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References from An integrated analysis of dysregulated SCD1 in human cancers and functional verification of miR-181a-5p/SCD1 axis in esophageal squamous cell carcinoma. Local targets link to admitted publications; unresolved targets remain external evidence.
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Novel long noncoding RNA LINC02820 augments TNF signaling pathway to remodel cytoskeleton and potentiate metastasis in esophageal squamous cell carcinoma
2022 · External reference
MEX3A is upregulated in esophageal squamous cell carcinoma (ESCC) and promotes development and progression of ESCC through targeting CDK6
10.18632/aging.103196 · 2020 · External reference
Azelnidipine inhibits esophageal squamous cell carcinoma proliferation in vivo and in vitro by targeting MEK1/2
10.1016/j.omto.2022.09.007 · 2022 · External reference
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10.1093/annonc/mdy011 · External reference
Lipid metabolism in cancer: A systematic review
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10.1186/s13046-021-02067-6
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Targeting stearoyl-coa desaturase enhances radiation induced ferroptosis and immunogenic cell death in esophageal squamous cell carcinoma
10.1080/2162402x.2022.2101769 · 2022 · External reference
10.1016/j.cbi.2019.108917
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Insights into Stearoyl-CoA Desaturase-1 regulation of systemic metabolism
10.1016/j.tem.2017.10.003 · 2017 · External reference
Stearoyl-CoA desaturase-1 promotes colorectal cancer metastasis in response to glucose by suppressing PTEN
10.1186/s13046-018-0711-9 · 2018 · External reference
Stearoyl-CoA Desaturase 1 as a therapeutic target for the treatment of cancer
10.3390/cancers11070948 · 2019 · External reference
10.1007/s11033-021-07094-2
10.1007/s11033-021-07094-2 · External reference
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10.1126/sciadv.abd7459 · External reference
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10.1038/nrd.2016.246 · External reference
10.1016/j.cca.2022.10.018
10.1016/j.cca.2022.10.018 · External reference
MicroRNAs in the pathogenesis of hepatocellular carcinoma: a review
10.3390/cancers13030514 · 2021 · External reference
Aberrant miR-874-3p/leptin/EGFR/c-Myc signaling contributes to nasopharyngeal carcinoma pathogenesis
10.1186/s13046-022-02415-0 · 2022 · External reference
DRP1 contributes to head and neck cancer progression and induces glycolysis through modulated FOXM1/MMP12 axis
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10.1016/j.canlet.2016.12.033
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Highly-metastatic colorectal cancer cell released miR-181a-5p-rich extracellular vesicles promote liver metastasis by activating hepatic stellate cells and remodelling the tumour microenvironment
10.1002/jev2.12186 · 2022 · External reference
10.18632/aging.204028
10.18632/aging.204028 · External reference
microRNA-181a-5p impedes the proliferation, migration, and invasion of retinoblastoma cells by targeting the NRAS proto-oncogene
10.1016/j.clinsp.2022.100026 · 2022 · External reference
p73alpha1, an isoform of the p73 tumor suppressor, modulates lipid metabolism and cancer cell growth via Stearoyl-CoA Desaturase-1
10.3390/cells11162516 · 2022 · External reference
Unsaturated fatty acids promote hepatoma proliferation and progression through downregulation of the tumor suppressor PTEN
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10.1038/onc.2016.53 · External reference
10.1158/0008-5472.can-19-0369
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10.1038/ijo.2014.35
10.1038/ijo.2014.35 · External reference
10.1515/bc.2007.046
10.1515/bc.2007.046 · External reference
Stearoyl CoA desaturase regulates ferroptosis in ovarian cancer offering new therapeutic perspectives
10.1158/0008-5472.can-19-2453 · 2019 · External reference
10.1016/j.redox.2020.101807
10.1016/j.redox.2020.101807 · External reference
10.1007/s11010-021-04167-5
