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References from In silico structural studies on the vesicular neutral amino acid transporter NTT4 (SLC6A17). Local targets link to admitted publications; unresolved targets remain external evidence.
Characterization of the transporterB0AT3 (Slc6a17) in the rodent central nervous system
2013 · External reference
Importance of glutamine in synaptic vesicles revealed by functional studies of SLC6A17 and its mutations pathogenic for intellectual disability
2023 · External reference
Synaptic vesicle protein NTT4/XT1 (SLC6A17) catalyzes Na+-coupled neutral amino acid transport
10.1074/jbc.m806407200 · 2009 · External reference
10.1124/mol.108.050005
10.1124/mol.108.050005 · External reference
Homozygous SLC6A17 mutations cause autosomal-recessive intellectual disability with progressive tremor, speech impairment, and behavioral problems
10.1016/j.ajhg.2015.01.010 · 2015 · External reference
10.3109/10253890.2015.1105211
10.3109/10253890.2015.1105211 · External reference
The SLC6A15-SLC6A20 neutral amino acid transporter subfamily: functions, diseases, and their therapeutic relevance
10.1124/pharmrev.123.000886 · 2023 · External reference
B0AT2 (SLC6A15) Is localized to neurons and astrocytes, and is involved in mediating the effect of leucine in the brain
2013 · External reference
10.1006/geno.2000.6387
10.1006/geno.2000.6387 · External reference
The orphan transporter v7-3 (slc6a15) is a Na+-dependent neutral amino acid transporter (B0AT2)
10.1042/bj20051273 · 2006 · External reference
10.1016/j.bbrc.2005.09.128
10.1016/j.bbrc.2005.09.128 · External reference
10.1038/s41586-021-03819-2
10.1038/s41586-021-03819-2 · External reference
Principles of alternating access in leut-fold transporters: commonalities and divergences
10.1016/j.jmb.2022.167746 · 2022 · External reference
Structure and function of the SIT1 proline transporter in complex with the COVID-19 receptor ACE2
10.1038/s41467-024-48921-x · 2024 · External reference
10.1101/2020.02.19.956946
10.1101/2020.02.19.956946 · External reference
Structures of ACE2–SIT1 recognized by Omicron variants of SARS-CoV-2
10.1038/s41421-022-00488-x · 2022 · External reference
Structural insight into the substrate recognition and transport mechanism of amino acid transporter complex ACE2-B0AT1 and ACE2-SIT1
2023 · External reference
Probing binding and occlusion of substrate in the human creatine transporter-1 by computation and mutagenesis
10.1002/pro.4842 · 2024 · External reference
Structure and gating dynamics of Na+/Cl– coupled neurotransmitter transporters
10.3389/fmolb.2019.00080 · 2019 · External reference
10.1038/nature03978
10.1038/nature03978 · External reference
10.1074/jbc.m311579200
10.1074/jbc.m311579200 · External reference
10.1074/jbc.m809423200
10.1074/jbc.m809423200 · External reference
Steady-state kinetic characterization of the mouse B0AT1 sodium-dependent neutral amino acid transporter
10.1007/s00424-005-1455-x · 2005 · External reference
10.1038/nature17629
10.1038/nature17629 · External reference
10.1038/nature06038
10.1038/nature06038 · External reference
10.1126/science.1166777
10.1126/science.1166777 · External reference
A non‐helical region in transmembrane helix 6 of hydrophobic amino acid transporter MhsT mediates substrate recognition
10.15252/embj.2020105164 · 2021 · External reference
10.1038/s41594-023-01011-w
10.1038/s41594-023-01011-w · External reference
Loratadine and analogues: Discovery and preliminary structure-activity relationship of inhibitors of the amino acid transporter B0AT2
10.1021/jm501086v · 2014 · External reference
Effects of prednisolone on the pharmacokinetics of loratadine after oral and intravenous administration of loratadine in rats
10.1007/s12272-010-0913-y · 2010 · External reference
Brain histamine H1 receptor occupancy after oral administration of desloratadine and loratadine
10.1002/prp2.499 · 2019 · External reference
10.1038/s41586-022-04814-x
10.1038/s41586-022-04814-x · External reference