Research graph
References from Network-based drug repurposing for HPV-associated cervical cancer. Local targets link to admitted publications; unresolved targets remain external evidence.
Global Cancer Statistics 2020: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries
2021 · External reference
Sexual behaviour and risk factors for the acquisition of human papillomavirus infections in young people in Italy: suggestions for future vaccination policies
10.1186/1471-2458-12-623 · 2012 · External reference
Biology of human papillomavirus infection and immune therapy for HPV-related head and neck cancers
10.1016/j.otc.2012.04.005 · 2012 · External reference
Targeting persistent human papillomavirus infection
10.3390/v9080229 · 2017 · External reference
HIV-positive women have higher risk of human papilloma virus infection, precancerous lesions, and cervical cancer
10.1097/qad.0000000000001765 · 2018 · External reference
Update on prevention and screening of cervical cancer
10.5306/wjco.v5.i4.744 · 2014 · External reference
The precision prevention and therapy of HPV-related cervical cancer: new concepts and clinical implications
10.1002/cam4.1501 · 2018 · External reference
Human papillomavirus vaccine against cervical cancer: opportunity and challenge
10.1016/j.canlet.2019.11.039 · 2020 · External reference
Drug repurposing in psoriasis, performed by reversal of disease-associated gene expression profiles
10.1016/j.csbj.2022.10.046 · 2022 · External reference
Drug repurposing in cancer therapy: influence of patient’s genetic background in breast cancer treatment
10.3390/ijms23084280 · 2022 · External reference
Drug repurposing against breast cancer by integrating drug-exposure expression profiles and drug–drug links based on graph neural network
10.1093/bioinformatics/btab191 · 2021 · External reference
Drug repurposing: a systematic review on root causes, barriers and facilitators
10.1186/s12913-022-08272-z · 2022 · External reference
SperoPredictor: an integrated machine learning and molecular docking-based drug repurposing framework with use case of COVID-19
2022 · External reference
Cervical cancer therapies: current challenges and future perspectives
10.1016/j.tvr.2022.200238 · 2022 · External reference
An overview of novel agents for cervical cancer treatment by inducing apoptosis: emerging drugs ongoing clinical trials and preclinical studies
2021 · External reference
Artificial intelligence-assisted repurposing of lubiprostone alleviates tubulointerstitial fibrosis
10.1016/j.trsl.2023.07.010 · 2023 · External reference
A systematic review of computational approaches to understand cancer biology for informed drug repurposing
10.1016/j.jbi.2023.104373 · 2023 · External reference
A comprehensive review of key factors affecting the efficacy of antibody drug conjugate
10.1016/j.biopha.2023.114408 · 2023 · External reference
Metformin and cervical cancer risk in patients with newly diagnosed type 2 diabetes: a population-based study in Korea
10.3803/enm.2022.1613 · 2022 · External reference
Synergistic effects of thalidomide and cisplatin are mediated via the PI3K/AKT and JAK1/STAT3 signaling pathways in cervical cancer
2022 · External reference
Drug repurposing as a potential source of innovative therapies in cervical cancer
10.1136/ijgc-2022-003585 · 2022 · External reference
Immune checkpoint inhibitors in cancer therapy
10.3390/curroncol29050247 · 2022 · External reference
Chasing immune checkpoint inhibitors in ovarian cancer: novel combinations and biomarker discovery
10.3390/cancers15123220 · 2023 · External reference
Drug repurposing for glioblastoma based on molecular subtypes
10.1016/j.jbi.2016.09.019 · 2016 · External reference
Molecular docking based virtual screening of the breast cancer target NUDT5
10.6026/97320630015784 · 2019 · External reference
Artificial intelligence and machine learning in cancer imaging
10.1038/s43856-022-00199-0 · 2022 · External reference
Machine learning-based virtual screening and its applications to Alzheimer’s drug discovery: a review
10.2174/1381612824666180607124038 · 2018 · External reference
Machine learning classification can reduce false positives in structure-based virtual screening
10.1073/pnas.2000585117 · 2020 · External reference
A network medicine approach for identifying diagnostic and prognostic biomarkers and exploring drug repurposing in human cancer
10.1016/j.csbj.2022.11.037 · 2023 · External reference
Network-based drug repurposing for novel coronavirus 2019-nCoV/SARS-CoV-2
10.1038/s41421-020-0153-3 · 2020 · External reference
Identification of SARS-CoV-2–induced pathways reveals drug repurposing strategies
2021 · External reference
A comprehensive review of artificial intelligence and network based approaches to drug repurposing in Covid-19
10.1016/j.biopha.2022.113350 · 2022 · External reference
Drug repurposing: re-inventing therapies for cancer without re-entering the development pipeline—a review
2022 · External reference
Drug Repurposing for viral cancers: a paradigm of machine learning, deep learning, and Virtual screening-based approaches
2023 · External reference
The Ensembl genome database project
10.1093/nar/30.1.38 · 2002 · External reference
UniProt: the universal protein knowledgebase in 2021
10.1093/nar/gkaa1100 · 2021 · External reference
Multi-infection patterns and co-infection preference of 27 human papillomavirus types among 137,943 gynecological outpatients across China
10.3389/fonc.2020.00449 · 2020 · External reference
Microphysiological system with continuous analysis of albumin for hepatotoxicity modeling and drug screening
10.1016/j.jiec.2021.03.035 · 2021 · External reference
Yeast two-hybrid, a powerful tool for systems biology
10.3390/ijms10062763 · 2009 · External reference
