Research graph
References from Proteomics appending a complementary dimension to precision oncotherapy. Local targets link to admitted publications; unresolved targets remain external evidence.
The human genome project.
10.4065/mcp.2011.0160 · 2011 · External reference
New human gene tally reignites debate
10.1038/d41586-018-05462-w · 2018 · External reference
10.1056/nejme038132
10.1056/nejme038132 · External reference
10.1002/bmc.3157
10.1002/bmc.3157 · External reference
10.1038/s41588-020-0682-6
10.1038/s41588-020-0682-6 · External reference
10.1002/pro.3987
10.1002/pro.3987 · External reference
10.1038/nmeth.1333
10.1038/nmeth.1333 · External reference
10.1038/nmeth0910-681
10.1038/nmeth0910-681 · External reference
10.1586/14789450.2016.1159959
10.1586/14789450.2016.1159959 · External reference
10.1080/14789450.2017.1256776
10.1080/14789450.2017.1256776 · External reference
Statistical Assessment of QC Metrics on Raw LC-MS/MS Data
10.1007/978-1-4939-6747-6_22 · 2017 · External reference
10.1016/j.celrep.2014.07.036
10.1016/j.celrep.2014.07.036 · External reference
The CPTAC data portal: a resource for cancer proteomics research
10.1021/pr501254j · 2015 · External reference
10.1038/nature19949
10.1038/nature19949 · External reference
Revisiting biomarker discovery by plasma proteomics
10.15252/msb.20156297 · 2017 · External reference
10.1016/j.aca.2017.01.059
10.1016/j.aca.2017.01.059 · External reference
10.1038/nmeth.4116
10.1038/nmeth.4116 · External reference
Estimation of absolute protein quantities of unlabeled samples by selected reaction monitoring mass spectrometry
10.1074/mcp.m111.013987 · 2012 · External reference
Higher-energy C-trap dissociation for peptide modification analysis
10.1038/nmeth1060 · 2007 · External reference
10.1039/c8mo00126j
10.1039/c8mo00126j · External reference
Robustness and ruggedness of isoelectric focusing and superficially porous liquid chromatography with fourier transform mass spectrometry
10.1021/jasms.0c00355 · 2021 · External reference
10.1039/c9mo00154a
10.1039/c9mo00154a · External reference
Serological proteome analysis approach-based identification of ENO1 as a tumor-associated antigen and its autoantibody could enhance the sensitivity of CEA and CYFRA 21-1 in the detection of non-small cell lung cancer
10.18632/oncotarget.17067 · 2017 · External reference
Identification a novel clinical biomarker in early diagnosis of human non-small cell lung cancer
10.1007/s10719-018-09853-z · 2019 · External reference
Comparative proteomics reveals a diagnostic signature for pulmonary head-and-neck cancer metastasis
10.15252/emmm.201708428 · 2018 · External reference
Advances in aptamer-based biomarker discovery
2021 · External reference
10.1038/346818a0
10.1038/346818a0 · External reference
10.1586/erm.10.89
10.1586/erm.10.89 · External reference
10.1002/pmic.201300187
10.1002/pmic.201300187 · External reference
10.1038/nrd3141
10.1038/nrd3141 · External reference
10.1039/d2cc03628b
10.1039/d2cc03628b · External reference
Chlorin e6 conjugated interleukin-6 receptor aptamers selectively kill target cells upon irradiation
2014 · External reference
Antidote-mediated control of an anticoagulant aptamer in vivo
10.1038/nbt1023 · 2004 · External reference
10.1038/nm.1990
10.1038/nm.1990 · External reference
Identification and characterization of nuclease-stabilized RNA molecules that bind human prostate cancer cells via the prostate-specific membrane antigen
2002 · External reference
10.1016/j.bbrc.2014.09.023
10.1016/j.bbrc.2014.09.023 · External reference
Homogenous 96-plex PEA immunoassay exhibiting high sensitivity, specificity, and excellent scalability
