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References from Plasticity of BioPhi-driven humanness optimization in ScFv-CD99 binding affinity validated through AlphaFold, HADDOCK, and MD simulations. Local targets link to admitted publications; unresolved targets remain external evidence.
Next-generation therapeutic antibodies for cancer treatment: advancements, applications, and challenges
2024 · External reference
Targeted immunotherapy for autoimmune disease
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10.1093/intimm/dxv063 · External reference
10.1111/j.1476-5381.2009.00190.x
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Antibody humanization by CDR grafting
2004 · External reference
Trastuzumab mechanism of action; 20 years of research to unravel a dilemma
10.3390/cancers13143540 · 2021 · External reference
Tocilizumab for the treatment of rheumatoid arthritis and other systemic autoimmune diseases: current perspectives and future directions
10.1155/2012/946048 · 2012 · External reference
Preliminary report of a phase I study of combination chemotherapy and humanized A33 antibody immunotherapy in patients with advanced colorectal cancer
2003 · External reference
Humanized 3F8 anti-GD2 monoclonal antibody dosing with granulocyte-macrophage colony-stimulating factor in patients with resistant neuroblastoma: a phase 1 clinical trial
10.1001/jamaoncol.2018.4005 · 2018 · External reference
Designing stable humanized antibodies
10.1038/s41551-023-01168-1 · 2024 · External reference
Prospects for the computational humanization of antibodies and nanobodies
10.3389/fimmu.2024.1399438 · 2024 · External reference
10.1186/1472-6750-13-55
10.1186/1472-6750-13-55 · External reference
Humanization of antibodies using a machine learning approach on large-scale repertoire data
10.1093/bioinformatics/btab434 · 2021 · External reference
BioPhi: a platform for antibody design, humanization, and humanness evaluation based on natural antibody repertoires and deep learning
10.1080/19420862.2021.2020203 · 2022 · External reference
10.1093/intimm/dxx077
10.1093/intimm/dxx077 · External reference
10.1371/journal.pone.0080636
10.1371/journal.pone.0080636 · External reference
10.1002/jmr.2527
10.1002/jmr.2527 · External reference
Engineering affinity of humanized ScFv targeting CD147 antibody: a combined approach of mCSM-AB2 and molecular dynamics simulations
10.1016/j.jmgm.2024.108884 · 2024 · External reference
10.1084/jem.20150354
10.1084/jem.20150354 · External reference
10.1007/s12079-017-0445-z
10.1007/s12079-017-0445-z · External reference
Robust diagnosis of Ewing sarcoma by immunohistochemical detection of super-enhancer-driven EWSR1-ETS targets
10.18632/oncotarget.20098 · 2018 · External reference
10.1158/1078-0432.ccr-14-0492
10.1158/1078-0432.ccr-14-0492 · External reference
10.1016/j.jmb.2021.167402
10.1016/j.jmb.2021.167402 · External reference
Production, characterization, and functional analysis of newly established CD99 monoclonal antibodies MT99/1 and MT99/2
10.1089/hyb.2007.0504 · 2007 · External reference
A genetically engineered murine/human chimeric antibody retains specificity for human tumor-associated antigen
10.4049/jimmunol.137.3.1066 · 1986 · External reference
10.3390/biom14111422
10.3390/biom14111422 · External reference
10.1002/pro.4865
10.1002/pro.4865 · External reference
10.3389/fimmu.2023.1275999
10.3389/fimmu.2023.1275999 · External reference
10.1038/s41586-021-03819-2
10.1038/s41586-021-03819-2 · External reference
10.1038/s41586-024-07487-w
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10.1038/s41596-024-01011-0
10.1038/s41596-024-01011-0 · External reference
10.1093/nar/gkad1011
10.1093/nar/gkad1011 · External reference
RCSB protein data bank: exploring protein 3D similarities via comprehensive structural alignments
10.1093/bioinformatics/btae370 · 2024 · External reference
PRODIGY: a web server for predicting the binding affinity of protein–protein complexes
10.1093/bioinformatics/btw514 · 2016 · External reference
Contacts-based prediction of binding affinity in protein–protein complexes
10.7554/elife.07454 · 2015 · External reference
Prediction of immunogenicity for humanized and full human therapeutic antibodies
10.1371/journal.pone.0238150 · 2020 · External reference
10.1021/acs.jcim.3c01153
10.1021/acs.jcim.3c01153 · External reference
10.1021/acs.jctc.9b00591
10.1021/acs.jctc.9b00591 · External reference
10.1021/ct200909j
10.1021/ct200909j · External reference
10.1021/ct400314y
10.1021/ct400314y · External reference
10.1021/ct400341p
10.1021/ct400341p · External reference
10.1021/acs.chemrev.9b00055
10.1021/acs.chemrev.9b00055 · External reference
10.1007/978-1-62703-658-0_11
10.1007/978-1-62703-658-0_11 · External reference
PCA versus LDA
10.1109/34.908974 · 2001 · External reference
10.1371/journal.pone.0277745
10.1371/journal.pone.0277745 · External reference
10.1371/journal.pone.0276786
10.1371/journal.pone.0276786 · External reference
10.1002/prot.26237
10.1002/prot.26237 · External reference
10.2210/pdb8s89/pdb
10.2210/pdb8s89/pdb · External reference
lDDT: a local superposition-free score for comparing protein structures and models using distance difference tests
10.1093/bioinformatics/btt473 · 2013 · External reference
10.1038/356083a0
10.1038/356083a0 · External reference
Probing the "fingers" domain binding pocket of Hepatitis C virus NS5B RdRp and D559G resistance mutation via molecular docking, molecular dynamics simulation and binding free energy calculations
10.1080/07391102.2018.1491419 · 2019 · External reference
Molecular mechanism and energy basis of conformational diversity of antibody SPE7 revealed by molecular dynamics simulation and principal component analysis
10.1038/srep36900 · 2016 · External reference
10.1002/jcc.21303
10.1002/jcc.21303 · External reference
10.1016/j.jmb.2007.05.022
10.1016/j.jmb.2007.05.022 · External reference
10.1073/pnas.2008209117
10.1073/pnas.2008209117 · External reference
Mutational scanning of spike RBD protein for enhanced ACE2 affinity emerging Southeast Asia in the late transmission phase
10.1038/s41598-022-09999-9 · 2022 · External reference
10.1093/nar/gkp318
10.1093/nar/gkp318 · External reference
Evaluation of alphafold-multimer prediction on multi-chain protein complexes
2023 · External reference
10.1038/s41467-022-28865-w
10.1038/s41467-022-28865-w · External reference
10.1038/s41594-022-00910-8
10.1038/s41594-022-00910-8 · External reference
Proline-rich sequence recognition domains (PRD): ligands, function and inhibition
10.1007/978-3-540-72843-6_17 · 2008 · External reference
10.1016/j.jmb.2016.08.019
10.1016/j.jmb.2016.08.019 · External reference
Unresolved reference
External reference
10.18632/oncotarget.26002
10.18632/oncotarget.26002 · External reference
10.1016/0022-2836(92)91010-m
10.1016/0022-2836(92)91010-m · External reference
10.1016/s0161-5890(03)00022-1
10.1016/s0161-5890(03)00022-1 · External reference
