References

10.3322/caac.21660

10.3322/caac.21660 · External reference

Circulating insulin-like growth factor-i concentrations and risk of 30 cancers: prospective analyses in UK biobank

10.1158/0008-5472.can-20-1281 · 2020 · External reference

10.1158/0008-5472.can-15-1551

10.1158/0008-5472.can-15-1551 · External reference

The impact of PIK3R1 mutations and insulin-PI3K-glycolytic pathway regulation in prostate cancer

10.1158/1078-0432.ccr-21-4272 · 2022 · External reference

PI3K/AKT/mTOR signaling participates in insulin-mediated regulation of pathological myopia-related factors in retinal pigment epithelial cells

10.1186/s12886-021-01946-y · 2021 · External reference

Insulin signaling pathway and related molecules: role in neurodegeneration and Alzheimer's disease

10.1016/j.neuint.2020.104707 · 2020 · External reference

Expression of IGF/insulin receptor in prostate cancer tissue and progression to lethal disease

10.1093/carcin/bgy112 · 2018 · External reference

Oncogenic functions of IGF1R and INSR in prostate cancer include enhanced tumor growth, cell migration and angiogenesis

10.18632/oncotarget.1884 · 2014 · External reference

Diverse functions of IGF/insulin signaling in malignant and noncancerous prostate cells: proliferation in cancer cells and differentiation in noncancerous cells

10.1210/en.2012-1348 · 2012 · External reference

Inceptor correlates with markers of prostate cancer progression and modulates insulin/IGF1 signaling and cancer cell migration

10.1016/j.molmet.2023.101706 · 2023 · External reference

10.1016/j.ccr.2011.04.008

10.1016/j.ccr.2011.04.008 · External reference

10.1111/obr.12674

10.1111/obr.12674 · External reference

10.1002/ijc.24202

10.1002/ijc.24202 · External reference

10.1158/0008-5472.can-11-1601

10.1158/0008-5472.can-11-1601 · External reference

Limitation of the validity of the homeostasis model assessment as an index of insulin resistance in Korea

10.1016/j.metabol.2004.08.014 · 2005 · External reference

Use and abuse of HOMA modeling

10.2337/diacare.27.6.1487 · 2004 · External reference

Mendelian randomization as an approach to assess causality using observational data

10.1681/asn.2016010098 · 2016 · External reference

10.1038/s41588-021-00852-9

10.1038/s41588-021-00852-9 · External reference

Meta-analysis of gene-environment interaction: joint estimation of SNP and SNP × environment regression coefficients

10.1002/gepi.20546 · 2011 · External reference

Loci for insulin processing and secretion provide insight into type 2 diabetes risk

10.1016/j.ajhg.2023.01.002 · 2023 · External reference

Genome-wide association identifies nine common variants associated with fasting proinsulin levels and provides new insights into the pathophysiology of type 2 diabetes

10.2337/db11-0415 · 2011 · External reference

Unresolved reference

External reference

Association analyses of more than 140,000 men identify 63 new prostate cancer susceptibility loci

10.1038/s41588-018-0142-8 · 2018 · External reference

Mendelian randomization analysis as a tool to gain insights into causes of diseases: a primer

10.1681/asn.2020121760 · 2021 · External reference

10.1093/eurheartj/ehad736

10.1093/eurheartj/ehad736 · External reference

Physical activity and risks of breast and colorectal cancer: a Mendelian randomisation analysis

10.1038/s41467-020-14389-8 · 2020 · External reference

Mendelian randomization with invalid instruments: effect estimation and bias detection through Egger regression

10.1093/ije/dyv080 · 2015 · External reference

Assessing the suitability of summary data for two-sample Mendelian randomization analyses using MR-Egger regression: the role of the I2 statistic

2016 · External reference

10.1038/s41588-017-0009-4

10.1038/s41588-017-0009-4 · External reference

A framework for the investigation of pleiotropy in two-sample summary data Mendelian randomization

10.1002/sim.7221 · 2017 · External reference

Improving the accuracy of two-sample summary-data Mendelian randomization: moving beyond the NOME assumption

10.1093/ije/dyy258 · 2019 · External reference

The use of two-sample methods for Mendelian randomization analyses on single large datasets

10.1093/ije/dyab084 · 2021 · External reference

Unresolved reference

External reference

Multivariable mendelian randomization and mediation

10.1101/cshperspect.a038984 · 2021 · External reference

An examination of multivariable Mendelian randomization in the single-sample and two-sample summary data settings

10.1093/ije/dyy262 · 2019 · External reference

Extending the MR-Egger method for multivariable Mendelian randomization to correct for both measured and unmeasured pleiotropy

10.1002/sim.7492 · 2017 · External reference

Pleiotropy robust methods for multivariable Mendelian randomization

10.1002/sim.9156 · 2021 · External reference

10.1038/s41568-020-0295-5

10.1038/s41568-020-0295-5 · External reference

Insulin resistance and cancer risk: an overview of the pathogenetic mechanisms

10.1155/2012/789174 · 2012 · External reference

10.1016/j.tem.2006.06.007

10.1016/j.tem.2006.06.007 · External reference

10.1002/pros.20852

10.1002/pros.20852 · External reference

Insulin receptor isoform variations in prostate cancer cells

10.3389/fendo.2016.00132 · 2016 · External reference

10.1038/bjc.2017.337

10.1038/bjc.2017.337 · External reference

10.1158/1541-7786.mcr-15-0279

10.1158/1541-7786.mcr-15-0279 · External reference

Serum insulin, glucose, indices of insulin resistance, and risk of prostate cancer

10.1093/jnci/djp260 · 2009 · External reference

Insulinemic and inflammatory dietary patterns and risk of prostate cancer

10.1016/j.eururo.2020.12.030 · 2021 · External reference

Genome-wide association study of the modified stumvoll insulin sensitivity index identifies BCL2 and FAM19A2 as novel insulin sensitivity loci

10.2337/db16-0199 · 2016 · External reference

Insulin resistance is inversely related to prostate cancer: a prospective study in Northern Sweden

10.1002/ijc.22587 · 2007 · External reference

Proinsulin binds with high affinity the insulin receptor isoform A and predominantly activates the mitogenic pathway

10.1210/en.2011-1843 · 2012 · External reference

Exome array analysis identifies new loci and low-frequency variants influencing insulin processing and secretion

10.1038/ng.2507 · 2013 · External reference

IG20/MADD plays a critical role in glucose-induced insulin secretion

10.2337/db13-0707 · 2014 · External reference

10.1016/j.ajhg.2013.12.011

10.1016/j.ajhg.2013.12.011 · External reference

Shear stress triggered circular dorsal ruffles formation to facilitate cancer cell migration

2021 · External reference

Nucleolin lactylation contributes to intrahepatic cholangiocarcinoma pathogenesis via RNA splicing regulation of MADD

2024 · External reference