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References from Toxicogenomic assessment of in vitro macrophages exposed to profibrotic challenge reveals a sustained transcriptomic immune signature. Local targets link to admitted publications; unresolved targets remain external evidence.
Occupational exposures and IPF: when the dust unsettles
10.1136/thoraxjnl-2020-215567 · 2020 · External reference
The occupational burden of nonmalignant respiratory diseases. an official american thoracic society and european respiratory society statement
10.1164/rccm.201904-0717st · 2019 · External reference
10.1016/j.impact.2023.100476
10.1016/j.impact.2023.100476 · External reference
Mechanisms of carbon nanotube-induced pulmonary fibrosis: a physicochemical characteristic perspective
10.1002/wnan.1498 · 2018 · External reference
10.1016/j.cell.2021.11.033
10.1016/j.cell.2021.11.033 · External reference
Covid-19 acute responses and possible long term consequences: what nanotoxicology can teach us
10.1016/j.nantod.2020.100945 · 2020 · External reference
Bleomycin in the setting of lung fibrosis induction: from biological mechanisms to counteractions
10.1016/j.phrs.2015.04.012 · 2015 · External reference
10.1016/s0140-6736(17)30866-8
10.1016/s0140-6736(17)30866-8 · External reference
10.1056/nejmra1705751
10.1056/nejmra1705751 · External reference
10.1172/jci143226
10.1172/jci143226 · External reference
The role of immune and inflammatory cells in idiopathic pulmonary fibrosis
10.3389/fmed.2018.00043 · 2018 · External reference
10.1513/annalsats.201406-240mg
10.1513/annalsats.201406-240mg · External reference
Turnover of type I and III collagen predicts progression of idiopathic pulmonary fibrosis
10.1186/s12931-021-01801-0 · 2021 · External reference
10.1164/rccm.201507-1376oc
10.1164/rccm.201507-1376oc · External reference
The emerging roles of interstitial macrophages in pulmonary fibrosis: a perspective from scRNA-seq analyses
2022 · External reference
10.1084/jem.20162152
10.1084/jem.20162152 · External reference
Protection from pulmonary fibrosis in the absence of CCR2 signaling
2001 · External reference
10.1093/intimm/dxab040
10.1093/intimm/dxab040 · External reference
Transforming growth factor-β: master regulator of the respiratory system in health and disease
10.1165/rcmb.2015-0391tr · 2016 · External reference
10.1513/pats.201203-023aw
10.1513/pats.201203-023aw · External reference
10.1084/jem.20092121
10.1084/jem.20092121 · External reference
10.1016/j.ajpath.2013.09.007
10.1016/j.ajpath.2013.09.007 · External reference
M-1/M-2 macrophages and the Th1/Th2 paradigm
2000 · External reference
10.1016/j.immuni.2014.01.006
10.1016/j.immuni.2014.01.006 · External reference
Single-cell RNA-seq reveals ectopic and aberrant lung-resident cell populations in idiopathic pulmonary fibrosis
10.1126/sciadv.aba1983 · 2020 · External reference
10.1164/rccm.201712-2410oc
10.1164/rccm.201712-2410oc · External reference
10.1152/ajplung.00451.2020
10.1152/ajplung.00451.2020 · External reference
Proliferating SPP1/MERTK-expressing macrophages in idiopathic pulmonary fibrosis
10.1183/13993003.02441-2018 · 2019 · External reference
Bleomycin pulmonary toxicity has a negative impact on the outcome of patients with hodgkin’s lymphoma
10.1200/jco.2005.02.7243 · 2005 · External reference
Reich SD. Drugs five years later: bleomycin
10.7326/0003-4819-90-6-945 · 1979 · External reference
Bleomycin use in the treatment of Hodgkin lymphoma (HL): toxicity and outcomes in the modern era
10.1080/10428194.2019.1663419 · 2020 · External reference
Bleomycin pharmacology: mechanism of action and resistance, and clinical pharmacokinetics
1992 · External reference
The role of redox-active metals in the mechanism of action of bleomycin
10.1016/0009-2797(90)90001-4 · 1990 · External reference
Bleomycin induces molecular changes directly relevant to idiopathic pulmonary fibrosis: a model for “active” disease
