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References from Using graph-based model to identify cell specific synthetic lethal effects. Local targets link to admitted publications; unresolved targets remain external evidence.
10.1126/science.123.3191.309
10.1126/science.123.3191.309 · External reference
Computational methods, databases and tools for synthetic lethality prediction
10.1093/bib/bbac106 · 2022 · External reference
Advances in synthetic lethality for cancer therapy: cellular mechanism and clinical translation
10.1186/s13045-020-00956-5 · 2020 · External reference
10.1038/s41571-018-0055-6
10.1038/s41571-018-0055-6 · External reference
Mechanisms of PARP inhibitor sensitivity and resistance
10.1016/j.dnarep.2018.08.021 · 2018 · External reference
10.1038/nature03443
10.1038/nature03443 · External reference
10.1038/nrc.2015.21
10.1038/nrc.2015.21 · External reference
10.1038/nature03445
10.1038/nature03445 · External reference
10.1158/1541-7786.mcr-18-0860
10.1158/1541-7786.mcr-18-0860 · External reference
10.1038/s41568-018-0034-3
10.1038/s41568-018-0034-3 · External reference
Development of synthetic lethality in cancer: molecular and cellular classification
10.1038/s41392-020-00358-6 · 2020 · External reference
10.1146/annurev-cancerbio-030419-033444
10.1146/annurev-cancerbio-030419-033444 · External reference
10.1016/j.cell.2014.07.027
10.1016/j.cell.2014.07.027 · External reference
Dual-dropout graph convolutional network for predicting synthetic lethality in human cancers
10.1093/bioinformatics/btaa211 · 2020 · External reference
EXP2SL: a machine learning framework for cell-line-specific synthetic lethality prediction
10.3389/fphar.2020.00112 · 2020 · External reference
Comprehensive prediction of robust synthetic lethality between paralog pairs in cancer cell lines
2021 · External reference
10.1093/bioinformatics/btab110
10.1093/bioinformatics/btab110 · External reference
Predicting synthetic lethal interactions in human cancers using graph regularized self-representative matrix factorization
10.1186/s12859-019-3197-3 · 2019 · External reference
SL 2 MF: predicting synthetic lethality in human cancers via logistic matrix factorization
10.1109/tcbb.2019.2909908 · 2020 · External reference
NSF4SL: negative-sample-free contrastive learning for ranking synthetic lethal partner genes in human cancers
10.1093/bioinformatics/btac462 · 2022 · External reference
10.1093/bioinformatics/btab271
10.1093/bioinformatics/btab271 · External reference
Unresolved reference
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10.1109/embc46164.2021.9630716
10.1109/embc46164.2021.9630716 · External reference
Unresolved reference
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Prediction of synthetic lethal interactions in human cancers using multi-view graph auto-encoder
10.1109/jbhi.2021.3079302 · 2021 · External reference
10.1126/sciadv.abc2100
10.1126/sciadv.abc2100 · External reference
Multi-view graph convolutional network for cancer cell-specific synthetic lethality prediction
10.3389/fgene.2022.1103092 · 2023 · External reference
10.1016/j.cell.2017.10.049
10.1016/j.cell.2017.10.049 · External reference
CRISPR/Cas9-mediated gene modification and gene knock out in the human-infective parasite Trichomonas vaginalis
10.1038/s41598-017-18442-3 · 2018 · External reference
10.1038/s41467-018-06916-5
10.1038/s41467-018-06916-5 · External reference
10.1038/ng.3984
10.1038/ng.3984 · External reference
10.1038/s41586-019-1103-9
10.1038/s41586-019-1103-9 · External reference
Extracting biological insights from the project achilles genome-scale CRISPR screens in cancer cell lines
10.1101/720243 · 2019 · External reference
WeSME: uncovering mutual exclusivity of cancer drivers and beyond
10.1093/bioinformatics/btw242 · 2017 · External reference
GEMINI: a variational Bayesian approach to identify genetic interactions from combinatorial CRISPR screens
10.1186/s13059-019-1745-9 · 2019 · External reference
10.1016/j.molcel.2018.01.017
10.1016/j.molcel.2018.01.017 · External reference
10.1186/s13059-020-02173-2
10.1186/s13059-020-02173-2 · External reference
10.1038/s41588-021-00967-z
10.1038/s41588-021-00967-z · External reference
10.1038/nbt.4048
10.1038/nbt.4048 · External reference
Unresolved reference
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Unresolved reference
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Topology Adaptive Graph Convolutional
2017 · External reference
10.1038/s41467-020-14620-6
10.1038/s41467-020-14620-6 · External reference
Functional interaction between PARP-1 and PARP-2 in chromosome stability and embryonic development in mouse
10.1093/emboj/cdg206 · 2003 · External reference
10.1016/j.ebiom.2020.102988
10.1016/j.ebiom.2020.102988 · External reference
Combined inhibition of Wee1 and PARP1/2 for radiosensitization in pancreatic cancer
10.1158/1078-0432.ccr-14-1038 · 2014 · External reference
10.1158/1541-7786.mcr-17-0455
10.1158/1541-7786.mcr-17-0455 · External reference
RHOA therapeutic targeting in hematological cancers
10.3390/cells12030433 · 2023 · External reference
WEE1 inhibition enhances anti-apoptotic dependency as a result of premature mitotic entry and DNA damage
10.3390/cancers11111743 · 2019 · External reference
Knockdown of STIL suppresses the progression of gastric cancer by down‐regulating the IGF‐1/PI3K/AKT pathway
10.1111/jcmm.14440 · 2019 · External reference
Paralog dispensability shapes homozygous deletion patterns in tumor genomes
10.1101/2022.06.20.496722 · 2022 · External reference
10.1016/j.trecan.2023.02.002
10.1016/j.trecan.2023.02.002 · External reference
Paralog-based synthetic lethality: rationales and applications
10.3389/fonc.2023.1168143 · 2023 · External reference
10.1016/j.trecan.2021.04.009
10.1016/j.trecan.2021.04.009 · External reference
10.1016/j.celrep.2022.110636
10.1016/j.celrep.2022.110636 · External reference
10.1158/0008-5472.can-21-4443
10.1158/0008-5472.can-21-4443 · External reference
10.1038/s41594-023-01041-4
10.1038/s41594-023-01041-4 · External reference