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References from DataXflow: Synergizing data-driven modeling with best parameter fit and optimal control – An efficient data analysis for cancer research. Local targets link to admitted publications; unresolved targets remain external evidence.
Single-cell transcriptomics: current methods and challenges in data acquisition and analysis
10.3389/fnins.2021.591122 · 2021 · External reference
10.1038/nrc4029
10.1038/nrc4029 · External reference
10.1016/j.cell.2006.09.042
10.1016/j.cell.2006.09.042 · External reference
A mathematical model describes the malignant transformation of low grade gliomas: Prognostic implications
10.1371/journal.pone.0179999 · 2017 · External reference
On the SQH Scheme to Solve Nonsmooth PDE Optimal Control Problems
10.1080/01630563.2019.1599911 · 2019 · External reference
How to Steer and Control ERK and the ERK Signaling Cascade Exemplified by Looking at Cardiac Insufficiency
10.3390/ijms20092179 · 2019 · External reference
An effective model of endogenous clocks and external stimuli determining circadian rhythms
10.1038/s41598-021-95391-y · 2021 · External reference
Analyzing pharmacological intervention points: A method to calculate external stimuli to switch between steady states in regulatory networks
10.1371/journal.pcbi.1007075 · 2019 · External reference
A modular systems biological modelling framework studies cyclic nucleotide signaling in platelets
10.1016/j.jtbi.2022.111222 · 2022 · External reference
Data driven model discovery and interpretation for CAR T-cell killing using sparse identification and latent variables
10.3389/fimmu.2023.1115536 · 2023 · External reference
10.1016/j.csbj.2023.06.002 · Admitted local publication
Mathematical Modeling Identifies Optimum Palbociclib-fulvestrant Dose Administration Schedules for the Treatment of Patients with Estrogen Receptor-positive Breast Cancer
10.1158/2767-9764.crc-23-0257 · 2023 · External reference
10.1126/scitranslmed.3002356
10.1126/scitranslmed.3002356 · External reference
E-cadherin deregulation in breast cancer
10.1111/jcmm.15140 · 2020 · External reference
10.1186/s12943-020-01305-3
10.1186/s12943-020-01305-3 · External reference
10.1371/journal.pone.0013283
10.1371/journal.pone.0013283 · External reference
Robust and efficient parameter estimation in dynamic models of biological systems
10.1186/s12918-015-0219-2 · 2015 · External reference
Optimal radiation fractionation for low-grade gliomas: Insights from a mathematical model
10.1016/j.mbs.2015.05.006 · 2015 · External reference
Modeling and numerical solution of a cancer therapy optimal control problem
2018 · External reference
CD44: a multifunctional mediator of cancer progression
10.3390/biom11121850 · 2021 · External reference
COPASI--a COmplex PAthway SImulator
10.1093/bioinformatics/btl485 · 2006 · External reference
10.1016/j.cell.2018.01.006
10.1016/j.cell.2018.01.006 · External reference
FBXW7 tumor suppressor regulation by dualspecificity tyrosine-regulated kinase 2
10.1038/s41419-023-05724-0 · 2023 · External reference
Software JimenaE allows efficient dynamic simulations of Boolean networks, centrality and system state analysis
10.1038/s41598-022-27098-7 · 2023 · External reference
GSK3 suppression upregulates beta-catenin and c-Myc to abrogate KRas-dependent tumors
10.1038/s41467-018-07644-6 · 2018 · External reference
10.1634/theoncologist.2019-0846
10.1634/theoncologist.2019-0846 · External reference
10.1371/journal.pcbi.1000696
10.1371/journal.pcbi.1000696 · External reference
10.1038/s41417-021-00383-9
10.1038/s41417-021-00383-9 · External reference
Unresolved reference
External reference
10.1016/j.tranon.2018.03.009
10.1016/j.tranon.2018.03.009 · External reference