10.1371/journal.pone.0095192 · 2014 · External reference
Homogeneous antibody-based proximity extension assays provide sensitive and specific detection of low-abundant proteins in human blood
10.1093/nar/gkr424 · 2011 · External reference
Proximity Extension Assay in Combination with Next-Generation Sequencing for High-throughput Proteome-wide Analysis
2021 · External reference
Detection of serological biomarkers by proximity extension assay for detection of colorectal neoplasias in symptomatic individuals
10.1186/1479-5876-11-253 · 2013 · External reference
Plasma Proteomic Analysis in Non-Small Cell Lung Cancer Patients Treated with PD-1/PD-L1 Blockade
10.3390/cancers13133116 · 2021 · External reference
Discovery of PTN as a serum-based biomarker of pro-metastatic prostate cancer
10.1038/s41416-020-01200-0 · 2021 · External reference
10.1016/s1535-6108(03)00086-2
10.1016/s1535-6108(03)00086-2 · External reference
10.1016/s1359-6446(05)03449-5
10.1016/s1359-6446(05)03449-5 · External reference
Antibody arrays in cancer research
10.1074/mcp.m500010-mcp200 · 2005 · External reference
xMAP Technology: Applications in Detection of Pathogens
10.3389/fmicb.2017.00055 · 2017 · External reference
Quantum dots-based reverse phase protein microarray
10.1016/j.talanta.2005.06.064 · 2005 · External reference
10.1039/c9nj02879j
10.1039/c9nj02879j · External reference
Protein microarrays for personalized medicine
10.1373/clinchem.2009.137158 · 2010 · External reference
10.1074/mcp.r120.001936
10.1074/mcp.r120.001936 · External reference
Identification of interleukin-8 as estrogen receptor-regulated factor involved in breast cancer invasion and angiogenesis by protein arrays
10.1002/ijc.11724 · 2004 · External reference
The analysis of doxorubicin resistance in human breast cancer cells using antibody microarrays
10.1158/1535-7163.mct-06-0190 · 2006 · External reference
Detection of pancreatic cancer using antibody microarray-based serum protein profiling
10.1002/pmic.200701167 · 2008 · External reference
10.1038/sj.onc.1204265
10.1038/sj.onc.1204265 · External reference
10.1016/j.molonc.2010.09.003
10.1016/j.molonc.2010.09.003 · External reference
Plasma biomarker discovery and validation for colorectal cancer by quantitative shotgun mass spectrometry and protein microarray
10.1111/j.1349-7006.2010.01818.x · 2011 · External reference
Predicting Cancer Cell Line Dependencies From the Protein Expression Data of Reverse-Phase Protein Arrays
2020 · External reference
Reverse phase protein array: validation of a novel proteomic technology and utility for analysis of primary leukemia specimens and hematopoietic stem cells
10.1158/1535-7163.mct-06-0334 · 2006 · External reference
Exosomes in Liquid Biopsy: The Nanometric World in the Pursuit of Precision Oncology
10.3390/cancers13092147 · 2021 · External reference
Proteomic analysis of circulating extracellular vesicles identifies potential markers of breast cancer progression, recurrence, and response
10.1126/sciadv.aba5714 · 2020 · External reference
Diagnostic and prognostic potential of the proteomic profiling of serum-derived extracellular vesicles in prostate cancer
10.1038/s41419-021-03909-z · 2021 · External reference
Reverse phase protein microarrays: fluorometric and colorimetric detection
10.1007/978-1-61779-043-0_18 · 2011 · External reference
Dual-Color, multiplex analysis of protein microarrays for precision medicine
10.1007/978-1-4939-6747-6_12 · 2017 · External reference
10.1016/j.cell.2019.03.005
10.1016/j.cell.2019.03.005 · External reference
