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References from LC-MS/MS identifies elevated imidazole propionate and gut-derived metabolite alterations in peritoneal dialysis patients. Local targets link to admitted publications; unresolved targets remain external evidence.
Unresolved reference
External reference
Peritoneal dialysis
10.1056/nejmra2100152 · 2021 · External reference
The "PD First" policy in Thailand: three-years experiences (2008-2011)
2011 · External reference
Epidemiology of peritoneal dialysis outcomes
10.1038/s41581-022-00623-7 · 2022 · External reference
10.1053/j.jrn.2021.09.007
10.1053/j.jrn.2021.09.007 · External reference
Altered gut microbiota and gut-derived p-cresyl sulfate serum levels in peritoneal dialysis patients
10.3389/fcimb.2022.639624 · 2022 · External reference
The cardiovascular effect of the uremic solute indole-3 acetic acid
10.1681/asn.2013121283 · 2015 · External reference
Uremic toxins, oxidative stress, and renal fibrosis: an interwined complex
10.1053/j.jrn.2014.10.010 · 2015 · External reference
10.1038/ki.2012.345
10.1038/ki.2012.345 · External reference
10.1681/asn.2013080905
10.1681/asn.2013080905 · External reference
Gut microbiota generation of protein-bound uremic toxins and related metabolites is not altered at different stages of chronic kidney disease
10.1016/j.kint.2020.01.028 · 2020 · External reference
10.1136/gutjnl-2019-319766
10.1136/gutjnl-2019-319766 · External reference
Continuous reduction of protein-bound uraemic toxins with improved oxidative stress by using the oral charcoal adsorbent AST-120 in haemodialysis patients
10.1038/srep14381 · 2015 · External reference
Adsorption of protein-bound uremic toxins through direct hemoperfusion with hexadecyl-immobilized cellulose beads in patients undergoing hemodialysis
10.1111/aor.12961 · 2018 · External reference
10.1038/s41467-019-09735-4
10.1038/s41467-019-09735-4 · External reference
10.1016/j.cell.2018.09.055
10.1016/j.cell.2018.09.055 · External reference
Imidazole propionate is increased in diabetes and associated with dietary patterns and altered microbial ecology
10.1038/s41467-020-19589-w · 2020 · External reference
Microbially produced imidazole propionate is associated with heart failure and mortality
10.1016/j.jchf.2023.03.008 · 2023 · External reference
Joint association of TyG index and LDL-C with all-cause and cardiovascular mortality among patients with cardio-renal-metabolic disease
10.1038/s41598-025-87416-7 · 2025 · External reference
The public health impact of hypertension and diabetes: a powerful tag team for the development of chronic kidney disease
10.1038/s41440-022-01114-9 · 2023 · External reference
Type 2 diabetes mellitus in adults: pathogenesis, prevention and therapy
10.1038/s41392-024-01951-9 · 2024 · External reference
The interplay between diabetes, cardiovascular disease, and kidney disease
10.2337/db20211-13 · 2021 · External reference
10.1194/jlr.r500013-jlr200
10.1194/jlr.r500013-jlr200 · External reference
10.1016/j.chom.2020.01.021
10.1016/j.chom.2020.01.021 · External reference
10.1016/j.csbj.2023.09.032 · Admitted local publication
10.1016/j.trac.2021.116375
10.1016/j.trac.2021.116375 · External reference
A targeted ultra performance liquid chromatography – Tandem mass spectrometric assay for tyrosine and metabolites in urine and plasma: application to the effects of antibiotics on mice
10.1016/j.jchromb.2020.122511 · 2021 · External reference
An LC-MS/MS analytical method for the determination of uremic toxins in patients with end-stage renal disease
10.1016/j.jpba.2020.113551 · 2020 · External reference
Combined LC-MS/MS and 16S rDNA analysis on mice under high temperature and humidity and Herb Yinchen protection mechanism
10.1038/s41598-021-84694-9 · 2021 · External reference
10.1007/s00216-016-0048-1
10.1007/s00216-016-0048-1 · External reference
Development and validation of a highly sensitive LC-MS/MS method for the analysis of bile acids in serum, plasma, and liver tissue samples
10.3390/metabo10070282 · 2020 · External reference
A simple and reliable bile acid assay in human serum by LC-MS/MS
10.1002/jcla.24279 · 2022 · External reference
Targeted LC-MS/MS profiling of bile acids in various animal tissues
10.1021/acs.jafc.1c03433 · 2021 · External reference
Determination of bile acids in biological fluids by liquid chromatography-electrospray tandem mass spectrometry
10.1016/s0022-2275(20)32342-7 · 2001 · External reference
10.1016/j.csbj.2024.05.007 · Admitted local publication
Measurement of very low-molecular weight metabolites by traveling wave ion mobility and its use in human urine samples
