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References from Generation and characterization of two acid-resistant macrocin O -methyltransferase variants with a higher enzyme activity at 30 °C from Streptomyces fradiae. Local targets link to admitted publications; unresolved targets remain external evidence.
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Terminal stages in the biosynthesis of tylosin
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Properties of S-adenosyl-L-methionine:macrocin O-methyltransferase in extracts of Streptomyces fradiae strains which produce normal or elevated levels of tylosin and in mutants blocked in specific O-methylations
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Directed evolution of TetR for constructing sensitive and broad-spectrum tetracycline antibiotics whole-cell biosensor
2023 · External reference
Hot spots-making directed evolution easier
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An efficient one-step site-directed and site-saturation mutagenesis protocol
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A high-throughput method based on microculture technology for screening of high-yield strains of tylosin-producing Streptomyces fradiae
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Consistency evaluation between matrix components ratio and microbiological potency of tylosin major components
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Deciphering key features in protein structures with the new ENDscript server
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The I-TASSER suite: protein structure and function prediction
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Yield-determining factors in high-solids enzymatic hydrolysis of lignocellulose
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10.1002/anie.200352626 · 2004 · External reference
Structural basis of substrate specificity and regiochemistry in the MycF/TylF family of sugar O-methyltransferases
10.1021/cb5009348 · 2015 · External reference
SAM (dependent) I AM: the S-adenosylmethionine-dependent methyltransferase fold
10.1016/s0959-440x(02)00391-3 · 2002 · External reference
The crystal structure of the novobiocin biosynthetic enzyme NovP: the first representative structure for the TylF O-methyltransferase superfamily
10.1016/j.jmb.2009.10.045 · 2010 · External reference
Adaptive steered molecular dynamics combined with protein structure networks revealing the mechanism of Y68I/G109P mutations that enhance the catalytic activity of d-psicose 3-epimerase from Clostridium bolteae
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Thermostability improvement of a streptomyces xylanase by introducing proline and glutamic acid residues
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Ultrasound enhanced butyric acid-lauric acid designer lipid synthesis: based on artificial neural network and changes in enzymatic structure
2022 · External reference
Select human cancer mutants of NRMT1 alter its catalytic activity and decrease N-terminal trimethylation
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