Single-Cell Multiplexed Proteomics on the IsoLight Resolves Cellular Functional Heterogeneity to Reveal Clinical Responses of Cancer Patients to Immunotherapies
10.1007/978-1-4939-9773-2_19 · 2020 · External reference
Persistence of adoptively transferred T cells with a kinetically engineered IL-2 receptor agonist
10.1038/s41467-019-12901-3 · 2020 · External reference
10.1038/s41580-018-0094-y
10.1038/s41580-018-0094-y · External reference
10.1038/s41587-022-01302-5
10.1038/s41587-022-01302-5 · External reference
Identification of candidate diagnostic serum biomarkers for Kawasaki disease using proteomic analysis
10.1038/srep43732 · 2017 · External reference
10.1097/mpa.0000000000000388
10.1097/mpa.0000000000000388 · External reference
Urinary proteomics can define distinct diagnostic inflammatory arthritis subgroups
10.1038/srep40473 · 2017 · External reference
A neural network approach to multi-biomarker panel discovery by high-throughput plasma proteomics profiling of breast cancer
2013 · External reference
Artificial neural networks analysis of surface-enhanced laser desorption/ionization mass spectra of serum protein pattern distinguishes colorectal cancer from healthy population
10.1158/1078-0432.ccr-1162-03 · 2004 · External reference
Early detection of malignant pleural mesothelioma in asbestos-exposed individuals with a noninvasive proteomics-based surveillance tool
10.1371/journal.pone.0046091 · 2012 · External reference
10.1016/s0140-6736(02)07746-2
10.1016/s0140-6736(02)07746-2 · External reference
Serum biomarker panels for the diagnosis of gastric adenocarcinoma
10.1038/bjc.2011.592 · 2012 · External reference
Proteomic profiling of urinary proteins in renal cancer by surface enhanced laser desorption ionization and neural-network analysis: identification of key issues affecting potential clinical utility
2003 · External reference
Fast Support Vector Classification for Large-Scale Problems
10.1109/tpami.2021.3085969 · 2022 · External reference
10.1016/j.cels.2016.02.001
10.1016/j.cels.2016.02.001 · External reference
10.1038/75556
10.1038/75556 · External reference
10.1073/pnas.0506580102
10.1073/pnas.0506580102 · External reference
Phosphoproteomic analysis of interacting tumor and endothelial cells identifies regulatory mechanisms of transendothelial migration
10.1126/scisignal.aac5820 · 2016 · External reference
Pathway and network analysis of cancer genomes
10.1038/nmeth.3440 · 2015 · External reference
A novel signaling pathway impact analysis
10.1093/bioinformatics/btn577 · 2009 · External reference
10.1093/bioinformatics/btt471
10.1093/bioinformatics/btt471 · External reference
Associating genes and protein complexes with disease via network propagation
10.1371/journal.pcbi.1000641 · 2010 · External reference
10.1038/nmeth.2651
10.1038/nmeth.2651 · External reference
Identifying causal genes and dysregulated pathways in complex diseases
2011 · External reference
The power of protein interaction networks for associating genes with diseases
10.1093/bioinformatics/btq076 · 2010 · External reference
10.1158/0008-5472.can-17-0078
10.1158/0008-5472.can-17-0078 · External reference
10.1038/nbt0108-69
10.1038/nbt0108-69 · External reference
Sense and nonsense of pathway analysis software in proteomics
10.1021/pr200654k · 2011 · External reference
Consistency, comprehensiveness, and compatibility of pathway databases
10.1186/1471-2105-11-449 · 2010 · External reference
10.1002/pmic.200400869
10.1002/pmic.200400869 · External reference
Kinase-substrate enrichment analysis provides insights into the heterogeneity of signaling pathway activation in leukemia cells
10.1126/scisignal.2003573 · 2013 · External reference
