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References from Systems bioengineering approaches for developmental toxicology. Local targets link to admitted publications; unresolved targets remain external evidence.
Some new directions in control theory inspired by systems biology
10.1049/sb:20045006 · 2004 · External reference
Toxicology: a discipline in need of academic anchoring--the point of view of the German Society of Toxicology
10.1007/s00204-015-1577-7 · 2015 · External reference
The era of 3Rs implementation in developmental and reproductive toxicity (DART) testing: current overview and future perspectives
10.1016/j.reprotox.2017.05.006 · 2017 · External reference
Systems toxicology: from basic research to risk assessment
10.1021/tx400410s · 2014 · External reference
An engineering design approach to systems biology
10.1039/c7ib00014f · 2017 · External reference
Bioengineering and systems biology
10.1007/s10439-005-9047-7 · 2006 · External reference
Multiscale computational models of complex biological systems
10.1146/annurev-bioeng-071811-150104 · 2013 · External reference
Synthetic developmental biology: Engineering approaches to guide multicellular organization
10.1016/j.stemcr.2022.02.004 · 2022 · External reference
Modeling and simulation for toxicity assessment
10.3934/mbe.2017034 · 2017 · External reference
The way forward in reproductive/developmental toxicity testing
10.1177/026119290903700609 · 2009 · External reference
Regulatory acceptance of alternative methods in the development and approval of pharmaceuticals
10.1007/978-3-319-33826-2_3 · 2016 · External reference
Systems toxicology
10.14573/altex.2012.2.119 · 2012 · External reference
Developments in toxicogenomics: understanding and predicting compound-induced toxicity from gene expression data
10.1039/c8mo00042e · 2018 · External reference
Bottom-up biology: harnessing engineering to understand nature
10.1016/j.devcel.2016.09.009 · 2016 · External reference
3S - systematic, systemic, and systems biology and toxicology
10.14573/altex.1804051 · 2018 · External reference
Three-dimensional cell culture systems as an in vitro platform for cancer and stem cell modeling
10.4252/wjsc.v11.i12.1065 · 2019 · External reference
Stem-cell-derived trophoblast organoids model human placental development and susceptibility to emerging pathogens
10.1016/j.stem.2022.04.004 · 2022 · External reference
An in vitro model of early anteroposterior organization during human development
10.1038/s41586-020-2383-9 · 2020 · External reference
Individual brain organoids reproducibly form cell diversity of the human cerebral cortex
10.1038/s41586-019-1289-x · 2019 · External reference
Modeling human multi-lineage heart field development with pluripotent stem cells
10.1016/j.stem.2022.08.007 · 2022 · External reference
Generation of hepatic stellate cells from human pluripotent stem cells enables in vitro modeling of liver fibrosis
10.1016/j.stem.2018.05.027 · 2018 · External reference
Unresolved reference
External reference
High-resolution transcriptional and morphogenetic profiling of cells from micropatterned human ESC gastruloid cultures
10.7554/elife.59445 · 2020 · External reference
A combined human gastruloid model of cardiogenesis and neurogenesis
10.1016/j.isci.2022.104486 · 2022 · External reference
Advancing organoid design through co-emergence, assembly, and bioengineering
2023 · External reference
Human pluripotent-stem-cell-derived organoids for drug discovery and evaluation
10.1016/j.stem.2023.04.011 · 2023 · External reference
Generation and long-term culture of advanced cerebral organoids for studying later stages of neural development
10.1038/s41596-020-00433-w · 2021 · External reference
Generation of cerebral organoids from human pluripotent stem cells
10.1038/nprot.2014.158 · 2014 · External reference
Human multilineage pro-epicardium/foregut organoids support the development of an epicardium/myocardium organoid
10.1038/s41467-022-34730-7 · 2022 · External reference
Co-emergence of cardiac and gut tissues promotes cardiomyocyte maturation within human iPSC-derived organoids
10.1016/j.stem.2021.11.007 · 2021 · External reference
Recapitulating human cardio-pulmonary co-development using simultaneous multilineage differentiation of pluripotent stem cells
10.7554/elife.67872 · 2022 · External reference
Self-organizing 3D human trunk neuromuscular organoids
10.1016/j.stem.2019.12.007 · 2020 · External reference
