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References from CRCDB: A comprehensive database for integrating and analyzing multi-omics data of early-onset and late-onset colorectal cancer. Local targets link to admitted publications; unresolved targets remain external evidence.
10.3322/caac.21660
10.3322/caac.21660 · External reference
10.3322/caac.21772
10.3322/caac.21772 · External reference
Young-onset colorectal cancer
10.1038/s41572-023-00432-7 · 2023 · External reference
Germline genetic features of young individuals with colorectal cancer
10.1053/j.gastro.2017.11.004 · 2018 · External reference
Prevalence and spectrum of germline cancer susceptibility gene mutations among patients with early-onset colorectal cancer
10.1001/jamaoncol.2016.5194 · 2017 · External reference
An update on the epidemiology, molecular characterization, diagnosis, and screening strategies for early-onset colorectal cancer
10.1053/j.gastro.2020.12.068 · 2021 · External reference
10.1038/nm.3967
10.1038/nm.3967 · External reference
Young-onset colorectal cancer
10.1038/s41572-023-00432-7 · 2023 · External reference
Epigenetically regulated gene expression profiles reveal four molecular subtypes with prognostic and therapeutic implications in colorectal cancer
10.1093/bib/bbaa309 · 2021 · External reference
Unsupervised construction of gene regulatory network based on single-cell multi-omics data of colorectal cancer
10.1093/bib/bbad011 · 2023 · External reference
10.1093/nar/gkv1097
10.1093/nar/gkv1097 · External reference
CBD, a biomarker database for colorectal cancer
2018 · External reference
10.1093/bioinformatics/btr709
10.1093/bioinformatics/btr709 · External reference
10.1038/nmeth.3337
10.1038/nmeth.3337 · External reference
10.7717/peerj.11321
10.7717/peerj.11321 · External reference
Distinct expression and prognostic value of MS4A in gastric cancer
10.1515/med-2018-0028 · 2018 · External reference
Development of a phagocytosis-dependent gene signature to predict prognosis and response to checkpoint inhibition in clear-cell renal cell carcinoma
10.3389/fimmu.2022.853088 · 2022 · External reference
Interleukin-17 promotes prostate cancer via MMP7-induced epithelial-to-mesenchymal transition
10.1038/onc.2016.240 · 2017 · External reference
Sulforaphene inhibits esophageal cancer progression via suppressing SCD and CDH3 expression, and activating the GADD45B-MAP2K3-p38-p53 feedback loop
10.1038/s41419-020-02859-2 · 2020 · External reference
Keratin 23 is a peroxisome proliferator-activated receptor alpha-dependent, MYC-amplified oncogene that promotes hepatocyte proliferation
10.1002/hep.30530 · 2019 · External reference
Claudin-1 regulates intestinal epithelial homeostasis through the modulation of Notch-signalling
10.1136/gutjnl-2012-304241 · 2014 · External reference
CD177 modulates the function and homeostasis of tumor-infiltrating regulatory T cells
10.1038/s41467-021-26091-4 · 2021 · External reference
MCU-induced mitochondrial calcium uptake promotes mitochondrial biogenesis and colorectal cancer growth
10.1038/s41392-020-0155-5 · 2020 · External reference
Diagnosis and management of rectal cancer in patients younger than 50 years: rising global incidence and unique challenges
10.6004/jnccn.2022.7056 · 2022 · External reference
A novel protein encoded by circINSIG1 reprograms cholesterol metabolism by promoting the ubiquitin-dependent degradation of INSIG1 in colorectal cancer
10.1186/s12943-023-01773-3 · 2023 · External reference
Molecular residual disease and efficacy of adjuvant chemotherapy in patients with colorectal cancer
10.1038/s41591-022-02115-4 · 2023 · External reference
Promise and perils of blood-based signatures for detecting early-onset colorectal cancer
10.1053/j.gastro.2022.08.011 · 2022 · External reference
A liquid biopsy signature for the detection of patients with early-onset colorectal cancer
10.1053/j.gastro.2022.06.089 · 2022 · External reference
Proteomic profiling of colorectal adenomas identifies a predictive risk signature for development of metachronous advanced colorectal Neoplasia
2023 · External reference
Integrated metagenomic and metabolomic analysis reveals distinct gut-microbiome-derived phenotypes in early-onset colorectal cancer
10.1136/gutjnl-2022-327156 · 2023 · External reference
Hydroxyphenylpyruvate Dioxygenase is a metabolic immune checkpoint for UTX-deficient colorectal cancer
2023 · External reference