Research graph
References from Homology-based identification and structural analysis of Pangasius hypophthalmus Annexins and Serine proteases to search molecules for wound healing applications. Local targets link to admitted publications; unresolved targets remain external evidence.
Burn injury
2020 · External reference
Prevalence of chronic skin wounds and their risk factors in an inpatient hospital setting in Northern China
10.1097/01.asw.0000694164.34068.82 · 2020 · External reference
The financial and quality-of-life cost to patients living with a chronic wound in the community
10.1111/iwj.12767 · 2017 · External reference
Chronic wound management: from gauze to homologous cellular matrix
2023 · External reference
10.3892/br.2020.1300
10.3892/br.2020.1300 · External reference
Role, development, and value of enzymatic debridement as integral component in initial treatment of burn injuries exemplified by NexoBrid®
2022 · External reference
Clinical and economic benefit of enzymatic debridement of pressure ulcers compared to autolytic debridement with a hydrogel dressing
10.3111/13696998.2013.807268 · 2013 · External reference
Chronic wounds: Treatment consensus
10.1111/wrr.12994 · 2022 · External reference
Enzymatic debridement: past, present, and future
2022 · External reference
State of the art in enzymatic debridement
10.20517/2347-9264.2018.46 · 2018 · External reference
Drug discovery from natural products – Old problems and novel solutions for the treatment of neurodegenerative diseases
10.1016/j.jpba.2021.114553 · 2022 · External reference
10.1016/s1672-0229(07)60018-7
10.1016/s1672-0229(07)60018-7 · External reference
Proteomics: challenges, techniques and possibilities to overcome biological sample complexity
2009 · External reference
10.4331/wjbc.v12.i5.57
10.4331/wjbc.v12.i5.57 · External reference
Challenges and solutions in proteomics
10.2174/138920207780076910 · 2007 · External reference
10.3892/br.2020.1300
10.3892/br.2020.1300 · External reference
10.1152/physrev.00030.2001
10.1152/physrev.00030.2001 · External reference
Annexin A12–26 treatment improves skin heterologous transplantation by modulating inflammation and angiogenesis processes
10.3389/fphar.2018.01015 · 2018 · External reference
Annexin A1 N-terminal derived peptide Ac2-26 stimulates fibroblast migration in high glucose conditions
10.1371/journal.pone.0045639 · 2012 · External reference
The epidermal barrier function is dependent on the serine protease CAP1/Prss8
10.1083/jcb.200501038 · 2005 · External reference
Kallikreins: essential epidermal messengers for regulation of the skin microenvironment during homeostasis, repair and disease
2020 · External reference
Unresolved reference
External reference
An overview of the immunological defenses in fish skin
10.5402/2012/853470 · 2012 · External reference
Proteomic approach to skin regeneration in a marine teleost: modulation by oestradiol-17β
10.1007/s10126-013-9513-4 · 2013 · External reference
Wound management in teleost fish: biology of the healing process, evaluation, and treatment
10.1016/j.cvex.2003.08.007 · 2004 · External reference
Duration of scar maturation: retrospective analyses of 361 hypertrophic scars over 5 years
10.1097/01.asw.0000547415.38888.c4 · 2019 · External reference
Unresolved reference
External reference
10.1038/jid.2012.503
10.1038/jid.2012.503 · External reference
The Zebrafish model in dermatology: an update for clinicians
2022 · External reference
Gapped BLAST and PSI-BLAST: a new generation of protein database search programs
10.1093/nar/25.17.3389 · 1997 · External reference
UniProt: the universal protein knowledgebase in 2021
2021 · External reference
New and continuing developments at PROSITE
2013 · External reference
10.3390/ijms19072064
10.3390/ijms19072064 · External reference
Accessing NCBI data using the NCBI Sequence Viewer and Genome Data Viewer (GDV)
10.1101/gr.266932.120 · 2021 · External reference
Primer3 on the WWW for general users and for biologist programmers
2000 · External reference
PCR primer design
2009 · External reference
10.2353/jmoldx.2010.090035
10.2353/jmoldx.2010.090035 · External reference
Primer-BLAST: a tool to design target-specific primers for polymerase chain reaction
10.1186/1471-2105-13-134 · 2012 · External reference
Polymerase chain reaction (PCR) amplification of GC-rich templates
2019 · External reference
Fed-batch fermentation of GM-CSF-producing glycoengineered Pichia pastoris under controlled specific growth rate
10.1186/1475-2859-9-93 · 2010 · External reference
Chemical Transformation of E. coli
10.1016/b978-0-12-418687-3.00028-8 · 2013 · External reference
ColabFold: making protein folding accessible to all
2022 · External reference
AlphaFold2 models indicate that protein sequence determines both structure and dynamics
2022 · External reference
DALI shines a light on remote homologs: One hundred discoveries
10.1002/pro.4519 · 2023 · External reference
Exploring protein structural dissimilarity to facilitate structure classification
10.1186/1472-6807-9-60 · 2009 · External reference
What is the probability of a chance prediction of a protein structure with an rmsd of 6 å?