10.1007/s11010-021-04167-5 · External reference
Stearoyl-CoA-desaturase 1 regulates lung cancer stemness via stabilization and nuclear localization of YAP/TAZ
10.1038/onc.2017.75 · 2017 · External reference
SCD1 is required for EGFR-targeting cancer therapy of lung cancer via re-activation of EGFR/PI3K/AKT signals
10.1186/s12935-019-0809-y · 2019 · External reference
EGFR modulates monounsaturated fatty acid synthesis through phosphorylation of SCD1 in lung cancer
10.1186/s12943-017-0704-x · 2017 · External reference
10.1073/pnas.1409778111
10.1073/pnas.1409778111 · External reference
10.1016/j.cmet.2019.07.012
10.1016/j.cmet.2019.07.012 · External reference
KRAS affects adipogenic differentiation by regulating autophagy and MAPK activation in 3T3-L1 and C2C12 cells
2021 · External reference
10.1073/pnas.1617709114
10.1073/pnas.1617709114 · External reference
Inhibition of stearoyl CoA desaturase-1 activity suppresses tumour progression and improves prognosis in human bladder cancer
10.1111/jcmm.14114 · 2019 · External reference
Targeting stearoyl-CoA desaturase 1 to repress endometrial cancer progression
10.18632/oncotarget.24304 · 2018 · External reference
Stearoyl-CoA desaturase-1 mediated cell apoptosis in colorectal cancer by promoting ceramide synthesis
10.1038/srep19665 · 2016 · External reference
Carcinoma-associated fibroblasts release microRNA-331-3p containing extracellular vesicles to exacerbate the development of pancreatic cancer via the SCARA5-FAK axis
10.1080/15384047.2022.2041961 · 2022 · External reference
MicroRNAs in esophageal squamous cell carcinoma: Application in prognosis, diagnosis, and drug delivery
10.1016/j.prp.2022.154196 · 2022 · External reference
MicroRNA Expression Profiles in Superficial Esophageal Squamous Cell Carcinoma before Endoscopic Submucosal Dissection: A Pilot Study
10.3390/ijms22094789 · 2021 · External reference
Development and validation of an esophageal squamous cell carcinoma detection model by large-scale MicroRNA profiling
10.1001/jamanetworkopen.2019.4573 · 2019 · External reference
LncRNA LUCAT1/miR-181a-5p axis promotes proliferation and invasion of breast cancer via targeting KLF6 and KLF15
10.1186/s12860-020-00310-0 · 2020 · External reference
Discovery of extracellular vesicles derived miR-181a-5p in patient's serum as an indicator for bone-metastatic prostate cancer
10.7150/thno.49186 · 2021 · External reference
LncRNA LHFPL3-AS1 contributes to tumorigenesis of melanoma stem cells via the miR-181a-5p/BCL2 pathway
10.1038/s41419-020-03141-1 · 2020 · External reference
MiR-181a-5p facilitates proliferation, invasion, and glycolysis of breast cancer through NDRG2-mediated activation of PTEN/AKT pathway
10.1080/21655979.2021.2006974 · 2022 · External reference
miR-181a-5p is downregulated and inhibits proliferation and the cell cycle in prostate cancer
2018 · External reference
miR-181a-5p, an inducer of Wnt-signaling, facilitates cell proliferation in acute lymphoblastic leukemia
10.3892/or.2017.5425 · 2017 · External reference
MicroRNA-181a-5p enhances cell proliferation in medullary thymic epithelial cells via regulating TGF-beta signaling.
10.1093/abbs/gmw068 · 2016 · External reference
Regulatory Interplay between miR-181a-5p and Estrogen Receptor Signaling Cascade in Breast Cancer
10.3390/cancers13030543 · 2021 · External reference
Overexpression of miR-181a-5p inhibits retinal neovascularization through endocan and the ERK1/2 signaling pathway
10.1002/jcp.29733 · 2020 · External reference
MicroRNA-181a promotes angiogenesis in colorectal cancer by targeting SRCIN1 to promote the SRC/VEGF signaling pathway
10.1038/s41419-018-0490-4 · 2018 · External reference
TCL1A acts as a tumour suppressor by modulating gastric cancer autophagy via miR-181a-5p-TCL1A-Akt/mTOR-c-MYC loop
10.1093/carcin/bgac085 · 2023 · External reference
Oncogenic activation of PI3K-AKT-mTOR signaling suppresses ferroptosis via SREBP-mediated lipogenesis
10.1073/pnas.2017152117 · 2020 · External reference
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10.1172/jci95864 · External reference
