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References from Peritendinous adhesion: Therapeutic targets and progress of drug therapy. Local targets link to admitted publications; unresolved targets remain external evidence.
Rehabilitation following surgery for flexor tendon injuries of the hand
2021 · External reference
Flexor tendon repair
10.1002/jor.1100040116 · 1986 · External reference
Tendon healing: repair and regeneration
10.1146/annurev-bioeng-071811-150122 · 2012 · External reference
Flexor Tendon: development, healing, adhesion formation, and contributing growth factors
10.1097/prs.0000000000006048 · 2019 · External reference
Prevention of adhesions in surgery of the flexor tendons of the hand: what is the evidence?
10.1093/bmb/ldp013 · 2009 · External reference
Flexor Tendon adhesion formation: current concepts
10.1016/j.hcl.2022.08.018 · 2023 · External reference
10.1016/j.actbio.2021.01.027
10.1016/j.actbio.2021.01.027 · External reference
Clinical outcomes associated with flexor tendon repair
10.1016/j.hcl.2004.11.005 · 2005 · External reference
The cellular basis of fibrotic tendon healing: challenges and opportunities
10.1016/j.trsl.2019.02.002 · 2019 · External reference
The incidence of acute traumatic tendon injuries in the hand and wrist: a 10-year population-based study
10.4055/cios.2014.6.2.196 · 2014 · External reference
10.1016/j.matbio.2019.07.008
10.1016/j.matbio.2019.07.008 · External reference
Phalangeal fractures requiring vascular reconstruction: epidemiology and factors predictive of reoperation
2022 · External reference
Microsurgical principles and postoperative adhesions: lessons from the past
10.1016/j.fertnstert.2016.08.040 · 2016 · External reference
Research on mechanisms of chinese medicines in prevention and treatment of postoperative adhesion
10.1007/s11655-023-3735-0 · 2023 · External reference
New adhesion formation after laparoscopic and conventional adhesiolysis: a comparative study in the rabbit
10.1007/s004640000256 · 2001 · External reference
Research on mechanisms of chinese medicines in prevention and treatment of postoperative adhesion
2023 · External reference
Reduction of postoperative adhesion development
10.1016/j.fertnstert.2016.08.029 · 2016 · External reference
A review of physiological and cellular mechanisms underlying fibrotic postoperative adhesion
10.7150/ijbs.54403 · 2021 · External reference
Drug-incorporated electrospun fibers efficiently prevent postoperative adhesion
10.2174/1381612821666150302152420 · 2015 · External reference
Basic research on Tendon repair: strategies, evaluation, and development
2021 · External reference
Tendon tissue repair in prospective of drug delivery, regenerative medicines, and innovative bioscaffolds
10.1155/2021/1488829 · 2021 · External reference
Electrospun nanofibrous membranes for preventing tendon adhesion
10.1021/acsbiomaterials.0c00201 · 2020 · External reference
The growth factors involved in flexor tendon repair and adhesion formation
10.1177/1753193413509231 · 2014 · External reference
The role of the macrophage in tendinopathy and tendon healing
10.1002/jor.24667 · 2020 · External reference
LncRNA XIST prevents tendon adhesion and promotes tendon repair through the miR-26a-5p/COX2 Pathway
10.1007/s12033-021-00419-3 · 2022 · External reference
A natural hydrogel with prohealing properties enhances tendon regeneration
2022 · External reference
In-situ growth of robust superlubricated nano-skin on electrospun nanofibers for post-operative adhesion prevention
2022 · External reference
The past, present and future in scaffold-based tendon treatments
10.1016/j.addr.2014.11.022 · 2015 · External reference
10.1016/j.actbio.2017.08.032
10.1016/j.actbio.2017.08.032 · External reference
The tendon microenvironment: engineered in vitro models to study cellular crosstalk
10.1016/j.addr.2022.114299 · 2022 · External reference
Advances in biomaterials for preventing tissue adhesion
10.1016/j.jconrel.2017.06.020 · 2017 · External reference
Tendon vasculature in health and disease
10.3389/fphys.2015.00330 · 2015 · External reference
Pathogenesis of postoperative adhesion formation
10.1002/bjs.7657 · 2011 · External reference
10.1080/03008207.2018.1512979
10.1080/03008207.2018.1512979 · External reference
Biological amnion prevents flexor tendon adhesion in zone II: a controlled, multicentre clinical trial
2019 · External reference
Molecular biology of flexor tendon healing in relation to reduction of tendon adhesions
10.1016/j.jhsa.2017.06.013 · 2017 · External reference
Dynamic exacerbation in inflammation and oxidative stress during the formation of peritendinous adhesion resulted from acute tendon injury
2021 · External reference
RelA/p65 inhibition prevents tendon adhesion by modulating inflammation, cell proliferation, and apoptosis
10.1038/cddis.2017.135 · 2017 · External reference
Gene Silencing via PDA/ERK2-siRNA-mediated electrospun fibers for peritendinous antiadhesion
2019 · External reference
Neutralization of excessive levels of active TGF-beta1 reduces MSC recruitment and differentiation to mitigate peritendinous adhesion.
