Research graph
References from Computer-assisted stabilization of fibroblast growth factor FGF-18. Local targets link to admitted publications; unresolved targets remain external evidence.
New developments in the biology of fibroblast growth factors
10.1002/wsbm.1549 · 2022 · External reference
10.1038/nrc2780
10.1038/nrc2780 · External reference
Fibroblast growth factors: biology, function, and application for tissue regeneration
2010 · External reference
10.1002/wdev.176
10.1002/wdev.176 · External reference
10.1038/nrd2792
10.1038/nrd2792 · External reference
Palifermin for oral mucositis after intensive therapy for hematologic cancers
10.1056/nejmoa040125 · 2004 · External reference
10.1016/j.ydbio.2006.08.071
10.1016/j.ydbio.2006.08.071 · External reference
Role of FGF-18 in bone regeneration
10.3390/jfb14010036 · 2023 · External reference
A review of FGF18: its expression, signaling pathways and possible functions during embryogenesis and post-natal development
2007 · External reference
10.1016/j.phrs.2018.09.026
10.1016/j.phrs.2018.09.026 · External reference
10.1016/s0140-6736(16)31678-6
10.1016/s0140-6736(16)31678-6 · External reference
10.1002/art.42089
10.1002/art.42089 · External reference
Effect of intra-articular sprifermin vs placebo on femorotibial joint cartilage thickness in patients with osteoarthritis: the FORWARD randomized clinical trial
10.1001/jama.2019.14735 · 2019 · External reference
A first-in-human, double-blind, randomised, placebo-controlled, dose ascending study of intra-articular RhFGF18 (Sprifermin) in patients with advanced knee osteoarthritis
2016 · External reference
Intraarticular sprifermin (recombinant human fibroblast growth factor 18) in knee osteoarthritis: a randomized, double-blind, placebo-controlled trial
10.1002/art.38614 · 2014 · External reference
Instability restricts signaling of multiple fibroblast growth factors
10.1007/s00018-015-1856-8 · 2015 · External reference
10.1002/bit.26531
10.1002/bit.26531 · External reference
FireProt: energy- and evolution-based computational design of thermostable multiple-point mutants
10.1371/journal.pcbi.1004556 · 2015 · External reference
Tissue distribution of sprifermin (recombinant human fibroblast Growth Factor 18) in the rat following intravenous and intra-articular injection
10.1016/j.ocarto.2020.100068 · 2020 · External reference
10.1093/nar/gky1069
10.1093/nar/gky1069 · External reference
10.1093/bioinformatics/btl158
10.1093/bioinformatics/btl158 · External reference
CLANS: a java application for visualizing protein families based on pairwise similarity
10.1093/bioinformatics/bth444 · 2004 · External reference
MUSCLE: a multiple sequence alignment method with reduced time and space complexity
2004 · External reference
The crystal structure of fibroblast growth factor 18 (FGF18
10.1007/s13238-014-0033-4 · 2014 · External reference
The FoldX web server: an online force Field
10.1093/nar/gki387 · 2005 · External reference
10.1021/acs.jctc.7b00125
10.1021/acs.jctc.7b00125 · External reference
Role of conformational sampling in computing mutation-induced changes in protein structure and stability
10.1002/prot.22921 · 2011 · External reference
10.1093/nar/gkw408
10.1093/nar/gkw408 · External reference
Fibroblast growth factor 2 protein stability provides decreased dependence on heparin for induction of FGFR signaling and alters ERK signaling dynamics
2019 · External reference
10.1074/jbc.271.25.15292
10.1074/jbc.271.25.15292 · External reference
Protein identification and analysis tools on the ExPASy server
10.1385/1-59259-890-0:571 · 2005 · External reference
Advancing enzyme’s stability and catalytic efficiency through synergy of force-field calculations, evolutionary analysis, and machine learning
10.1021/acscatal.3c02575 · 2023 · External reference
10.1074/jbc.m601252200
10.1074/jbc.m601252200 · External reference
Sprifermin treatment enhances cartilage integration in an in vitro repair model
10.1002/jor.24048 · 2018 · External reference
Sprifermin (RhFGF18) modulates extracellular matrix turnover in cartilage explants ex vivo
10.1186/s12967-017-1356-8 · 2017 · External reference
The recombinant human fibroblast growth factor-18 (Sprifermin) improves tendon-to-bone healing by promoting chondrogenesis in a rat rotator cuff repair model
10.1016/j.jse.2022.01.137 · 2022 · External reference
Sprifermin (RhFGF18) enables proliferation of chondrocytes producing a hyaline cartilage matrix
10.1016/j.joca.2017.08.004 · 2017 · External reference
Long-term structural and symptomatic effects of intra-articular sprifermin in patients with knee osteoarthritis: 5-year results from the FORWARD study
10.1136/annrheumdis-2020-219181 · 2021 · External reference