2013 · External reference
Models of pulmonary fibrosis
10.1016/j.ddmod.2006.09.006 · 2006 · External reference
Repetitive intratracheal bleomycin models several features of idiopathic pulmonary fibrosis
10.1152/ajplung.00026.2010 · 2010 · External reference
10.1016/j.intimp.2014.08.002
10.1016/j.intimp.2014.08.002 · External reference
THP-1 cells as a model for human monocytes
10.21037/atm.2016.08.53 · 2016 · External reference
BMDx: a graphical Shiny application to perform Benchmark Dose analysis for transcriptomics data
10.1093/bioinformatics/btaa030 · 2020 · External reference
A method to integrate benchmark dose estimates with genomic data to assess the functional effects of chemical exposure
10.1093/toxsci/kfm092 · 2007 · External reference
Well plate maker: a user-friendly randomized block design application to limit batch effects in large-scale biomedical studies
10.1093/bioinformatics/btab065 · 2021 · External reference
Unresolved reference
External reference
Unresolved reference
External reference
10.1038/nmeth.3317
10.1038/nmeth.3317 · External reference
10.1093/bioinformatics/btp352
10.1093/bioinformatics/btp352 · External reference
10.1093/bioinformatics/btt656
10.1093/bioinformatics/btt656 · External reference
Data quality aware analysis of differential expression in RNA-seq with NOISeq R/Bioc package
10.1093/nar/gkv711 · 2015 · External reference
10.1186/s13059-014-0550-8
10.1186/s13059-014-0550-8 · External reference
10.1089/omi.2011.0118
10.1089/omi.2011.0118 · External reference
10.1186/gb-2002-3-7-research0034 · 2002 · Admitted local publication
10.1186/1471-2164-13-296
10.1186/1471-2164-13-296 · External reference
Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) Method
10.1006/meth.2001.1262 · 2001 · External reference
10.1126/science.abl4896
10.1126/science.abl4896 · External reference
10.1093/bib/bbaa417
10.1093/bib/bbaa417 · External reference
DFP: a Bioconductor package for fuzzy profile identification and gene reduction of microarray data
10.1186/1471-2105-10-37 · 2009 · External reference
DisGeNET: a discovery platform for the dynamical exploration of human diseases and their genes
2015 · External reference
10.1093/nar/gkac1010
10.1093/nar/gkac1010 · External reference
10.1093/nar/gkac1046
10.1093/nar/gkac1046 · External reference
10.1093/nar/gkz805
10.1093/nar/gkz805 · External reference
10.1183/09031936.00161910
10.1183/09031936.00161910 · External reference
Macrophage activation in acute exacerbation of idiopathic pulmonary fibrosis
10.1371/journal.pone.0116775 · 2015 · External reference
10.1126/science.aau0964
10.1126/science.aau0964 · External reference
T cells in idiopathic pulmonary fibrosis: crucial but controversial
2023 · External reference
10.1016/j.ajpath.2010.11.055
10.1016/j.ajpath.2010.11.055 · External reference
10.1073/pnas.1701237115
10.1073/pnas.1701237115 · External reference
10.1016/j.rmed.2019.08.003
10.1016/j.rmed.2019.08.003 · External reference
IP-10 mediates selective mononuclear cell accumulation and activation in response to intrapulmonary transgenic expression and during adenovirus-induced pulmonary inflammation
10.1089/jir.2005.25.103 · 2005 · External reference
10.1016/j.biocel.2007.11.020
10.1016/j.biocel.2007.11.020 · External reference
Role of matrix metalloproteinases in the pathogenesis of idiopathic pulmonary fibrosis
10.1186/s12931-016-0343-6 · 2016 · External reference
Contribution of the anaphylatoxin receptors, C3aR and C5aR, to the pathogenesis of pulmonary fibrosis
10.1096/fj.201500044 · 2016 · External reference
Potential mechanisms underlying TGF-β-mediated complement activation in lung fibrosis
10.21767/2573-5365.100037 · 2017 · External reference
10.1016/j.csbj.2024.08.018 · Admitted local publication
Toxicogenomics data for chemical safety assessment and development of new approach methodologies: an adverse outcome pathway-based approach
10.1002/advs.202203984 · 2023 · External reference