2023 · External reference
10.1016/j.imbio.2013.09.001
10.1016/j.imbio.2013.09.001 · External reference
Changes in macrophage phenotype and induction of epithelial-to-mesenchymal transition genes following acute Achilles tenotomy and repair
10.1002/jor.22624 · 2014 · External reference
10.1016/j.actbio.2022.10.004
10.1016/j.actbio.2022.10.004 · External reference
Macrophage polarization modulated by NF-kappaB in polylactide membranes-treated peritendinous adhesion.
10.1002/smll.202104112 · 2022 · External reference
Surface modification of electrospun fibers with mechano-growth factor for mitigating the foreign-body reaction
2021 · External reference
10.1016/j.omtn.2018.11.006
10.1016/j.omtn.2018.11.006 · External reference
Cox-2 inhibition and the composition of inflammatory cell populations during early and mid-time tendon healing
10.11138/mltj/2017.7.2.223 · 2017 · External reference
High concentration of aspirin induces apoptosis in rat tendon stem cells via inhibition of the Wnt/beta-catenin pathway.
10.1159/000495050 · 2018 · External reference
Deletion of EP4 in S100a4-lineage cells reduces scar tissue formation during early but not later stages of tendon healing
10.1038/s41598-017-09407-7 · 2017 · External reference
Systemic EP4 inhibition increases adhesion formation in a murine model of flexor tendon repair
10.1371/journal.pone.0136351 · 2015 · External reference
10.1177/1933719114522550
10.1177/1933719114522550 · External reference
Local vitamin-C injection reduced tendon adhesion in a chicken model of flexor digitorum profundus tendon injury
2013 · External reference
Hydrogen treatment reduces tendon adhesion and inflammatory response
10.1002/jcb.27441 · 2019 · External reference
Roles of oxidative stress in acute tendon injury and degenerative tendinopathy-A target for intervention
2022 · External reference
Reevaluation of pluripotent cytokine TGF-beta3 in immunity.
10.3390/ijms19082261 · 2018 · External reference
Tgfbeta signaling is required for tenocyte recruitment and functional neonatal tendon regeneration.
2020 · External reference
HGF inhibits TGF-beta1-induced myofibroblast differentiation and ECM deposition via MMP-2 in Achilles tendon in rat.
10.1007/s00421-010-1764-4 · 2011 · External reference
Rebalancing SMAD7/SMAD3 signaling reduces adhesion formation during flexor tendon healing
10.4014/jmb.2209.09033 · 2023 · External reference
TGF-beta in developmental and fibrogenic EMTs.
