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References from Mathematical strategies for predicting resistant subpopulations from scRNAseq data of a PANC-1 3D tissue model: Insight into gemcitabine resistance and TGFB1-induced invasion and EMT. Local targets link to admitted publications; unresolved targets remain external evidence.
10.1016/j.pan.2014.10.001
10.1016/j.pan.2014.10.001 · External reference
Pathologic classification of “pancreatic cancers”: current concepts and challenges
10.21037/cco.2017.12.01 · 2017 · External reference
Unresolved reference
External reference
Survival of pancreatic cancer patients is negatively correlated with age at diagnosis: a population-based retrospective study
10.1038/s41598-020-64068-3 · 2020 · External reference
Pancreatic cancer
10.1016/j.mpsur.2024.10.004 · 2025 · External reference
10.1001/jamaoncol.2024.1930
10.1001/jamaoncol.2024.1930 · External reference
10.1053/j.gastro.2019.01.259
10.1053/j.gastro.2019.01.259 · External reference
Pancreatic cancer chemoresistance to gemcitabine
10.3390/cancers9110157 · 2017 · External reference
10.1056/nejmoa1011923
10.1056/nejmoa1011923 · External reference
10.1016/s1470-2045(16)00172-8
10.1016/s1470-2045(16)00172-8 · External reference
2D and 3D cell cultures – a comparison of different types of cancer cell cultures
2018 · External reference
10.1016/j.addr.2021.04.018
10.1016/j.addr.2021.04.018 · External reference
10.3892/ijo.2016.3513
10.3892/ijo.2016.3513 · External reference
Unresolved reference
2012 · External reference
Unresolved reference
2015 · External reference
Stroma-Targeting therapy in pancreatic cancer: one coin with two sides?
10.3389/fonc.2020.576399 · 2020 · External reference
Bioengineered 3D models of human pancreatic cancer recapitulate in vivo tumour biology
10.1038/s41467-021-25921-9 · 2021 · External reference
10.1016/j.trsl.2022.08.015
10.1016/j.trsl.2022.08.015 · External reference
10.3390/cancers14092176
10.3390/cancers14092176 · External reference
10.1002/1878-0261.12323
10.1002/1878-0261.12323 · External reference
Connecting cancer pathways to tumor engines: a stratification tool for colorectal cancer combining human in vitro tissue models with boolean in silico models
10.3390/cancers12010028 · 2020 · External reference
Phenotype and genotype of pancreatic cancer cell lines
2010 · External reference
10.1016/j.csbj.2025.09.028
10.1016/j.csbj.2025.09.028 · External reference
10.1016/j.csbj.2023.06.002 · Admitted local publication
10.1371/journal.pone.0302045 · 2024 · Admitted local publication
10.1016/j.csbj.2025.07.047
10.1016/j.csbj.2025.07.047 · External reference
10.1186/s13073-022-01075-1
10.1186/s13073-022-01075-1 · External reference
Engineered Liver-Like tissue on a capillarized matrix for applied research
10.1089/ten.2006.0388 · 2007 · External reference
10.1016/j.mtla.2025.102440
10.1016/j.mtla.2025.102440 · External reference
Unresolved reference
External reference
10.1038/nbt.3192
10.1038/nbt.3192 · External reference
10.1038/nbt.4096
10.1038/nbt.4096 · External reference
10.1016/j.cell.2019.05.031
10.1016/j.cell.2019.05.031 · External reference
10.1016/j.cell.2021.04.048
10.1016/j.cell.2021.04.048 · External reference
10.1038/s41587-023-01767-y
10.1038/s41587-023-01767-y · External reference
10.1016/j.cels.2019.03.003
10.1016/j.cels.2019.03.003 · External reference
10.1186/s13059-014-0550-8
10.1186/s13059-014-0550-8 · External reference
10.1093/bioinformatics/bty895
10.1093/bioinformatics/bty895 · External reference
Unresolved reference
External reference
Unresolved reference
External reference
Clusterprofiler: an r package for comparing biological themes among gene clusters
10.1089/omi.2011.0118 · 2012 · External reference
Clusterprofiler 4.0: a universal enrichment tool for interpreting omics data
2021 · External reference
Unresolved reference
External reference
10.32614/cran.package.babelgene
10.32614/cran.package.babelgene · External reference
10.1186/s13059-017-1382-0
10.1186/s13059-017-1382-0 · External reference
10.1038/s41587-023-01733-8
10.1038/s41587-023-01733-8 · External reference
GSEApy: a comprehensive package for performing gene set enrichment analysis in python
2022 · External reference
10.1016/j.cels.2015.12.004
10.1016/j.cels.2015.12.004 · External reference
10.1038/75556
10.1038/75556 · External reference
10.1093/nar/gkp896
10.1093/nar/gkp896 · External reference
10.1093/nar/30.1.42
10.1093/nar/30.1.42 · External reference
10.1093/nar/gkn760
10.1093/nar/gkn760 · External reference
10.1093/nar/gky1131
10.1093/nar/gky1131 · External reference
10.1093/nar/gkac1000
10.1093/nar/gkac1000 · External reference
Analysis of a large cohort of pancreatic cancer transcriptomic profiles to reveal the strongest prognostic factors
10.1111/cts.13563 · 2023 · External reference
10.1093/nar/30.1.207
10.1093/nar/30.1.207 · External reference
Integrated analysis of public datasets for the discovery and validation of survival-associated genes in solid tumors
2024 · External reference
10.1111/bph.16257
10.1111/bph.16257 · External reference
10.1038/s41388-020-1289-1
10.1038/s41388-020-1289-1 · External reference