Drug screening in human PSC-cardiac organoids identifies pro-proliferative compounds acting via the mevalonate pathway
10.1016/j.stem.2019.03.009 · 2019 · External reference
High-throughput screening enhances kidney organoid differentiation from human pluripotent stem cells and enables automated multidimensional phenotyping
10.1016/j.stem.2018.04.022 · 2018 · External reference
A scalable organoid model of human autosomal dominant polycystic kidney disease for disease mechanism and drug discovery
10.1016/j.stem.2022.06.005 · 2022 · External reference
A comprehensive human gastric cancer organoid biobank captures tumor subtype heterogeneity and enables therapeutic screening
10.1016/j.stem.2018.09.016 · 2018 · External reference
Chemotherapy-induced neuropathy and drug discovery platform using human sensory neurons converted directly from adult peripheral blood
10.1002/sctm.19-0054 · 2019 · External reference
Human iPSC-derived blood-brain barrier chips enable disease modeling and personalized medicine applications
10.1016/j.stem.2019.05.011 · 2019 · External reference
A scale out approach towards neural induction of human induced pluripotent stem cells for neurodevelopmental toxicity studies
10.1016/j.toxlet.2018.05.018 · 2018 · External reference
A guide to the organ-on-a-chip
2022 · External reference
Modeling the human body on microfluidic chips
10.1016/j.tibtech.2021.01.004 · 2021 · External reference
Organs-on-a-chip: a fast track for engineered human tissues in drug development
10.1016/j.stem.2018.02.011 · 2018 · External reference
A microfluidic culture model of the human reproductive tract and 28-day menstrual cycle
10.1038/ncomms14584 · 2017 · External reference
Quantitative prediction of human pharmacokinetic responses to drugs via fluidically coupled vascularized organ chips
10.1038/s41551-019-0498-9 · 2020 · External reference
Review of the state of science and evaluation of currently available in silico prediction models for reproductive and developmental toxicity: a case study on pesticides
10.1002/bdr2.2062 · 2022 · External reference
Integrated analysis of multi-omics data on epigenetic changes caused by combined exposure to environmental hazards
10.1002/tox.23099 · 2021 · External reference
A stepwise model of reaction-diffusion and positional information governs self-organized human peri-gastrulation-like patterning
2017 · External reference
Mechanics-guided embryonic patterning of neuroectoderm tissue from human pluripotent stem cells
10.1038/s41563-018-0082-9 · 2018 · External reference
Engineering the spatiotemporal mosaic self-patterning of pluripotent stem cells
10.1007/978-1-0716-1174-6_8 · 2021 · External reference
Automated design of pluripotent stem cell self-organization
10.1016/j.cels.2019.10.008 · 2019 · External reference
Mathematical models of organoid cultures
10.3389/fgene.2019.00873 · 2019 · External reference
A systematically reduced mathematical model for organoid expansion
10.3389/fbioe.2021.670186 · 2021 · External reference
Towards personalized computational oncology: from spatial models of tumour spheroids, to organoids, to tissues
10.1098/rsif.2017.0703 · 2018 · External reference
Engineering cell fitness: lessons for regenerative medicine
10.1016/j.copbio.2017.05.005 · 2017 · External reference
Virtual cells in a virtual microenvironment recapitulate early development-like patterns in human pluripotent stem cell colonies
10.1016/j.stemcr.2022.10.004 · 2023 · External reference
IQCELL: a platform for predicting the effect of gene perturbations on developmental trajectories using single-cell RNA-seq data
10.1371/journal.pcbi.1009907 · 2022 · External reference
A modeling framework for exploring the population-level effects of endocrine disruptors
10.1002/etc.5620170109 · 2009 · External reference
Mathematical modelling of endocrine systems
10.1016/j.tem.2019.01.008 · 2019 · External reference
SCREENED: a multistage model of thyroid gland function for screening endocrine-disrupting chemicals in a biologically sex-specific manner
10.3390/ijms21103648 · 2020 · External reference
Impact of chemical endocrine disruptors and hormone modulators on the endocrine system
10.3390/ijms23105710 · 2022 · External reference
Mathematical models in GnRH research
10.1111/jne.13085 · 2022 · External reference
In silico predictions of endocrine disruptors properties
10.1210/en.2019-00382 · 2019 · External reference
