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References from The complete catalog of antimicrobial resistance secondary active transporters in Clostridioides difficile : evolution and drug resistance perspective. Local targets link to admitted publications; unresolved targets remain external evidence.
The urgent threat of Clostridioides difficile infection: a glimpse of the drugs of the future, with related patents and prospects
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Unresolved reference
External reference
Clostridium difficile infection in oncology patients: epidemiology, pathophysiology, risk factors, diagnosis, and treatment
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Type 3 immunity during Clostridioides difficile infection: too much of a good thing?
10.1128/iai.00306-19 · 2019 · External reference
Unresolved reference
1997 · External reference
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10.1093/cid/ciy149 · 2018 · External reference
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2021 · External reference
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10.1042/ebc20160062 · External reference
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10.1056/nejmoa1602615 · External reference
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10.1007/s40121-020-00314-5 · 2020 · External reference
The efficacy of Bezlotoxumab in the prevention of recurrent Clostridium difficile: a systematic review
2022 · External reference
Real-world use of bezlotoxumab and fecal microbiota transplantation for the treatment of Clostridioides difficile infection
10.1093/ofid/ofad028 · 2023 · External reference
10.1016/j.cmi.2017.12.022
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Frontiers in antibiotic alternatives for Clostridioides difficile infection
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10.1038/s41579-018-0048-6 · External reference
10.1016/j.drup.2016.06.007
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CD2068 potentially mediates multidrug efflux in Clostridium difficile
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10.1016/j.csbj.2021.05.012 · External reference
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10.1002/pro.2820 · External reference
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2023 · External reference
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2022 · External reference
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Unresolved reference
2023 · External reference
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10.1093/molbev/mst010 · External reference
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10.1093/sysbio/syq010 · External reference
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10.1038/s41586-021-03819-2
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10.1002/9780470015902.a0003743.pub3
10.1002/9780470015902.a0003743.pub3 · External reference
Microarray analysis of the transcriptional responses of Clostridium difficile to environmental and antibiotic stress
10.1099/jmm.0.47657-0 · 2008 · External reference
Transcriptional profiling of Clostridium difficile and Caco-2 cells during infection
10.1086/653484 · 2010 · External reference
Comparative transcriptional analysis of clinically relevant heat stress response in Clostridium difficile strain 630
10.1371/journal.pone.0042410 · 2012 · External reference
Transcriptional analysis of temporal gene expression in germinating Clostridium difficile 630 endospores
10.1371/journal.pone.0064011 · 2013 · External reference
10.1016/j.bcp.2016.10.005
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Unresolved reference
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Unresolved reference
External reference
10.1016/s0022-2836(03)00662-4
10.1016/s0022-2836(03)00662-4 · External reference
Fidaxomicin: a novel macrocyclic antibiotic approved for treatment of Clostridium difficile infection
10.1093/cid/cir830 · 2012 · External reference
Mechanism of quinolone action and resistance
10.1021/bi5000564 · 2014 · External reference
10.1016/j.envpol.2022.120440
10.1016/j.envpol.2022.120440 · External reference
10.1038/ng1830
10.1038/ng1830 · External reference
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2004 · External reference
CdeA of Clostridium difficile, a new multidrug efflux transporter of the MATE family
10.1089/mdr.2004.10.191 · 2004 · External reference
10.1016/j.jmb.2021.166959
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The ZupT transporter plays an important role in zinc homeostasis and contributes to Salmonella enterica virulence
2014 · External reference
Zinc uptake system ZnuACB is essential for maintaining pathogenic phenotype of F4ac+ enterotoxigenic E. coli (ETEC) under a zinc restricted environment
10.1186/s13567-020-00854-1 · 2020 · External reference
Iron regulation in Clostridioides difficile
2018 · External reference
10.1093/nar/gkac963
10.1093/nar/gkac963 · External reference
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10.1002/pro.4792 · 2023 · External reference
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10.1016/j.celrep.2015.03.003 · External reference
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10.3389/fmicb.2019.02305 · 2019 · External reference
10.1038/ncomms7874
10.1038/ncomms7874 · External reference
Simulated drug efflux for the AbgT family of membrane transporters
10.1021/acs.jcim.1c00516 · 2021 · External reference
Update on antimicrobial resistance in Clostridium difficile: resistance mechanisms and antimicrobial susceptibility testing
10.1128/jcm.02250-16 · 2017 · External reference
Mechanisms of antibiotic resistance of Clostridioides difficile
10.1093/jac/dkab231 · 2021 · External reference
Antimicrobial resistance in Clostridioides difficile
10.1007/s10096-021-04311-5 · 2021 · External reference
10.2142/biophysics.3.37
10.2142/biophysics.3.37 · External reference
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10.1007/s00253-019-09873-1 · 2019 · External reference
10.1038/nrmicro1994
10.1038/nrmicro1994 · External reference
Structure and mechanism of RND-type multidrug efflux pumps
10.1002/9780470920541.ch1 · 2011 · External reference
Structural phylogenetics with confidence
10.1093/molbev/msaa100 · 2020 · External reference
AlphaFold and beyond
10.1038/s41592-023-01790-6 · 2023 · External reference
Clustering predicted structures at the scale of the known protein universe
10.1038/s41586-023-06510-w · 2023 · External reference
Uncovering new families and folds in the natural protein universe
10.1038/s41586-023-06622-3 · 2023 · External reference
In silico structural, functional and phylogenetic analyses of cellulase from Ruminococcus albus
10.1186/s43141-021-00162-x · 2021 · External reference
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10.3390/antibiotics11040520
10.3390/antibiotics11040520 · External reference
RND-type drug efflux pumps from gram-negative bacteria: molecular mechanism and inhibition
2015 · External reference
Distribution and spread of the mobilised RND efflux pump gene cluster tmexCD-toprJ in clinical gram-negative bacteria: a molecular epidemiological study
10.1016/s2666-5247(22)00221-x · 2022 · External reference
10.1002/j.1460-2075.1994.tb06340.x
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Phylogeny of multidrug transporters
10.1006/scdb.2000.0246 · 2001 · External reference
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2020 · External reference
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10.1093/molbev/msab139 · 2021 · External reference
Cossart P. HflXr, a homolog of a ribosome-splitting factor, mediates antibiotic resistance
10.1073/pnas.1810555115 · 2018 · External reference
Exploring the HME and HAE1 efflux systems in the genus Burkholderia
10.1186/1471-2148-10-164 · 2010 · External reference
Phylogenetic analysis reveals an ancient gene duplication as the origin of the MdtABC efflux pump
10.1371/journal.pone.0228877 · 2020 · External reference
Gene duplications in the genomes of Staphylococci and Enterococci
2020 · External reference
Structure and dynamics of the pan-genome of Streptococcus pneumoniae and closely related species
10.1186/gb-2010-11-10-r107 · 2010 · External reference
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Evaluation of candidate reference genes in Clostridium difficile for gene expression normalization
10.1016/j.anaerobe.2010.06.007 · 2010 · External reference
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1998 · External reference
The ins and outs of RND efflux pumps in Escherichia coli
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