Research graph
References from Analysis of Fbox substrate adapter proteins using ProteoSync , a program for projection of evolutionary conservation onto protein atomic coordinates. Local targets link to admitted publications; unresolved targets remain external evidence.
Unresolved reference
External reference
10.1016/s0022-2836(05)80360-2
10.1016/s0022-2836(05)80360-2 · External reference
10.1093/bioinformatics/btm076
10.1093/bioinformatics/btm076 · External reference
Two WXXF-based motifs in NECAPs define the specificity of accessory protein binding to AP-1 and AP-2
10.1038/sj.emboj.7600378 · 2004 · External reference
10.1093/nar/gkw408
10.1093/nar/gkw408 · External reference
10.1093/nar/gkh131
10.1093/nar/gkh131 · External reference
10.1093/nar/gkae1010
10.1093/nar/gkae1010 · External reference
10.1093/nar/gkab1112
10.1093/nar/gkab1112 · External reference
10.1093/nar/gkae1071
10.1093/nar/gkae1071 · External reference
10.1016/j.molcel.2007.02.022
10.1016/j.molcel.2007.02.022 · External reference
10.1093/nar/22.22.4673
10.1093/nar/22.22.4673 · External reference
Unresolved reference
External reference
10.1002/bip.360221211
10.1002/bip.360221211 · External reference
10.1038/s41586-021-03819-2
10.1038/s41586-021-03819-2 · External reference
The F-box protein family
10.1186/gb-2000-1-5-reviews3002 · 2000 · External reference
10.1016/j.biocel.2016.02.005
10.1016/j.biocel.2016.02.005 · External reference
The highs and lows of FBXW7: new insights into substrate affinity in disease and development
10.3390/cells12172141 · 2023 · External reference
10.1038/35107009
10.1038/35107009 · External reference
Human F-box protein hCdc4 targets cyclin e for proteolysis and is mutated in a breast cancer cell line
10.1038/35095076 · 2001 · External reference
10.1126/science.1092880
10.1126/science.1092880 · External reference
10.1046/j.1471-4159.2002.01105.x
10.1046/j.1471-4159.2002.01105.x · External reference
10.1016/s0092-8674(03)00034-5
10.1016/s0092-8674(03)00034-5 · External reference
10.1126/science.1176326
10.1126/science.1176326 · External reference
10.1126/science.1176333
10.1126/science.1176333 · External reference
10.1016/j.molcel.2020.02.011
10.1016/j.molcel.2020.02.011 · External reference
10.1074/jbc.m111.308684
10.1074/jbc.m111.308684 · External reference
FBXW2 inhibits prostate cancer proliferation and metastasis via promoting EGFR ubiquitylation and degradation
10.1007/s00018-022-04320-3 · 2022 · External reference
FBXW2 suppresses breast tumorigenesis by targeting AKT-Moesin-SKP2 axis
10.1038/s41419-023-06127-x · 2023 · External reference
The beta-TrCP-FBXW2-SKP2 axis regulates lung cancer cell growth with FBXW2 acting as a tumour suppressor
10.1038/ncomms14002 · 2017 · External reference
FBXW2 suppresses migration and invasion of lung cancer cells via promoting beta-catenin ubiquitylation and degradation
10.1038/s41467-019-09289-5 · 2019 · External reference
10.1074/jbc.m413986200
10.1074/jbc.m413986200 · External reference
Structure of a beta-TrCP1-Skp1-beta-catenin complex: destruction motif binding and lysine specificity of the SCF(beta-TrCP1) ubiquitin ligase
2003 · External reference
A mitochondrial SCF-FBXL4 ubiquitin E3 ligase complex degrades BNIP3 and NIX to restrain mitophagy and prevent mitochondrial disease
10.15252/embj.2022113033 · 2023 · External reference
FBXL4 suppresses mitophagy by restricting the accumulation of NIX and BNIP3 mitophagy receptors
10.15252/embj.2022112767 · 2023 · External reference
10.1093/bioinformatics/18.suppl_1.s71
10.1093/bioinformatics/18.suppl_1.s71 · External reference
10.1093/nar/gky427
10.1093/nar/gky427 · External reference
10.1038/s41580-023-00673-0
10.1038/s41580-023-00673-0 · External reference
10.1016/j.bpj.2016.11.3200
10.1016/j.bpj.2016.11.3200 · External reference
