolved reference
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Unresolved reference
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A scaling normalization method for differential expression analysis of RNA-seq data
2010 · External reference
Bayesian tensor factorization-drive breast cancer subtyping by integrating multi-omics data
10.1016/j.jbi.2021.103958 · 2022 · External reference
CancerSubtypes: an R/Bioconductor package for molecular cancer subtype identification validation and visualization
10.1093/bioinformatics/btx378 · 2017 · External reference
Consensus clustering a resampling-based method for class discovery and Vi - monti - mach learn
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10.1080/01621459.1958.10501452 · External reference
Limma powers differential expression analyses for RNA-sequencing and microarray studies
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10.1073/pnas.0506580102 · External reference
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A unified approach to interpreting model predictions
2017 · External reference
Integrative analysis of complex cancer genomics and clinical profiles using the cBioPortal
2013 · External reference
Comprehensive analyses of tumor immunity: implications for cancer immunotherapy
2016 · External reference
10.1016/j.cell.2017.06.010
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Predicting and characterizing a cancer dependency map of tumors with deep learning
2021 · External reference
10.1016/j.ccr.2009.12.042
10.1016/j.ccr.2009.12.042 · External reference
UBR5 targets tumor suppressor CDC73 proteolytically to promote aggressive breast cancer
2022 · External reference
Targeting ubiquitin protein ligase E3 component N-recognin 5 in cancer cells induces a CD8+ T cell mediated immune response
2020 · External reference
High WDR34 mRNA expression as a potential prognostic biomarker in patients with breast cancer as determined by integrated bioinformatics analysis
2019 · External reference
DCAF4L2 promotes colorectal cancer invasion and metastasis via mediating degradation of NFκb negative regulator PPM1B
2016 · External reference
Retraction: arginine methylation of SHANK2 by PRMT7 promotes human breast cancer metastasis through activating endosomal FAK signalling
2021 · External reference
10.1016/j.tcb.2016.02.001
10.1016/j.tcb.2016.02.001 · External reference
Tumor-infiltrating cd8 t cells predict clinical breast cancer outcomes in young women
2020 · External reference
Molecular characterization of breast and lung tumors by integration of multiple data types with functional sparse-factor analysis
10.1371/journal.pcbi.1006520 · 2018 · External reference