Gene expression omnibus: NCBI gene expression and hybridization array data repository
10.1093/nar/30.1.207 · 2002 · External reference
Unresolved reference
External reference
Gene ontology: tool for the unification of biology
10.1038/75556 · 2000 · External reference
ShinyGO: a graphical gene-set enrichment tool for animals and plants
10.1093/bioinformatics/btz931 · 2020 · External reference
The DAVID gene functional classification tool: a novel biological module-centric algorithm to functionally analyze large gene lists
10.1186/gb-2007-8-9-r183 · 2007 · External reference
g:Profiler: a web server for functional enrichment analysis and conversions of gene lists (2019 update)
10.1093/nar/gkz369 · 2019 · External reference
The STRING database in 2023: protein–protein association networks and functional enrichment analyses for any sequenced genome of interest
10.1093/nar/gkac1000 · 2023 · External reference
The sumatriptan/naratriptan aggregated patient (SNAP) database: aggregation, validation and application
10.1111/j.1468-2982.2003.00722.x · 2004 · External reference
DisGeNET: a comprehensive platform integrating information on human disease-associated genes and variants
10.1093/nar/gkw943 · 2017 · External reference
Construction and analysis of protein-protein interaction network of heroin use disorder
10.1038/s41598-019-41552-z · 2019 · External reference
Biclique extension as an effective approach to identify missing links in metabolic compound–protein interaction networks
10.1093/bioadv/vbac001 · 2022 · External reference
The multi-point delivery problem: shortest path algorithm for real roads network using Dijkstra
10.1088/1742-6596/1530/1/012040 · 2020 · External reference
Unresolved reference
External reference
10.1609/icwsm.v3i1.13937
10.1609/icwsm.v3i1.13937 · External reference
Designing a network proximity-based drug repurposing strategy for COVID-19
10.3389/fcell.2020.545089 · 2020 · External reference
RWRNET: a gene regulatory network inference algorithm using random walk with restart
10.3389/fgene.2020.591461 · 2020 · External reference
Permutation and randomization tests for network analysis
10.1016/j.socnet.2019.08.001 · 2019 · External reference
Inferring the perturbed microRNA regulatory networks from gene expression data using a network propagation based method
10.1186/1471-2105-15-255 · 2014 · External reference
DrugBank: a comprehensive resource for in silico drug discovery and exploration
10.1093/nar/gkj067 · 2006 · External reference
ChEMBL: a large-scale bioactivity database for drug discovery
10.1093/nar/gkr777 · 2012 · External reference
Cancer based pharmacogenomics network supported with scientific evidences: from the view of drug repurposing
10.1186/s13040-015-0042-8 · 2015 · External reference
Therapeutic target database update 2022: facilitating drug discovery with enriched comparative data of targeted agents
10.1093/nar/gkab953 · 2022 · External reference
Gene set enrichment analysis: a knowledge-based approach for interpreting genome-wide expression profiles
10.1073/pnas.0506580102 · 2005 · External reference
Statistically controlled identification of differentially expressed genes in one-to-one cell line comparisons of the CMAP database for drug repositioning
10.1186/s12967-017-1302-9 · 2017 · External reference
The drug repurposing hub: a next-generation drug library and information resource
10.1038/nm.4306 · 2017 · External reference
Decade of bio-inspired soft robots: a review
10.1088/1361-665x/ac6e15 · 2022 · External reference
Multi-material bio-inspired soft octopus robot for underwater synchronous swimming
10.1007/s42235-022-00208-x · 2022 · External reference
Network-based prediction of drug combinations
10.1038/s41467-019-09692-y · 2019 · External reference
Identification of core prognosis-related candidate genes in cervical cancer via integrated bioinformatical analysis
10.1155/2020/8959210 · 2020 · External reference
Diagnosis of cervical cancer and pre-cancerous lesions by artificial intelligence: a systematic review
2022 · External reference
GRAND: a large-scale dataset and benchmark for cervical intraepithelial Neoplasia grading with fine-grained lesion description
10.1016/j.media.2021.102006 · 2021 · External reference
Human papillomavirus-associated cancers: a growing global problem
10.4103/2229-516x.179027 · 2016 · External reference
Gene expression profiles and pathway enrichment analysis of human osteosarcoma cells exposed to sorafenib
10.1002/2211-5463.12428 · 2018 · External reference
Human papillomavirus and cervical cancer
10.1016/s0140-6736(07)61416-0 · 2007 · External reference
SNX10 and PTGDS are associated with the progression and prognosis of cervical squamous cell carcinoma
10.1186/s12885-021-08212-w · 2021 · External reference
Vorinostat, a pan-HDAC inhibitor, abrogates productive HPV-18 DNA amplification
10.1073/pnas.1801156115 · 2018 · External reference
Improved survival with bevacizumab in advanced cervical cancer
10.1056/nejmoa1309748 · 2014 · External reference
Effect of statin on risk of gynecologic cancers: a meta-analysis of observational studies and randomized controlled trials
10.1016/j.ygyno.2014.04.007 · 2014 · External reference
Etomidate inhibits cell proliferation and induces apoptosis in A549 non-small cell lung cancer cells via downregulating WWP2
10.3892/etm.2021.10689 · 2021 · External reference
Practical guide for using methadone in pain and palliative care practice
10.4103/ijpc.ijpc_186_17 · 2018 · External reference
Risk of cancer in long-term levothyroxine users: retrospective population-based study
10.1111/cas.14908 · 2021 · External reference
ReDO_DB: the repurposing drugs in oncology database
10.3332/ecancer.2018.886 · 2018 · External reference