A method for the generation of standardized qualitative dynamical systems of regulatory networks
10.1186/1742-4682-3-13 · 2006 · External reference
10.1007/s11538-011-9711-z
10.1007/s11538-011-9711-z · External reference
miR-183-5p functions as a tumor suppressor in lung cancer through PIK3CA inhibition
10.1016/j.yexcr.2018.12.003 · 2019 · External reference
A mathematical model for predicting the spatiotemporal response of breast cancer cells treated with doxorubicin
10.1080/15384047.2024.2321769 · 2024 · External reference
10.1007/s10911-011-9216-2
10.1007/s10911-011-9216-2 · External reference
10.1158/1078-0432.ccr-16-2811
10.1158/1078-0432.ccr-16-2811 · External reference
10.1038/s41586-019-1526-3
10.1038/s41586-019-1526-3 · External reference
Targeting NFE2L2/KEAP1 Mutations in Advanced NSCLC With the TORC1/2 Inhibitor TAK-228
10.1016/j.jtho.2022.09.225 · 2023 · External reference
10.1016/j.ejmech.2024.116194
10.1016/j.ejmech.2024.116194 · External reference
EMT, stemness, and drug resistance in biological context: a 3D tumor tissue/in silico platform for analysis of combinatorial treatment in NSCLC with aggressive KRAS-biomarker signatures
10.3390/cancers14092176 · 2022 · External reference
Delay effects in the response of low-grade gliomas to radiotherapy: a mathematical model and its therapeutical implications
10.1093/imammb/dqu009 · 2015 · External reference
Computational design of improved standardized chemotherapy protocols for grade II oligodendrogliomas
10.1371/journal.pcbi.1006778 · 2019 · External reference
10.1371/journal.pone.0231137
10.1371/journal.pone.0231137 · External reference
XP-524 is a dual-BET/EP300 inhibitor that represses oncogenic KRAS and potentiates immune checkpoint inhibition in pancreatic cancer
2022 · External reference
10.1371/journal.pone.0302045 · 2024 · Admitted local publication
10.1371/journal.pone.0074335
10.1371/journal.pone.0074335 · External reference
10.1093/bioinformatics/btv405
10.1093/bioinformatics/btv405 · External reference
Hybrid models of tumor growth
10.1002/wsbm.102 · 2011 · External reference
10.1186/s12885-020-07573-y
10.1186/s12885-020-07573-y · External reference
Role of NRF2 in Lung Cancer
10.3390/cells10081879 · 2021 · External reference
10.1093/bioinformatics/btz581
10.1093/bioinformatics/btz581 · External reference
10.1615/critreveukaryotgeneexpr.2023046830
10.1615/critreveukaryotgeneexpr.2023046830 · External reference
Elliptic optimal control problems with L 1-control cost and applications for the placement of control devices
10.1007/s10589-007-9150-9 · 2007 · External reference
PESTO: Parameter EStimation TOolbox
10.1093/bioinformatics/btx676 · 2018 · External reference
10.1158/0008-5472.can-11-1399
10.1158/0008-5472.can-11-1399 · External reference
Genetic and epigenetic alterations of CDH1 regulatory regions in hereditary and sporadic gastric cancer
10.3390/ph14050457 · 2021 · External reference
Immunoproteasome deficiency is a feature of non-small cell lung cancer with a mesenchymal phenotype and is associated with a poor outcome
2016 · External reference
10.1137/15m1044825
10.1137/15m1044825 · External reference
10.1158/0008-5472.can-19-2669
10.1158/0008-5472.can-19-2669 · External reference
Non-small cell lung cancer targeted therapy: drugs and mechanisms of drug resistance
2022 · External reference
10.1016/j.compbiomed.2022.105697
10.1016/j.compbiomed.2022.105697 · External reference
10.1038/s41586-019-1884-x
10.1038/s41586-019-1884-x · External reference
10.1002/med.21399
10.1002/med.21399 · External reference
Cdh1 functions as an oncogene by inducing self-renewal of lung cancer stem-like cells via oncogenic pathways
10.7150/ijbs.38672 · 2020 · External reference
Loss of TP53 cooperates with c-MET overexpression to drive hepatocarcinogenesis
10.1038/s41419-023-05958-y · 2023 · External reference