10.1016/j.cell.2016.07.007
10.1016/j.cell.2016.07.007 · External reference
10.1093/bioinformatics/btq182
10.1093/bioinformatics/btq182 · External reference
10.1109/tpami.2014.2343973
10.1109/tpami.2014.2343973 · External reference
ClustVis: a web tool for visualizing clustering of multivariate data using Principal Component Analysis and heatmap
10.1093/nar/gkv468 · 2015 · External reference
Robust Matrix Factorization With Spectral Embedding
10.1109/tnnls.2020.3027351 · 2021 · External reference
Integrative clustering of multiple genomic data types using a joint latent variable model with application to breast and lung cancer subtype analysis
10.1093/bioinformatics/btp543 · 2009 · External reference
10.1186/1752-0509-7-14
10.1186/1752-0509-7-14 · External reference
10.1007/s11060-007-9383-6
10.1007/s11060-007-9383-6 · External reference
Support vector machine classification and validation of cancer tissue samples using microarray expression data
10.1093/bioinformatics/16.10.906 · 2000 · External reference
10.1101/gr.182601
10.1101/gr.182601 · External reference
10.1038/nbt.2940
10.1038/nbt.2940 · External reference
A multivariate approach to the integration of multi-omics datasets
10.1186/1471-2105-15-162 · 2014 · External reference
10.1038/nbt1010-1015
10.1038/nbt1010-1015 · External reference
OpenMS - A platform for reproducible analysis of mass spectrometry data
10.1016/j.jbiotec.2017.05.016 · 2017 · External reference
A repository of assays to quantify 10,000 human proteins by SWATH-MS
10.1038/sdata.2014.31 · 2014 · External reference
10.1038/nmeth.3954
10.1038/nmeth.3954 · External reference
10.1126/science.aah4115
10.1126/science.aah4115 · External reference
Streamlined single-cell proteomics by an integrated microfluidic chip and data-independent acquisition mass spectrometry
10.1038/s41467-021-27778-4 · 2022 · External reference
10.1016/j.cell.2014.04.005
10.1016/j.cell.2014.04.005 · External reference
Pomalidomide, cyclophosphamide, and dexamethasone for relapsed multiple myeloma
10.1182/blood-2018-07-863829 · 2018 · External reference
A systematic review of bevacizumab efficacy in breast cancer
10.1016/j.ctrv.2014.05.006 · 2014 · External reference
10.1016/j.cell.2016.05.069
10.1016/j.cell.2016.05.069 · External reference
10.1158/0008-5472.can-18-1079
10.1158/0008-5472.can-18-1079 · External reference
A proteomic landscape of diffuse-type gastric cancer
10.1038/s41467-018-03121-2 · 2018 · External reference
10.1016/j.ccell.2018.08.004
10.1016/j.ccell.2018.08.004 · External reference
Breast cancer quantitative proteome and proteogenomic landscape
10.1038/s41467-019-09018-y · 2019 · External reference
10.1016/j.cell.2020.10.036
10.1016/j.cell.2020.10.036 · External reference
10.1016/j.cell.2021.07.016
10.1016/j.cell.2021.07.016 · External reference
10.1016/j.cell.2019.10.007
10.1016/j.cell.2019.10.007 · External reference
The proteogenomic landscape of curable prostate cancer
10.1016/j.ccell.2019.02.005 · 2019 · External reference
Functional proteomic profiling analysis in four major types of gastrointestinal cancers
10.3390/biom13040701 · 2023 · External reference
Pan-cancer proteomic map of 949 human cell lines
10.1016/j.ccell.2022.06.010 · 2022 · External reference
Identifying prostate carcinoma by MALDI-Imaging
2007 · External reference
MALDI MS imaging as a powerful tool for investigating synovial tissue
10.3109/03009742.2011.647925 · 2012 · External reference
Tumor classification of six common cancer types based on proteomic profiling by MALDI imaging
10.1021/pr200784p · 2012 · External reference
Integrated Omics of Metastatic Colorectal Cancer
