Research graph
References from Transcriptomic investigations of polymyxins and colistin/sulbactam combination against carbapenem-resistant Acinetobacter baumannii. Local targets link to admitted publications; unresolved targets remain external evidence.
WHO publishes list of bacteria for which new antibiotics are urgently needed
10.17712/1658-3183.2290 · 2017 · External reference
Unresolved reference
External reference
Global challenge of multidrug-resistant Acinetobacter baumannii
10.1128/aac.01464-06 · 2007 · External reference
Antibiotic usage and resistance: gaining or losing ground on infections in critically ill patients?
10.1001/jama.2009.1774 · 2009 · External reference
Emergent polymyxin resistance: end of an era?
10.1093/ofid/ofz368 · 2019 · External reference
10.1007/978-3-030-16373-0_17
10.1007/978-3-030-16373-0_17 · 2019 · External reference
Incidence and predictors of acute kidney injury associated with intravenous polymyxin B therapy
10.1016/j.jinf.2012.01.015 · 2012 · External reference
International consensus guidelines for the optimal use of the polymyxins: endorsed by the American College of Clinical Pharmacy (ACCP), European Society of Clinical Microbiology and Infectious Diseases (ESCMID), Infectious Diseases Society of America (IDSA), International Society for Anti-infective Pharmacology (ISAP), Society of Critical Care Medicine (SCCM), and Society of Infectious Diseases Pharmacists (SIDP)
10.1002/phar.2209 · 2019 · External reference
Comparative efficacy and safety of treatment options for MDR and XDR Acinetobacter baumannii infections: a systematic review and network meta-analysis
10.1093/jac/dkx368 · 2018 · External reference
Enhanced bacterial killing with colistin/sulbactam combination against carbapenem-resistant Acinetobacter baumannii
10.1016/j.ijantimicag.2020.106271 · 2021 · External reference
10.1007/978-3-030-16373-0_3
10.1007/978-3-030-16373-0_3 · 2019 · External reference
Unresolved reference
External reference
Clinical pharmacokinetics and pharmacodynamics of colistin
10.1007/s40262-017-0561-1 · 2017 · External reference
Contemporary activity of colistin and polymyxin B against a worldwide collection of Gram-negative pathogens: results from the SENTRY Antimicrobial Surveillance Program (2006-09)
10.1093/jac/dkr239 · 2011 · External reference
10.1016/j.ijantimicag.2004.10.001
10.1016/j.ijantimicag.2004.10.001 · External reference
Pharmacology of polymyxins: new insights into an 'old' class of antibiotics
10.2217/fmb.13.39 · 2013 · External reference
10.1093/jb/mvp096
10.1093/jb/mvp096 · External reference
10.1038/ja.2013.111
10.1038/ja.2013.111 · External reference
10.1007/978-3-030-16373-0_4
10.1007/978-3-030-16373-0_4 · 2019 · External reference
Metabolomics as a tool for drug discovery and personalised medicine. A review
10.2174/1568026614666141215124956 · 2014 · External reference
10.1128/aac.02109-15
10.1128/aac.02109-15 · External reference
10.1128/jb.00481-08
10.1128/jb.00481-08 · External reference
10.1371/journal.pone.0005660
10.1371/journal.pone.0005660 · External reference
The OprB porin plays a central role in carbohydrate uptake in Pseudomonas aeruginosa
10.1128/jb.177.11.3021-3026.1995 · 1995 · External reference
A novel type of N-acetylglutamate synthase is involved in the first step of arginine biosynthesis in Corynebacterium glutamicum
10.1186/1471-2164-14-713 · 2013 · External reference
Outer membrane protein A (OmpA) as a potential therapeutic target for Acinetobacter baumannii infection
10.1186/s12929-020-0617-7 · 2020 · External reference
The gdhB gene of Pseudomonas aeruginosa encodes an arginine-inducible NAD(+)-dependent glutamate dehydrogenase which is subject to allosteric regulation
10.1128/jb.183.2.490-499.2001 · 2001 · External reference
The glutamate dehydrogenase gene gdhA increased the resistance of tobacco to glufosinate
10.1111/j.1365-3180.2004.00411.x · 2004 · External reference
10.1016/j.micpath.2014.11.005
10.1016/j.micpath.2014.11.005 · External reference
10.1101/cshperspect.a000414
10.1101/cshperspect.a000414 · External reference
10.1039/d0mo00015a
10.1039/d0mo00015a · External reference
Polymyxin resistance in Acinetobacter baumannii: genetic mutations and transcriptomic changes in response to clinically relevant dosage regimens
10.1038/srep26233 · 2016 · External reference
10.1093/jac/dku536
10.1093/jac/dku536 · External reference
10.1016/j.csbj.2022.02.021 · Admitted local publication
Comparative metabolomics and transcriptomics reveal multiple pathways associated with polymyxin killing in Pseudomonas aeruginosa
2019 · External reference
Overproduction of outer membrane protein A by Acinetobacter baumannii as a risk factor for nosocomial pneumonia, bacteremia, and mortality rate increase
2017 · External reference
10.3389/fmicb.2020.589234
10.3389/fmicb.2020.589234 · External reference
Distinct role of outer membrane protein A in the intrinsic resistance of Acinetobacter baumannii and Acinetobacter nosocomialis
10.1016/j.meegid.2018.10.022 · 2019 · External reference
Rapid detection of antibiotic resistance in Acinetobacter baumannii using quantitative real-time PCR
10.1093/jac/dkt057 · 2013 · External reference
10.1126/scitranslmed.abj0716
10.1126/scitranslmed.abj0716 · External reference
Physiological roles of trehalose in bacteria and yeasts: a comparative analysis
10.1007/s002030000192 · 2000 · External reference
10.1016/j.redox.2017.09.007
10.1016/j.redox.2017.09.007 · External reference
Molecular mechanisms of sulbactam antibacterial activity and resistance determinants in Acinetobacter baumannii.
10.1128/aac.04808-14 · 2015 · External reference
Bactericidal effect of sulbactam against Acinetobacter baumannii ATCC 19606 studied by 2D-DIGE and mass spectrometry
10.1016/j.ijantimicag.2014.03.004 · 2014 · External reference
10.1128/jb.00647-09
10.1128/jb.00647-09 · External reference
Contribution of biofilm formation genetic locus, pgaABCD, to antibiotic resistance development in gut microbiome
2020 · External reference
Epidemiological and genomic characteristics of Acinetobacter baumannii from different infection sites using comparative genomics
10.1186/s12864-021-07842-5 · 2021 · External reference
Unresolved reference
External reference
10.1038/nmeth.1923
10.1038/nmeth.1923 · External reference
Unresolved reference
External reference
Controlling the false discovery rate: a practical and powerful approach to multiple testing
10.1111/j.2517-6161.1995.tb02031.x · 1995 · External reference
jvenn: an interactive Venn diagram viewer
10.1186/1471-2105-15-293 · 2014 · External reference
10.1093/nar/gkm321
10.1093/nar/gkm321 · External reference
10.1089/omi.2011.0118
10.1089/omi.2011.0118 · External reference
10.1093/nar/28.1.33
10.1093/nar/28.1.33 · External reference
10.1093/molbev/msab293
10.1093/molbev/msab293 · External reference
10.1006/meth.2001.1262
10.1006/meth.2001.1262 · External reference
Synergistic killing of NDM-producing MDR Klebsiella pneumoniae by two 'old' antibiotics-polymyxin B and chloramphenicol
10.1093/jac/dkv135 · 2015 · External reference
Contemporaneous measurement of outer and Inner membrane permeability in Gram-negative bacteria
2020 · External reference