Research graph
References from Integration of single-nucleus and exosome RNA sequencing dissected inter-cellular communication and biomarkers in pancreatic ductal adenocarcinoma. Local targets link to admitted publications; unresolved targets remain external evidence.
Understanding cell-cell communication and signaling in the colorectal cancer microenvironment
10.1002/ctm2.308 · 2021 · External reference
Mapping and validation of scRNA-seq-derived cell-cell communication networks in the tumor microenvironment
10.3389/fimmu.2022.885267 · 2022 · External reference
Hepatitis B virus P protein initiates glycolytic bypass in HBV-related hepatocellular carcinoma via a FOXO3/miRNA-30b-5p/MINPP1 axis
10.1186/s13046-020-01803-8 · 2021 · External reference
FOXO3A-induced LINC00926 suppresses breast tumor growth and metastasis through inhibition of PGK1-mediated Warburg effect
10.1016/j.ymthe.2021.04.036 · 2021 · External reference
Pan-tumor genomic biomarkers for PD-1 checkpoint blockade-based immunotherapy
10.1126/science.aar3593 · 2018 · External reference
10.1038/s41587-020-0465-8
10.1038/s41587-020-0465-8 · External reference
FOXO3a‑SIRT6 axis suppresses aerobic glycolysis in melanoma
2020 · External reference
10.1038/s41596-020-0379-4
10.1038/s41596-020-0379-4 · External reference
MicroRNA sequence codes for small extracellular vesicle release and cellular retention
10.1038/s41586-021-04234-3 · 2022 · External reference
Inference and analysis of cell-cell communication using CellChat
10.1038/s41467-021-21246-9 · 2021 · External reference
Downregulated miRNA-26a-5p induces the apoptosis of endothelial cells in coronary heart disease by inhibiting PI3K/AKT pathway
2019 · External reference
10.1126/science.aau6977
10.1126/science.aau6977 · External reference
10.1016/j.cell.2021.07.020
10.1016/j.cell.2021.07.020 · External reference
10.1016/j.celrep.2018.10.047
10.1016/j.celrep.2018.10.047 · External reference
10.1146/annurev.pathol.4.110807.092222
10.1146/annurev.pathol.4.110807.092222 · External reference
Applications of single-cell sequencing in cancer research: progress and perspectives
10.1186/s13045-021-01105-2 · 2021 · External reference
Six MicroRNA prognostic models for overall survival of lung adenocarcinoma
2022 · External reference
Localisation of PGK1 determines metabolic phenotype to balance metastasis and proliferation in patients with SMAD4-negative pancreatic cancer
10.1136/gutjnl-2018-317163 · 2020 · External reference
CRIP1 fosters MDSC trafficking and resets tumour microenvironment via facilitating NF-κB/p65 nuclear translocation in pancreatic ductal adenocarcinoma
2023 · External reference
miR-1293 suppresses tumor malignancy by targeting hydrocyanic oxidase 2: therapeutic potential of a miR-1293/Hydrocyanic oxidase 2 axis in renal cell carcinoma
10.1089/cbr.2019.2957 · 2020 · External reference
Impact of miRNA in atherosclerosis
2018 · External reference
hsa-mir-3199-2 and hsa-mir-1293 as Novel Prognostic Biomarkers of Papillary Renal Cell Carcinoma by COX Ratio Risk Regression Model Screening
10.1002/jcb.26008 · 2017 · External reference
Crosstalk between cancer-associated fibroblasts and immune cells in the tumor microenvironment: new findings and future perspectives
10.1186/s12943-021-01428-1 · 2021 · External reference
Exosomes: composition, biogenesis, and mechanisms in cancer metastasis and drug resistance
10.1186/s12943-019-0991-5 · 2019 · External reference
10.1172/jci123106
10.1172/jci123106 · External reference
10.1016/j.semcancer.2019.07.024
10.1016/j.semcancer.2019.07.024 · External reference
Pancreatic cancer-secreted miR-155 implicates in the conversion from normal fibroblasts to cancer-associated fibroblasts
10.1111/cas.12747 · 2015 · External reference
Cancer-associated fibroblasts suppress ferroptosis and induce gemcitabine resistance in pancreatic cancer cells by secreting exosome-derived ACSL4-targeting miRNAs
2023 · External reference
PD-L1, TMB, MSI, and other predictors of response to immune checkpoint inhibitors in biliary tract cancer
10.3390/cancers13030558 · 2021 · External reference
Circular RNA CircEYA3 induces energy production to promote pancreatic ductal adenocarcinoma progression through the miR-1294/c-Myc axis
10.1186/s12943-021-01400-z · 2021 · External reference
10.1038/nrd.2016.246
10.1038/nrd.2016.246 · External reference
Targeting LIF-mediated paracrine interaction for pancreatic cancer therapy and monitoring
10.1038/s41586-019-1130-6 · 2019 · External reference
The PI3K-AKT-mTOR pathway and prostate cancer: at the crossroads of AR, MAPK, and WNT Signaling
10.3390/ijms21124507 · 2020 · External reference
Cancer Statistics, 2021
2021 · External reference
Growth Factors, PI3K/AKT/mTOR and MAPK Signaling Pathways in Colorectal Cancer Pathogenesis: Where Are We Now?
10.3390/ijms221910260 · 2021 · External reference
Identification of cell cycle as the critical pathway modulated by exosome-derived microRNAs in gallbladder carcinoma
10.1007/s12032-021-01594-8 · 2021 · External reference
Data analysis guidelines for single-cell RNA-seq in biomedical studies and clinical applications
2022 · External reference
Identification of the Roles of a Stemness Index Based on mRNA expression in the prognosis and metabolic reprograming of pancreatic ductal adenocarcinoma
2021 · External reference
Targeting neoadjuvant chemotherapy-induced metabolic reprogramming in pancreatic cancer promotes anti-tumor immunity and chemo-response
2023 · External reference
10.1158/0008-5472.can-17-3841
10.1158/0008-5472.can-17-3841 · External reference
10.1038/s41568-021-00427-0
10.1038/s41568-021-00427-0 · External reference
miRNA-17-92 protects endothelial cells from erastin-induced ferroptosis through targeting the A20-ACSL4 axis
10.1016/j.bbrc.2019.05.147 · 2019 · External reference
Serum exosomal miR-638 is a prognostic marker of HCC via downregulation of VE-cadherin and ZO-1 of endothelial cells
10.1111/cas.14807 · 2021 · External reference
METTL14 regulates M6A methylation-modified primary miR-19a to promote cardiovascular endothelial cell proliferation and invasion
2020 · External reference
CAF secreted miR-522 suppresses ferroptosis and promotes acquired chemo-resistance in gastric cancer
10.1186/s12943-020-01168-8 · 2020 · External reference
Immunomodulatory Properties of PI3K/AKT/mTOR and MAPK/MEK/ERK inhibition augment response to immune checkpoint blockade in melanoma and triple-negative breast cancer
2022 · External reference
MiR-223-3p targets FOXO3a to inhibit radiosensitivity in prostate cancer by activating glycolysis
10.1016/j.lfs.2021.119798 · 2021 · External reference
Bioinformatics analysis of tumor-educated platelet microRNAs in patients with hepatocellular carcinoma
2021 · External reference
