Research graph
References from Hybrid computational modeling highlights reverse warburg effect in breast cancer-associated fibroblasts. Local targets link to admitted publications; unresolved targets remain external evidence.
Unresolved reference
2022 · External reference
10.1002/path.1398
10.1002/path.1398 · External reference
The clinical role of the TME in solid cancer
10.1038/s41416-018-0327-z · 2018 · External reference
10.3390/cancers13092053
10.3390/cancers13092053 · External reference
Effect of stromal cells in tumor microenvironment on metastasis initiation
10.7150/ijbs.25720 · 2018 · External reference
10.3390/cancers13184720
10.3390/cancers13184720 · External reference
The role of cancer-associated fibroblasts in tumor progression
10.3390/cancers13061399 · 2021 · External reference
10.1038/s41417-021-00318-4
10.1038/s41417-021-00318-4 · External reference
Fibroblast heterogeneity and immunosuppressive environment in human breast cancer
10.1016/j.ccell.2018.01.011 · 2018 · External reference
10.3390/cancers13010035
10.3390/cancers13010035 · External reference
10.1085/jgp.8.6.519
10.1085/jgp.8.6.519 · External reference
10.4161/cc.8.23.10238
10.4161/cc.8.23.10238 · External reference
10.1038/oncsis.2015.19
10.1038/oncsis.2015.19 · External reference
CAF heterogeneity and dynamics
10.1038/s41556-022-01054-z · 2022 · External reference
Unresolved reference
2021 · External reference
10.1016/j.csbj.2022.06.035
10.1016/j.csbj.2022.06.035 · External reference
10.1016/0022-5193(69)90015-0
10.1016/0022-5193(69)90015-0 · External reference
A comparative study of qualitative and quantitative dynamic models of biological regulatory networks
2016 · External reference
10.3390/pr9020322
10.3390/pr9020322 · External reference
10.1073/pnas.1005139107
10.1073/pnas.1005139107 · External reference
FlexFlux: combining metabolic flux and regulatory network analyses
2015 · External reference
Regulatory dynamic enzyme-cost flux balance analysis: A unifying framework for constraint-based modeling
10.1016/j.jtbi.2020.110317 · 2020 · External reference
Metabolic reprogramming in Rheumatoid Arthritis Synovial Fibroblasts: A hybrid modeling approach
10.1371/journal.pcbi.1010408 · 2022 · External reference
10.1371/journal.pcbi.1004571
10.1371/journal.pcbi.1004571 · External reference
Computational modelling of drug delivery to solid tumour: Understanding the interplay between chemotherapeutics and biological system for optimised delivery systems
10.1016/j.addr.2018.07.013 · 2018 · External reference
Unresolved reference
2020 · External reference
Hybrid modeling frameworks of tumor development and treatment
2019 · External reference
10.3322/caac.21660
10.3322/caac.21660 · External reference
Unresolved reference
External reference
10.1038/nbt.1558
10.1038/nbt.1558 · External reference
Unresolved reference
2003 · External reference
The FAIR Guiding Principles for scientific data management and stewardship. Scientific
2016 · External reference
10.1093/nar/28.1.27
10.1093/nar/28.1.27 · External reference
Unresolved reference
2009 · External reference
Systems biology graphical notation: process description language level 1
2011 · External reference
Genenames.org: the HGNC resources in 2023
2022 · External reference
BiGG Models: A platform for integrating, standardizing and sharing genome-scale models
10.1093/nar/gkv1049 · 2015 · External reference
Minimum information requested in the annotation of biochemical models (MIRIAM)
10.1038/nbt1156 · 2005 · External reference
Setting the basis of best practices and standards for curation and annotation of logical models in biology—highlights of the [BC]2 2019 CoLoMoTo/SysMod Workshop
10.1093/bib/bbaa046 · 2020 · External reference
MINERVA—a platform for visualization and curation of molecular interaction networks
2016 · External reference
10.1093/bioinformatics/btaa484
