Research graph
References from A shared mechanism for TNP-ATP recognition by members of the P2X receptor family. Local targets link to admitted publications; unresolved targets remain external evidence.
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A new class of ligand- gated ion channel defined by P2X receptor for extracellular ATP
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Lipids regulate P2X7- receptor-dependent actin assembly by phagosomes via ADP translocation and ATP synthesis in the phagosome lumen
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ATP-gated P2X receptors in health and disease
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Keratinocytes mediate innocuous and noxious touch via ATP-P2X4 signaling
2018 · External reference
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Medicinal chemistry of P2X receptors: allosteric modulators
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BLU-5937: a selective P2X3 antagonist with potent anti- tussive effect and no taste alteration
10.1016/j.pupt.2019.03.007 · 2019 · External reference
Fluorescence imaging of extracellular purinergic receptor sites and putative ecto-ATPase sites on isolated cochlear hair cells
10.1523/jneurosci.14-11-06992.1994 · 1994 · External reference
Competitive antagonism of recombinant P2X(2/3) receptors by 2', 3'-O-(2,4,6-trinitrophenyl) adenosine 5'-triphosphate (TNP-ATP)
2000 · External reference
2′,3′-O-(2,4,6- trinitrophenyl) adenosine 5′- triphosphate (TNP-ATP)–a nanomolar affinity antagonist at rat mesenteric artery P2X receptor ion channels
10.1038/sj.bjp.0702001 · 2009 · External reference
10.1016/s0026-895x(24)13265-8
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2',3'-O- Substituted ATP derivatives as potent antagonists of purinergic P2X3 receptors and potential analgesic agents
10.1007/s11302-016-9539-y · 2017 · External reference
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Molecular mechanism of ATP binding and ion channel activation in P2X receptors
10.1038/nature11010 · 2012 · External reference
Structural basis for subtype-specific inhibition of the P2X7 receptor
2016 · External reference
Structural insights into divalent cation modulations of ATP-gated P2X receptor channels
10.1016/j.celrep.2015.12.087 · 2016 · External reference
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Involvement of the cysteine-rich head domain in activation and desensitization of the P2X1 receptor
10.1073/pnas.1118759109 · 2012 · External reference
Druggable negative allosteric site of P2X3 receptors
10.1073/pnas.1800907115 · 2018 · External reference
Structural insights into the competitive inhibition of the ATP-gated P2X receptor channel
10.1038/s41467-017-00887-9 · 2017 · External reference
Conductance of P2X4 purinergic receptor is determined by conformational equilibrium in the transmembrane region
10.1073/pnas.1600519113 · 2016 · External reference
10.1038/nature08198
10.1038/nature08198 · External reference
Molecular mechanism underlying the subtype-selectivity of competitive inhibitor NF110 and its distinct potencies in human and rat P2X3 receptors
10.1016/j.scib.2018.11.016 · 2018 · External reference
Intersubunit physical couplings fostered by the left flipper domain facilitate channel opening of P2X4 receptors
10.1074/jbc.m116.771121 · 2017 · External reference
Vanilloid agonist-mediated activation of TRPV1 channels requires coordinated movement of the S1-S4 bundle rather than a quiescent state
10.1016/j.scib.2022.02.016 · 2022 · External reference
Dynamic recognition of naloxone, morphine and endomorphin1 in the same pocket of micro-opioid receptors
2022 · External reference
10.1016/j.csbj.2022.03.030
10.1016/j.csbj.2022.03.030 · External reference
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OPM database and PPM web server: resources for positioning of proteins in membranes
10.1093/nar/gkr703 · 2012 · External reference
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10.1021/ja9621760 · External reference
10.1002/jcc.20292
10.1002/jcc.20292 · External reference
Role of the ectodomain serine 275 in shaping the binding pocket of the ATP-gated P2X3 receptor
10.1021/bi200812u · 2011 · External reference
Agonist antagonist interactions at the rapidly desensitizing P2X3 receptor
10.1371/journal.pone.0079213 · 2013 · External reference
10.1103/physrevlett.100.020603
10.1103/physrevlett.100.020603 · External reference
