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References from Towards advanced bioprocess optimization: A multiscale modelling approach. Local targets link to admitted publications; unresolved targets remain external evidence.
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2022 · External reference
Economic analysis of batch and continuous biopharmaceutical antibody production: a review
10.1007/s12247-018-09370-4 · 2019 · External reference
Methods for addressing host cell protein impurities in biopharmaceutical product development
10.1002/biot.202200115 · 2023 · External reference
A genome-scale nutrient minimization forecast algorithm for controlling essential amino acid levels in cho cell cultures
10.1002/bit.27994 · 2022 · External reference
Designing a strategy for ph control to improve cho cell productivity in bioreactor
2021 · External reference
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2019 · External reference
10.1016/j.csbj.2020.10.018
10.1016/j.csbj.2020.10.018 · External reference
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10.3390/metabo10080303
10.3390/metabo10080303 · External reference
10.1007/s10616-013-9648-1
10.1007/s10616-013-9648-1 · External reference
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Construction of multiscale genome-scale metabolic models: frameworks and challenges
2022 · External reference
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2009 · External reference
A reliable simulator for dynamic flux balance analysis
10.1002/bit.24748 · 2013 · External reference
Identification of a dynamic metabolic flux model for a mammalian cell culture
2019 · External reference
How reliable are chinese hamster ovary (cho) cell genome-scale metabolic models?
10.1002/bit.28366 · 2023 · External reference
Simulation and optimization of dynamic flux balance analysis models using an interior point method reformulation
10.1016/j.compchemeng.2018.08.041 · 2018 · External reference
Nonlinear model predictive control of fed-batch fermentations using dynamic flux balance models
10.1016/j.jprocont.2016.04.012 · 2016 · External reference
Analysis of control models based on dfba for fed-batch bioreactors solved by interior-point methods
2022 · External reference
Model-based optimization of antibody galactosylation in cho cell culture
10.1002/bit.26960 · 2019 · External reference
Control of igg glycosylation in cho cell perfusion cultures by greba mathematical model supported by a novel targeted feed, tafe
10.1016/j.ymben.2020.11.004 · 2021 · External reference
Quick generation of raman spectroscopy based in-?process glucose control to influence biopharmaceutical protein product quality during mammalian cell culture
2016 · External reference
Monitoring online biomass with a capacitance sensor during scale-up of industrially relevant cho cell culture fed-batch processes in single-use bioreactors
10.1007/s00449-019-02216-4 · 2019 · External reference
Increasing batch-to-batch reproducibility of cho-cell cultures using a model predictive control approach
2012 · External reference
Raman-based dynamic feeding strategies using real-time glucose concentration monitoring system during adalimumab producing cho cell cultivation
10.1002/btpr.3052 · 2020 · External reference
Process-aware data-driven modelling and model predictive control of bioreactor for the production of monoclonal antibodies
2023 · External reference
State estimation and predictive control of fed-batch cultures of hybridoma cells
10.1016/j.jprocont.2014.12.006 · 2015 · External reference
Advances in process control strategies for mammalian fed-batch cultures
10.1016/j.coche.2018.09.002 · 2018 · External reference
10.1002/bit.26384
10.1002/bit.26384 · External reference
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Advanced model-based control strategies for the intensification of upstream and downstream processing in mab production
10.1002/btpr.2483 · 2017 · External reference
Pid controls: the forgotten bioprocess parameters
10.1007/s43938-022-00008-z · 2022 · External reference
A framework for the systematic design of fed-batch strategies in mammalian cell culture
10.1002/bit.25319 · 2014 · External reference
10.1101/2021.07.19.452953
10.1101/2021.07.19.452953 · External reference
Review on model predictive control: an engineering perspective
10.1007/s00170-021-07682-3 · 2021 · External reference
On the “bang-bang” control problem
10.1090/qam/78516 · 1956 · External reference
Nonlinear mpc for fed-batch multiple stages sugar crystallization
10.1016/j.cherd.2010.10.010 · 2011 · External reference
A method for handling batch-to-batch parametric drift using moving horizon estimation: Application to run-to-run mpc of batch crystallization
2015 · External reference
Process-aware data-driven modelling and model predictive control of bioreactor for the production of monoclonal antibodies
10.1002/cjce.24752 · 2023 · External reference
Modeling amino acid metabolism in mammalian cells-toward the development of a model library
10.1021/bp070106z · 2007 · External reference
Effects of nutrient levels and average culture ph on the glycosylation pattern of camelid-humanized monoclonal antibody
10.1016/j.jbiotec.2014.05.024 · 2014 · External reference
Effects of elevated pco2 and osmolality on growth of cho cells and production of antibody-fusion protein b1: a case study
2005 · External reference
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Systematic development of predictive mathematical models for animal cell cultures
10.1016/j.compchemeng.2010.03.012 · 2010 · External reference
Comparative analysis of amino acid metabolism and transport in cho variants with different levels of productivity
10.1016/j.jbiotec.2013.09.007 · 2013 · External reference
Computational approach for understanding and improving gs-ns0 antibody production under hyperosmotic conditions
10.1016/j.jbiosc.2011.08.022 · 2012 · External reference