Research graph
References from Rational design of monomeric IL37 variants guided by stability and dynamical analyses of IL37 dimers. Local targets link to admitted publications; unresolved targets remain external evidence.
10.1111/imr.12621
10.1111/imr.12621 · External reference
Il-38 binds to the il-36 receptor and has biological effects on immune cells similar to il-36 receptor antagonist
10.1073/pnas.1121534109 · 2012 · External reference
Brief report: interleukin-38 exerts antiinflammatory functions and is associated with disease activity in systemic lupus erythematosus
10.1002/art.39328 · 2015 · External reference
Il-1 family nomenclature
10.1038/ni1110-973 · 2010 · External reference
10.1073/pnas.1819672116
10.1073/pnas.1819672116 · External reference
Homodimerization attenuates the anti-inflammatory activity of interleukin-37
2017 · External reference
Biology of interleukin-37 and its role in autoimmune diseases
2022 · External reference
10.1016/j.chembiol.2021.10.004
10.1016/j.chembiol.2021.10.004 · External reference
Il-37 exerts therapeutic effects in experimental autoimmune encephalomyelitis through the receptor complex il-1r5/il-1r8
10.7150/thno.47435 · 2021 · External reference
10.1007/s13238-017-0408-4
10.1007/s13238-017-0408-4 · External reference
10.1021/acs.jcim.2c00054
10.1021/acs.jcim.2c00054 · External reference
10.1093/bioinformatics/btn268
10.1093/bioinformatics/btn268 · External reference
10.1126/science.2471267
10.1126/science.2471267 · External reference
10.1534/genetics.117.300064
10.1534/genetics.117.300064 · External reference
10.1016/j.csbj.2023.06.021 · Admitted local publication
Comparative protein modelling by satisfaction of spatial restraints
10.1006/jmbi.1993.1626 · 1993 · External reference
10.1110/ps.062416606
10.1110/ps.062416606 · External reference
10.1126/science.abj8754
10.1126/science.abj8754 · External reference
Protein complex prediction with alphafold-multimer
2021 · External reference
10.1038/s41586-021-03819-2
10.1038/s41586-021-03819-2 · External reference
10.1038/s41592-022-01488-1
10.1038/s41592-022-01488-1 · External reference
Mmseqs2 desktop and local web server app for fast, interactive sequence searches
10.1093/bioinformatics/bty1057 · 2019 · External reference
10.1038/nbt.3988
10.1038/nbt.3988 · External reference
Benchmarking alphafold for protein complex modeling reveals accuracy determinants
2022 · External reference
Alphafold2 and its applications in the fields of biology and medicine
10.1038/s41392-023-01381-z · 2023 · External reference
lddt: a local superposition-free score for comparing protein structures and models using distance difference tests
10.1093/bioinformatics/btt473 · 2013 · External reference
10.1002/jcc.20945
10.1002/jcc.20945 · External reference
10.1002/jcc.21287
10.1002/jcc.21287 · External reference
Charmm-gui input generator for namd, gromacs, amber, openmm, and charmm/openmm simulations using the charmm36 additive force field
2016 · External reference
Pdb2pqr: an automated pipeline for the setup of Poisson–Boltzmann electrostatics calculations
10.1093/nar/gkh381 · 2004 · External reference
10.1002/pro.3280
10.1002/pro.3280 · External reference
10.1002/jcc.20289
10.1002/jcc.20289 · External reference
All-atom empirical potential for molecular modeling and dynamics studies of proteins
10.1021/jp973084f · 1998 · External reference
Charmm36 all-atom additive protein force field: validation based on comparison to nmr data
10.1002/jcc.23354 · 2013 · External reference
10.1063/1.445869
10.1063/1.445869 · External reference
10.1063/1.464397
10.1063/1.464397 · External reference
Constant pressure molecular dynamics algorithms
10.1063/1.467468 · 1994 · External reference
Constant pressure molecular dynamics simulation: the Langevin piston method
10.1063/1.470648 · 1995 · External reference
An analysis of the accuracy of Langevin and molecular dynamics algorithms
10.1080/00268978800101881 · 1988 · External reference
10.25080/majora-629e541a-00e
10.25080/majora-629e541a-00e · External reference
Mdanalysis: a toolkit for the analysis of molecular dynamics simulations
10.1002/jcc.21787 · 2011 · External reference
Vmd: visual molecular dynamics
10.1016/0263-7855(96)00018-5 · 1996 · External reference
10.1002/pro.3943
10.1002/pro.3943 · External reference
10.1002/pro.3235
10.1002/pro.3235 · External reference
Ucsf chimerax: tools for structure building and analysis
2023 · External reference
The bio3d packages for structural bioinformatics
10.1002/pro.3923 · 2021 · External reference
The foldx web server: an online force field
10.1093/nar/gki387 · 2005 · External reference
Mmpbsa. py: an efficient program for end-state free energy calculations
10.1021/ct300418h · 2012 · External reference
Ambertools
10.1021/acs.jcim.3c01153 · 2023 · External reference
10.1016/j.csbj.2021.09.003 · Admitted local publication
Interfacial dynamics and growth modes of β2-microglobulin dimers
10.1021/acs.jcim.3c00399 · 2023 · External reference
A genomic mutational constraint map using variation in 76,156 human genomes
2023 · External reference
Homozygous il37 mutation associated with infantile inflammatory bowel disease
2021 · External reference
Premps: predicting the effects of single mutations on protein stability
2020 · External reference
Molecular approaches to protein dimerization: opportunities for supramolecular chemistry
2022 · External reference
10.1016/j.tibs.2004.09.006
10.1016/j.tibs.2004.09.006 · External reference
Protein complexes: the evolution of symmetry
10.1016/j.cub.2008.11.004 · 2009 · External reference
Inference of macromolecular assemblies from crystalline state
10.1016/j.jmb.2007.05.022 · 2007 · External reference
10.1073/pnas.1810054115
10.1073/pnas.1810054115 · External reference
10.1111/febs.15717
10.1111/febs.15717 · External reference
To keep or not to keep? The question of crystallographic waters for enzyme simulations in organic solvent
10.1080/08927022.2016.1139108 · 2016 · External reference
10.1111/j.1742-4658.2007.06178.x
10.1111/j.1742-4658.2007.06178.x · External reference
10.1110/ps.073360508
10.1110/ps.073360508 · External reference
The protein common interface database (protcid)—a comprehensive database of interactions of homologous proteins in multiple crystal forms
2010 · External reference
A pdb-wide, evolution-based assessment of protein-protein interfaces
2014 · External reference
10.1107/s2052252514005442
10.1107/s2052252514005442 · External reference
Piqsi: protein quaternary structure investigation
10.1016/j.str.2007.09.019 · 2007 · External reference
Structural insights into the pro-apoptotic function of mitochondrial serine protease htra2/omi
10.1038/nsb795 · 2002 · External reference
The conserved lid tryptophan, w211, potentiates thermostability and thermoactivity in bacterial thermoalkalophilic lipases
2013 · External reference
The mm/pbsa and mm/gbsa methods to estimate ligand-binding affinities
10.1517/17460441.2015.1032936 · 2015 · External reference