10.1016/j.ccell.2020.08.002 · 2020 · External reference
10.1002/hep.29291
10.1002/hep.29291 · External reference
Subtype-specific secretomic characterization of pulmonary neuroendocrine tumor cells
10.1038/s41467-019-11153-5 · 2019 · External reference
Prospective Identification of Elevated Circulating CDCP1 in Patients Years before Onset of Lung Cancer
10.1158/0008-5472.can-20-3454 · 2021 · External reference
Proteogenomic Characterization of Human Early-Onset Gastric Cancer
10.1016/j.ccell.2018.12.003 · 2019 · External reference
Integrated Proteomic and Glycoproteomic Characterization of Human High-Grade Serous Ovarian Carcinoma
2020 · External reference
Proteogenomic Characterization of Ovarian HGSC implicates mitotic kinases, replication stress in observed chromosomal instability
2020 · External reference
10.1016/j.cell.2020.05.043
10.1016/j.cell.2020.05.043 · External reference
10.1016/j.cell.2020.10.044
10.1016/j.cell.2020.10.044 · External reference
10.1016/j.celrep.2017.08.010
10.1016/j.celrep.2017.08.010 · External reference
Multi-omics Characterization of Interaction-mediated Control of Human Protein Abundance levels
10.1074/mcp.ra118.001280 · 2019 · External reference
Proteome stability as a key factor of genome integrity
10.3390/ijms18102036 · 2017 · External reference
Post-transcriptional screen of cancer amplified genes identifies ERBB2/Her2 signaling as AU-rich mRNA stability-promoting pathway
10.1038/s41389-021-00351-w · 2021 · External reference
10.1016/j.devcel.2019.06.003
10.1016/j.devcel.2019.06.003 · External reference
The role of Hippo pathway in ferroptosis
2022 · External reference
Assays Used for Discovering Small Molecule Inhibitors of YAP Activity in Cancers
10.3390/cancers14041029 · 2022 · External reference
MAP4K interactome reveals STRN4 as a Key STRIPAK complex component in hippo pathway regulation
2020 · External reference
10.1158/1078-0432.ccr-20-3752
10.1158/1078-0432.ccr-20-3752 · External reference
Antigenic essence: upgrade of cellular cancer vaccines
10.3390/cancers13040774 · 2021 · External reference
10.1038/s41587-021-01038-8
10.1038/s41587-021-01038-8 · External reference
Direct identification of clinically relevant neoepitopes presented on native human melanoma tissue by mass spectrometry
10.1038/ncomms13404 · 2016 · External reference
EGF receptor ligands
10.1016/s0014-4827(02)00105-2 · 2003 · External reference
10.1146/annurev.pharmtox.44.101802.121440
10.1146/annurev.pharmtox.44.101802.121440 · External reference
Involvement and targeted intervention of mortalin-regulated proteome phosphorylated-modification in hepatocellular Carcinoma
2021 · External reference
Phosphoproteomics reveals therapeutic targets of esophageal squamous cell carcinoma
10.1038/s41392-021-00682-5 · 2021 · External reference
10.1021/acs.jproteome.1c00331
10.1021/acs.jproteome.1c00331 · External reference
Chromatin proteomics to study epigenetics - challenges and opportunities
10.1074/mcp.r120.002208 · 2021 · External reference
10.1038/s41375-021-01235-z
10.1038/s41375-021-01235-z · External reference
10.1038/nature18003
10.1038/nature18003 · External reference
Omics-based molecular classifications empowering in precision oncology
2024 · External reference
10.1016/j.cell.2019.03.030
10.1016/j.cell.2019.03.030 · External reference
10.1016/j.cell.2020.01.026
10.1016/j.cell.2020.01.026 · External reference
10.1016/j.cell.2019.08.052
10.1016/j.cell.2019.08.052 · External reference
10.1016/j.cell.2020.06.013
10.1016/j.cell.2020.06.013 · External reference
10.1016/j.cell.2021.08.023
10.1016/j.cell.2021.08.023 · External reference