10.1016/j.semcancer.2022.09.004 · 2022 · External reference
10.1016/j.tibs.2015.03.012
10.1016/j.tibs.2015.03.012 · External reference
10.1038/cr.2008.328
10.1038/cr.2008.328 · External reference
TGF-beta3 regulates adhesion formation through the JNK/c-Jun pathway during flexor tendon healing
10.1186/s12891-021-04691-x · 2021 · External reference
Nanoparticle-mediated delivery of TGF-beta1 miRNA plasmid for preventing flexor tendon adhesion formation
10.1016/j.biomaterials.2013.07.072 · 2013 · External reference
TGF-beta1 reverses the effects of matrix anchorage on the gene expression of decorin and procollagen type I in tendon fibroblasts
10.1097/01.blo.0000145887.48534.6f · 2005 · External reference
PXL01 in sodium hyaluronate for improvement of hand recovery after flexor tendon repair surgery: randomized controlled trial
2014 · External reference
Injectable collagenase clostridium histolyticum for Dupuytren's contracture
10.1056/nejmoa0810866 · 2009 · External reference
Effect of Heparin on post-operative adhesion in flexor tendon surgery of the hand
10.1007/s12593-015-0192-4 · 2015 · External reference
Effects of nonsteroidal anti-inflammatory drugs on flexor tendon adhesion
10.1016/j.jhsa.2010.02.033 · 2010 · External reference
Ibuprofen-loaded hyaluronic acid nanofibrous membranes for prevention of postoperative tendon adhesion through reduction of inflammation
2019 · External reference
Controlled release of curcumin from curcumin-loaded nanomicelles to prevent peritendinous adhesion during Achilles tendon healing in rats
2016 · External reference
10.1016/j.jconrel.2021.04.017
10.1016/j.jconrel.2021.04.017 · External reference
Effect of angiotensin II pathway inhibitors on post-surgical adhesion band formation: a potential repurposing of old drugs
10.1016/j.injury.2022.08.046 · 2022 · External reference
Local administration of Trolox, a vitamin E analog, reduced tendon adhesion in a chicken model of flexor digitorum profundus tendon injury
2017 · External reference
Down-regulating ERK1/2 and SMAD2/3 phosphorylation by physical barrier of celecoxib-loaded electrospun fibrous membranes prevents tendon adhesions
10.1016/j.biomaterials.2014.08.028 · 2014 · External reference
The use of tamoxifenin prevention of adhesions after flexor tendons surgery in rabbits
2019 · External reference
Tamoxifen prevents peritendinous adhesions: a preliminary report
10.1155/2022/4250771 · 2022 · External reference
Rapamycin protects against peritendinous fibrosis through activation of autophagy
10.3389/fphar.2018.00402 · 2018 · External reference
10.1002/iub.2013
10.1002/iub.2013 · External reference
Hydroxycamptothecin inhibits peritendinous adhesion via the endoplasmic reticulum stress-dependent apoptosis
2019 · External reference
Gene therapy strategies to improve strength and quality of flexor tendon healing
10.1517/14712598.2016.1134479 · 2016 · External reference
10.3390/ijms14024361
10.3390/ijms14024361 · External reference
MMP-2 responsive unidirectional hydrogel-electrospun patch loading TGF-beta 1 siRNA polyplexes for peritendinous anti-adhesion
2021 · External reference
Adeno-associated virus-2-mediated bFGF gene transfer to digital flexor tendons significantly increases healing strength. an in vivo study
10.2106/jbjs.f.01188 · 2008 · External reference
10.1016/j.actbio.2021.01.008
10.1016/j.actbio.2021.01.008 · External reference
Hyaluronic acid treatment improves healing of the tenorrhaphy site by suppressing adhesions through extracellular matrix remodeling in a rat model
2021 · External reference
Reduction of tendon adhesions following administration of Adaprev, a hypertonic solution of mannose-6-phosphate: mechanism of action studies
2014 · External reference
Efficacy of hyaluronic acid/nonsteroidal anti-inflammatory drug systems in preventing postsurgical tendon adhesions
10.1002/(sici)1097-4636(199721)38:1<25::aid-jbm4>3.0.co;2-j · 1997 · External reference
Preparation and characterization of antiadhesion barrier film from hyaluronic acid-grafted electrospun poly(caprolactone) nanofibrous membranes for prevention of flexor tendon postoperative peritendinous adhesion
10.2147/ijn.s67931 · 2014 · External reference
Dual functional core-sheath electrospun hyaluronic acid/polycaprolactone nanofibrous membranes embedded with silver nanoparticles for prevention of peritendinous adhesion
10.1016/j.actbio.2015.07.041 · 2015 · External reference
Thermo-responsive in-situ forming hydrogels as barriers to prevent post-operative peritendinous adhesion