10.1093/bioinformatics/btaa484 · External reference
SBML qualitative models: a model representation format and infrastructure to foster interactions between qualitative modelling formalisms and tools
10.1186/1752-0509-7-135 · 2013 · External reference
10.1186/1752-0509-6-96
10.1186/1752-0509-6-96 · External reference
The European Genome-phenome Archive in 2021
2021 · External reference
A subset of activated fibroblasts is associated with distant relapse in early luminal breast cancer
2020 · External reference
limma powers differential expression analyses for RNA-sequencing and microarray studies
10.1093/nar/gkv007 · 2015 · External reference
PANTHER version 14: more genomes, a new PANTHER GO-slim and improvements in enrichment analysis tools
10.1093/nar/gky1038 · 2018 · External reference
An effective network reduction approach to find the dynamical repertoire of discrete dynamic networks. Chaos: An Interdisciplinary
2013 · External reference
Unresolved reference
2014 · External reference
BioLQM: A Java Toolkit for the Manipulation and Conversion of Logical Qualitative Models of Biological Networks
2018 · External reference
MitoCore: a curated constraint-based model for simulating human central metabolism
2017 · External reference
Computational Verification of Large Logical Models—Application to the Prediction of T Cell Response to Checkpoint Inhibitors
2020 · External reference
The CoLoMoTo interactive notebook: accessible and reproducible computational analyses for qualitative biological networks
2018 · External reference
10.1038/nbt.1614
10.1038/nbt.1614 · External reference
COBRApy: COnstraints-based reconstruction and analysis for python
2013 · External reference
10.3390/cancers13133146
10.3390/cancers13133146 · External reference
MMP-2 and MMP-9 Expression in Breast Cancer-Derived Human Fibroblasts is Differentially Regulated by Stromal-Epithelial Interactions
10.1023/a:1014918512569 · 2002 · External reference
Interleukins associated with breast cancer
10.7759/cureus.3549 · 2018 · External reference
HIF1-alpha functions as a tumor promoter in cancer-associated fibroblasts, and as a tumor suppressor in breast cancer cells
10.4161/cc.9.17.12908 · 2010 · External reference
10.1016/s0092-8674(00)81731-6
10.1016/s0092-8674(00)81731-6 · External reference
Unresolved reference
2020 · External reference
Role of tumor-derived fibroblasts in the growth of primary cultures of human breast-cancer cells: Effects of epidermal growth factor and the somatostatin analogue octreotide
10.1002/ijc.2910600114 · 1995 · External reference
Fibrotic activity quantified in serum by measurements of type III collagen pro-peptides can be used for prognosis across different solid tumor types
2022 · External reference
10.1016/j.ajpath.2020.06.008
10.1016/j.ajpath.2020.06.008 · External reference
‘Reverse Warburg effect’ of cancer‑associated fibroblasts (Review)
2022 · External reference
The role of hypoxia in cancer progression, angiogenesis, metastasis, and resistance to therapy
10.2147/hp.s93413 · 2015 · External reference
10.3390/cancers14143321
10.3390/cancers14143321 · External reference
10.1126/science.123.3191.309
10.1126/science.123.3191.309 · External reference
The Warburg hypothesis fifty years later. Zeitschrift Für Krebsforschung Und Klinische
1976 · External reference
Hypoxia-Inducible Factor (HIF) as a Target for Novel Therapies in Rheumatoid Arthritis
2016 · External reference
Targeting hypoxia-inducible factors for breast cancer therapy: A narrative review
2022 · External reference
Honokiol Inhibits HIF-1α-Mediated Glycolysis to Halt Breast Cancer Growth
2022 · External reference
Deferiprone Stimulates Aged Dermal Fibroblasts via HIF-1α Modulation
10.1093/asj/sjaa142 · 2020 · External reference
Targeting Hypoxia Inducible Factors-1α As a Novel Therapy in Fibrosis
2017 · External reference