10.1016/s1359-0278(98)00019-4 · 1998 · External reference
Tools for integrated sequence-structure analysis with UCSF Chimera
2006 · External reference
ConSurf: identification of functional regions in proteins by surface-mapping of phylogenetic information
10.1093/bioinformatics/19.1.163 · 2003 · External reference
ConSurf 2005: the projection of evolutionary conservation scores of residues on protein structures
10.1093/nar/gki370 · 2005 · External reference
10.1080/19420889.2019.1676139
10.1080/19420889.2019.1676139 · External reference
10.1111/j.1432-1033.1994.tb19067.x
10.1111/j.1432-1033.1994.tb19067.x · External reference
CD-HIT Suite: a web server for clustering and comparing biological sequences
10.1093/bioinformatics/btq003 · 2010 · External reference
MAFFT online service: multiple sequence alignment, interactive sequence choice and visualization
10.1093/bib/bbx108 · 2019 · External reference
The Jalview Java alignment editor
10.1093/bioinformatics/btg430 · 2004 · External reference
Rooting phylogenetic trees with distant outgroups: a case study from the commelinoid monocots
10.1093/oxfordjournals.molbev.a003999 · 2002 · External reference
IQ-TREE: a fast and effective stochastic algorithm for estimating maximum-likelihood phylogenies
10.1093/molbev/msu300 · 2015 · External reference
Unresolved reference
External reference
A critical review on serine protease: Key immune manipulator and pathology mediator
10.1016/j.aller.2016.10.011 · 2017 · External reference
Genome-wide identification, evolution, and mRNA expression of complement genes in common carp (Cyprinus carpio)
10.1016/j.fsi.2019.11.032 · 2020 · External reference
Complement genes in black rockfish (Sebastods schlegelii): genome-wide identification, evolution and their potential functions in response to Vibrio anguillarum infection
10.1016/j.fsi.2021.04.020 · 2021 · External reference
Annexins—a family of proteins with distinctive tastes for cell signaling and membrane dynamics.
2024 · External reference
Kallikreins: Essential epidermal messengers for regulation of the skin microenvironment during homeostasis, repair and disease
2020 · External reference
Molecular cloning of novel transcripts of human kallikrein-related peptidases 5, 6, 7, 8 and 9 (KLK5 – KLK9), using Next-generation sequencing
2017 · External reference
Guidelines for Sanger sequencing and molecular assay monitoring
10.1177/1040638720905833 · 2020 · External reference
Functionality of system components: conservation of protein function in protein feature space
10.1101/gr.1190803 · 2003 · External reference
10.1080/19420889.2019.1676139
10.1080/19420889.2019.1676139 · External reference
10.1515/hsz-2016-0180
10.1515/hsz-2016-0180 · External reference
Annexin A1 involved in the regulation of inflammation and cell signaling pathways
10.1016/j.cjtee.2020.02.002 · 2020 · External reference
Conservation of the three-dimensional structure in non-homologous or unrelated proteins
10.1186/1479-7364-6-10 · 2012 · External reference
Deciphering function and mechanism of calcium-binding proteins from their evolutionary imprints
10.1016/j.bbamcr.2006.09.028 · 2006 · External reference
10.1007/978-3-642-76150-8_4
10.1007/978-3-642-76150-8_4 · External reference
10.1016/j.molcel.2017.05.028
10.1016/j.molcel.2017.05.028 · External reference
The crystal structure of calcium-bound annexin Gh1 from Gossypium hirsutum and its implications for membrane binding mechanisms of plant annexins
10.1074/jbc.m801051200 · 2008 · External reference
Characterizing the binding of annexin V to a lipid bilayer using molecular dynamics simulations
10.1002/prot.24389 · 2014 · External reference
10.2210/pdb2zoc/pdb
10.2210/pdb2zoc/pdb · External reference
10.1074/jbc.m110.193086
10.1074/jbc.m110.193086 · External reference
Annexin A4 and A6 induce membrane curvature and constriction during cell membrane repair
2017 · External reference
10.1080/09168451.2019.1695576
10.1080/09168451.2019.1695576 · External reference
10.1042/bj20070255
10.1042/bj20070255 · External reference
Subversion of complement by hematophagous parasites
10.1016/j.dci.2008.07.010 · 2009 · External reference
Molecular markers of serine protease evolution
10.1093/emboj/20.12.3036 · 2001 · External reference
10.1529/biophysj.104.057158
10.1529/biophysj.104.057158 · External reference
10.1371/journal.pone.0013781
10.1371/journal.pone.0013781 · External reference
10.1016/j.jmb.2007.08.042
10.1016/j.jmb.2007.08.042 · External reference
10.3390/ijms22041658
10.3390/ijms22041658 · External reference
Kallikreins on steroids: structure, function, and hormonal regulation of prostate-specific antigen and the extended kallikrein locus
10.1210/er.2009-0034 · 2010 · External reference
10.1074/jbc.272.48.29987
10.1074/jbc.272.48.29987 · External reference
Overlapping specificity of duplicated human pancreatic elastase 3 isoforms and archetypal porcine elastase 1 Provides Clues to evolution of digestive enzymes
10.1074/jbc.m116.770560 · 2017 · External reference
cDNA cloning and phylogenetic analysis of pancreatic serine proteases from Japanese flounder, Paralichthys olivaceus
10.1016/s1096-4959(01)00487-0 · 2002 · External reference
Converting trypsin to chymotrypsin: structural determinants of S1‘ Specificity†
10.1021/bi970937l · 1997 · External reference
10.1021/bi900496m
10.1021/bi900496m · External reference
Effective enzymatic debridement of burn wounds depends on the denaturation status of collagen
10.1111/wrr.12827 · 2020 · External reference
Substrates incorporating unnatural amino acids are separately detectable for chymotrypsin and subtilisin with similar specificity
10.1016/j.rechem.2023.101217 · 2023 · External reference
Arginine substitution by alanine at the P1 position increases the selectivity of CmPI-II, a non-classical Kazal inhibitor
2021 · External reference
Neutrophils and wound repair: positive actions and negative reactions
10.1089/wound.2012.0383 · 2013 · External reference
Bromelain-loaded chitosan nanofibers prepared by electrospinning method for burn wound healing in animal models
10.1016/j.lfs.2019.05.028 · 2019 · External reference