10.1016/j.actbio.2017.09.010 · 2017 · External reference
M2 macrophage membrane-mediated biomimetic-nanoparticle carrying COX-siRNA targeted delivery for prevention of tendon adhesions by inhibiting inflammation
2023 · External reference
Novel enzyme-sensitive poly-tioxolone membranes for peritendinous anti-adhesion
2022 · External reference
Effects of laser versus scalpel tenolysis in the rabbit flexor tendon
10.1097/00006534-199603000-00016 · 1996 · External reference
Adhesions from flexor tendon surgery: an animal study comparing surgical techniques
10.1053/jhsu.2000.jhsu25a0252 · 2000 · External reference
Effectiveness of high-intensity laser therapy plus ultrasound-guided peritendinous hyaluronic acid compared to therapeutic exercise for patients with lateral elbow tendinopathy
10.3390/jcm11195492 · 2022 · External reference
Ultrasound therapy in tendinous injury healing in goats
10.1111/j.1439-0442.2006.00816.x · 2006 · External reference
Ultrasound therapy during experimental tendinous injury healing in rabbits
2008 · External reference
Comparison of the effects of pulsed electromagnetic field and extracorporeal shockwave therapy in a rabbit model of experimentally induced achilles tendon injury
10.1002/bem.22314 · 2021 · External reference
10.3389/fvets.2022.851894
10.3389/fvets.2022.851894 · External reference
Effectiveness of combined extracorporeal shock-wave therapy and hyaluronic acid injections for patients with shoulder pain due to rotator cuff tendinopathy: a person-centered approach with a focus on gender differences to treatment response
10.1186/s12891-022-05819-3 · 2022 · External reference
A phlorotannins-loaded homogeneous acellular matrix film modulates post-implantation inflammatory responses
10.1002/term.3258 · 2022 · External reference
Macrophage infiltration of electrospun polyester fibers
10.1039/c6bm00958a · 2017 · External reference
Effect of mitomycin-C on post-operative adhesions in tendon surgery: an experimental study in rats
10.1302/0301-620x.92b6.23534 · 2010 · External reference
Sustained release of dicumarol via novel grafted polymer in electrospun nanofiber membrane for treatment of peritendinous adhesion
2023 · External reference
Combined verapamil-polydopamine nanoformulation inhibits adhesion formation in achilles tendon injury using rat model
10.2147/ijn.s377600 · 2023 · External reference
Improved tendon healing by a combination of Tanshinone IIA and miR-29b inhibitor treatment through preventing tendon adhesion and enhancing tendon strength
10.7150/ijms.44138 · 2020 · External reference
MicroRNA-21-3p engineered umbilical cord stem cell-derived exosomes inhibit tendon adhesion
10.2147/jir.s254879 · 2020 · External reference
Upregulation of HSP72 attenuates tendon adhesion by regulating fibroblast proliferation and collagen production via blockade of the STAT3 signaling pathway
2020 · External reference
Hyaluronic acid/platelet rich plasma-infused core-shell nanofiber membrane to prevent postoperative tendon adhesion and promote tendon healing
2023 · External reference
Follistatin mitigates myofibroblast differentiation and collagen synthesis of fibroblasts from scar tissue around injured flexor tendons
10.3349/ymj.2020.61.1.85 · 2020 · External reference
Prevention of peritendinous adhesion formation after the flexor tendon surgery in rabbits: a comparative study between use of local interferon-alpha, interferon-beta, and 5-fluorouracil
10.1097/sap.0000000000001169 · 2018 · External reference
Metformin prevents peritendinous fibrosis by inhibiting transforming growth factor-beta signaling
10.18632/oncotarget.21695 · 2017 · External reference
Tendon healing in vivo: effect of mannose-6-phosphate on flexor tendon adhesion formation
2012 · External reference
Chitosan inhibits fibroblasts growth in Achilles tendon via TGF-beta1/Smad3 pathway by miR-29b
2014 · External reference
Effects of chitosan on cell proliferation and collagen production of tendon sheath fibroblasts, epitenon tenocytes, and endotenon tenocytes
2005 · External reference
A collagen prolyl 4-hydroxylase inhibitor reduces adhesions after tendon injury
10.1097/01.blo.0000229281.60732.f8 · 2006 · External reference
Sustained-release hydrogel-based rhynchophylline delivery system improved injured tendon repair
2021 · External reference
Experimental study on basic fibroblast growth factor combined slow-releasing degradable membrane to prevent tendon adhesion
2004 · External reference