10.1016/j.jpha.2023.12.011 · 2024 · External reference
Rapid quantification of yeast lipid using microwave-assisted total lipid extraction and HPLC-CAD
10.1021/ac3032405 · 2013 · External reference
Unresolved reference
External reference
UPLC-ESI-MRM/MS for absolute quantification and MS/MS structural elucidation of six specialized pyranonaphthoquinone metabolites from ventilago harmandiana
10.3389/fpls.2020.602993 · 2020 · External reference
10.1007/s11306-012-0434-4
10.1007/s11306-012-0434-4 · External reference
Data processing solutions to render metabolomics more quantitative: case studies in food and clinical metabolomics using Metabox 2.0
10.1093/gigascience/giae005 · 2024 · External reference
Development and validation of LC-MS/MS method for the determination of 1-methyl-4-nitrosopiperazine (MNP) in multicomponent products with rifampicin-analytical challenges and degradation studies
10.3390/molecules28217405 · 2023 · External reference
Unresolved reference
External reference
p-Cresyl sulfate and indoxyl sulfate in hemodialysis patients
10.2215/cjn.02940509 · 2009 · External reference
10.1681/asn.2013101062
10.1681/asn.2013101062 · External reference
Rapid simultaneous determination of gut microbial phenylalanine, tyrosine, and tryptophan metabolites in rat serum, urine, and faeces using LC-MS/MS and its application to a type 2 diabetes mellitus study
10.1002/bmc.4985 · 2021 · External reference
Integrative metagenomic and metabolomic analyses reveal severity-specific signatures of gut microbiota in chronic kidney disease
10.7150/thno.41725 · 2020 · External reference
Comprehensive and semi-quantitative analysis of carboxyl-containing metabolites related to gut microbiota on chronic kidney disease using 2-picolylamine isotopic labeling LC-MS/MS
10.1038/s41598-019-55600-1 · 2019 · External reference
Predicting lupus membranous nephritis using reduced picolinic acid to tryptophan ratio as a urinary biomarker
10.1016/j.isci.2021.103355 · 2021 · External reference
High-resolution QTOF-MRM for highly accurate identification and quantification of trace levels of triterpenoids in ganoderma lucidum mycelium
10.1021/jasms.1c00175 · 2021 · External reference
Uremic toxins and their relation with oxidative stress induced in patients with CKD
10.3390/ijms22126196 · 2021 · External reference
Microbiota-derived phenylacetylglutamine associates with overall mortality and cardiovascular disease in patients with CKD
10.1681/asn.2015121302 · 2016 · External reference
10.3390/toxins14030176
10.3390/toxins14030176 · External reference
The kidney-gut-muscle axis in end-stage renal disease is similarly represented in older adults
10.3390/nu12010106 · 2019 · External reference
Association of the gut microbiome with kidney function and damage in the Hispanic Community Health Study/Study of Latinos (HCHS/SOL)
10.1080/19490976.2023.2186685 · 2023 · External reference
Diabetic kidney disease: contribution of phenyl sulfate derived from dietary tyrosine upon gut microbiota catabolism
10.3390/biom14091153 · 2024 · External reference
Phenyl sulfate, indoxyl sulfate and p-cresyl sulfate decrease glutathione level to render cells vulnerable to oxidative stress in renal tubular cells
10.1371/journal.pone.0193342 · 2018 · External reference
Protein-bound uremic toxins in hemodialysis patients measured by liquid chromatography/tandem mass spectrometry and their effects on endothelial ROS production
10.1007/s00216-012-5929-3 · 2012 · External reference
10.1016/j.bbamcr.2024.119703
10.1016/j.bbamcr.2024.119703 · External reference
Gut microbial metabolite imidazole propionate impairs endothelial cell function and promotes the development of atherosclerosis
10.1161/atvbaha.124.322346 · 2025 · External reference
Imidazole propionate is a driver and therapeutic target in atherosclerosis
10.1038/s41586-025-09263-w · 2025 · External reference
Characterization of p-hydroxy-hippuric acid as an inhibitor of Ca2+-ATPase in end-stage renal failure
10.1046/j.1523-1755.2001.59780084.x · 2001 · External reference
Slipping through the pores: hypoalbuminemia and albumin loss during hemodialysis
10.2147/ijnrd.s291348 · 2021 · External reference
Low albumin levels are associated with mortality risk in hospitalized patients
10.1016/j.amjmed.2017.07.020 · 2017 · External reference
Serum albumin and health in older people: review and meta analysis
10.1016/j.maturitas.2015.02.009 · 2015 · External reference
PTH and cardiovascular risk
10.1016/j.ando.2020.02.005 · 2021 · External reference
Association of serum parathyroid hormone levels with all-cause and cause-specific mortality among U.S. adults
10.1016/j.eprac.2021.09.005 · 2022 · External reference