Single-Cell transcriptomics identifies a unique entity and signature markers of Transit-Amplifying cells in human corneal limbus
2021 · External reference
CDK1 inhibitor controls G2/M phase transition and reverses DNA damage sensitivity
10.1016/j.bbrc.2021.02.117 · 2021 · External reference
Enhanced morphological and functional differences of pancreatic cancer with epithelial or mesenchymal characteristics in 3D culture
10.1038/s41598-019-47416-w · 2019 · External reference
TGFβ signaling increases net acid extrusion, proliferation and invasion in Panc-1 pancreatic cancer cells: SMAD4 dependence and link to Merlin/NF2 signaling
10.3389/fonc.2020.00687 · 2020 · External reference
10.3390/cancers13246204
10.3390/cancers13246204 · External reference
10.1002/ijc.32247
10.1002/ijc.32247 · External reference
10.1007/s12029-018-00195-5
10.1007/s12029-018-00195-5 · External reference
10.1007/s11605-021-05087-x
10.1007/s11605-021-05087-x · External reference
Unresolved reference
External reference
Spatial tumor immune heterogeneity facilitates subtype co-existence and therapy response in pancreatic cancer
10.1038/s41467-024-55330-7 · 2025 · External reference
Inhibiting tumor necrosis factor-alpha diminishes desmoplasia and inflammation to overcome chemoresistance in pancreatic ductal adenocarcinoma
10.18632/oncotarget.13212 · 2016 · External reference
10.1074/jbc.m112.428920
10.1074/jbc.m112.428920 · External reference
Transfection of keratin 18 gene in human breast cancer cells causes induction of adhesion proteins and dramatic regression of malignancy in vitro and in vivo
10.1158/1541-7786.mcr-04-0117 · 2005 · External reference
Downregulation of cytokeratin 18 is associated with paclitaxel‑resistance and tumor aggressiveness in prostate cancer
10.3892/ijo.2016.3396 · 2016 · External reference
10.3390/cells11162583
10.3390/cells11162583 · External reference
Identification of pancreatic cancer invasion-related proteins by proteomic analysis
10.1186/1477-5956-7-3 · 2009 · External reference
Expression of keratins 8, 18, and 19 in epithelia of atrophic oral lichen planus
10.1111/eos.12666 · 2020 · External reference
PMEPA1 stimulates the proliferation, colony formation of pancreatic cancer cells via the MAPK signaling pathway
10.1016/j.amjms.2021.04.002 · 2021 · External reference
PMEPA1 interference activates PTEN/PI3K/AKT, thereby inhibiting the proliferation, invasion and migration of pancreatic cancer cells and enhancing the sensitivity to gemcitabine and cisplatin
10.1002/ddr.21844 · 2022 · External reference
The identification of liver metastasis- and prognosis-associated genes in pancreatic ductal adenocarcinoma
10.1186/s12885-022-09577-2 · 2022 · External reference
Inhibition of TGF-β-receptor signaling augments the antitumor function of ROR1-specific CAR T-cells against triple-negative breast cancer
10.1136/jitc-2020-000676 · 2020 · External reference
ROR1-CAR t cells are effective against lung and breast cancer in advanced microphysiologic 3D tumor models
10.1172/jci.insight.126345 · 2019 · External reference
Modular micro-physiological human tumor/tissue models based on decellularized tissue for improved preclinical testing
2021 · External reference
A combined 3D tissue engineered in Vitro/In silico lung tumor model for predicting drug effectiveness in specific mutational backgrounds
2016 · External reference
Effect of gemcitabine on the expression of apoptosis-related genes in human pancreatic cancer cells
10.3748/wjg.v12.i10.1597 · 2006 · External reference
10.1126/sciadv.adu2339
10.1126/sciadv.adu2339 · External reference
10.1186/1472-6750-3-11 · 2003 · Admitted local publication
BIRC5 is a target for molecular imaging and detection of human pancreatic cancer
10.1016/j.canlet.2019.04.036 · 2019 · External reference
Insights into gemcitabine resistance in pancreatic cancer: association with metabolic reprogramming and TP53 pathogenicity in patient derived xenografts
10.1186/s12967-024-05528-6 · 2024 · External reference
Calcium channel blockers potentiate gemcitabine chemotherapy in pancreatic cancer
10.1073/pnas.2200143119 · 2022 · External reference
10.3390/cancers14092057
10.3390/cancers14092057 · External reference
Molecular profiling and specific targeting of gemcitabine-resistant subclones in heterogeneous pancreatic cancer cell populations
10.3389/fonc.2023.1230382 · 2023 · External reference
Post-translational modification of CDK1–STAT3 signaling by fisetin suppresses pancreatic cancer stem cell properties
10.1186/s13578-023-01118-z · 2023 · External reference
Cyclin dependent Kinase-1 (CDK-1) inhibition as a novel therapeutic strategy against pancreatic ductal adenocarcinoma (PDAC)
10.3390/cancers13174389 · 2021 · External reference
H2A.Z overexpression suppresses senescence and chemosensitivity in pancreatic ductal adenocarcinoma
10.1038/s41388-021-01664-1 · 2021 · External reference
10.1016/j.csbj.2024.04.010 · Admitted local publication
Adaptive sampling methods facilitate the determination of reliable dataset sizes for evidence-based modeling
10.3389/fbinf.2025.1528515 · 2025 · External reference
