Research graph
References from COVID-19 immunopathological features for the prediction and prevention of future emerging respiratory viral infections. Local targets link to admitted publications; unresolved targets remain external evidence.
Comparative overview of emerging RNA viruses: Epidemiology, pathogenesis, diagnosis and current treatment
10.1016/j.amsu.2022.103985 · 2022 · External reference
10.1016/j.bpa.2020.11.009
10.1016/j.bpa.2020.11.009 · External reference
10.3390/jpm12081295
10.3390/jpm12081295 · External reference
Immune responses in mildly versus critically ill COVID-19 patients
10.3389/fimmu.2023.1077236 · 2023 · External reference
Lymphocyte subset counts in COVID-19 patients: a meta-analysis
10.1002/cyto.a.24172 · 2020 · External reference
10.1038/s41591-020-0901-9
10.1038/s41591-020-0901-9 · External reference
10.1016/j.cytogfr.2020.06.001
10.1016/j.cytogfr.2020.06.001 · External reference
SARS-CoV-2 infection results in immune responses in the respiratory tract and peripheral blood that suggest mechanisms of disease severity
2022 · External reference
Acute respiratory distress syndrome in COVID-19: possible mechanisms and therapeutic management
10.1186/s41479-021-00092-9 · 2021 · External reference
10.1016/j.cell.2020.04.026
10.1016/j.cell.2020.04.026 · External reference
10.1080/17460441.2019.1621284
10.1080/17460441.2019.1621284 · External reference
CO-RADS: a categorical CT assessment scheme for patients suspected of having COVID-19—definition and evaluation
10.1148/radiol.2020201473 · 2020 · External reference
Sample size for detecting differentially expressed genes in microarray experiments
10.1186/1471-2164-5-87 · 2004 · External reference
A reagent for the single-step simultaneous isolation of RNA, DNA and proteins from cell and tissue samples
1993 · External reference
Titanium particles modulate lymphocyte and macrophage polarization in peri-implant gingival tissues
10.3390/ijms241411644 · 2023 · External reference
10.3390/cancers15010130
10.3390/cancers15010130 · External reference
Differential expression of NF-κB target genes in MALT lymphoma with and without chromosome translocation: insights into molecular mechanism
10.1038/leu.2010.118 · 2010 · External reference
Determining cell type abundance and expression from bulk tissues with digital cytometry
10.1038/s41587-019-0114-2 · 2019 · External reference
10.1038/nmeth.3337
10.1038/nmeth.3337 · External reference
Improved cell composition deconvolution method of bulk gene expression profiles to quantify subsets of immune cells
2019 · External reference
10.1111/imr.12283
10.1111/imr.12283 · External reference
DPP9 sequesters the C terminus of NLRP1 to repress inflammasome activation
10.1038/s41586-021-03350-4 · 2021 · External reference
IFITM3 Inhibits SARS-CoV-2 Infection and Is Associated with COVID-19 Susceptibility
10.3390/v14112553 · 2022 · External reference
Type I interferons in infectious disease
10.1038/nri3787 · 2015 · External reference
Examining Male Predominance of Severe COVID-19 Outcomes: A Systematic Review
2022 · External reference
Why do men have worse COVID-19-related outcomes? A systematic review and meta-analysis with sex adjusted for age
10.1590/1414-431x2021e11711 · 2022 · External reference
10.3390/biomedicines11061677
10.3390/biomedicines11061677 · External reference
SARS-CoV-2 variant biology: immune escape, transmission and fitness
2023 · External reference
10.1038/s41586-021-04266-9
10.1038/s41586-021-04266-9 · External reference
10.1016/j.cell.2021.06.020
10.1016/j.cell.2021.06.020 · External reference
10.1056/nejmc2015949
10.1056/nejmc2015949 · External reference
Evaluation of nasopharyngeal swab collection techniques for nucleic acid recovery and participant experience: recommendations for COVID-19 diagnostics
10.1093/ofid/ofaa488 · 2020 · External reference
Transcriptome of nasopharyngeal samples from COVID-19 patients and a comparative analysis with other SARS-CoV-2 infection models reveal disparate host responses against SARS-CoV-2
10.1186/s12967-020-02695-0 · 2021 · External reference
10.1016/j.cell.2021.07.023
10.1016/j.cell.2021.07.023 · External reference
Host expression profiling from diagnostic coronavirus disease 2019 swabs associates upper respiratory tract immune responses with radiologic lung pathology and clinical severity
10.1093/ofid/ofad190 · 2023 · External reference
Distinct host-immune response toward species related intracellular mycobacterial killing: a transcriptomic study
10.1080/21505594.2020.1726561 · 2020 · External reference
10.1146/annurev.cellbio.22.010305.104619
10.1146/annurev.cellbio.22.010305.104619 · External reference
SARS-CoV-2 evolution influences GBP and IFITM sensitivity
10.1073/pnas.2212577120 · 2023 · External reference
10.1128/jvi.01159-19
10.1128/jvi.01159-19 · External reference
10.1101/cshperspect.a016303
10.1101/cshperspect.a016303 · External reference
10.1101/gad.10.16.2067
10.1101/gad.10.16.2067 · External reference
10.4049/jimmunol.2100342
10.4049/jimmunol.2100342 · External reference
10.1111/j.1365-2567.2006.02321.x
10.1111/j.1365-2567.2006.02321.x · External reference
10.1111/j.1365-2567.2010.03255.x
10.1111/j.1365-2567.2010.03255.x · External reference
10.1111/cei.13407
10.1111/cei.13407 · External reference
Tumor accomplice: T cell exhaustion induced by chronic inflammation
10.3389/fimmu.2022.979116 · 2022 · External reference
10.1016/j.clim.2022.109177
10.1016/j.clim.2022.109177 · External reference
Depletion and Dysfunction of Dendritic Cells: Understanding SARS-CoV-2 Infection
10.3389/fimmu.2022.843342 · 2022 · External reference
10.1111/j.1365-2567.2009.03085.x
10.1111/j.1365-2567.2009.03085.x · External reference
10.3389/fimmu.2018.01072
10.3389/fimmu.2018.01072 · External reference
NKG2D and MICA/B shedding: a ‘tag game’ between NK cells and malignant cells
10.1002/cti2.1230 · 2020 · External reference
10.3390/cancers12123827
10.3390/cancers12123827 · External reference
“Neutrophil Extracellular Traps in Coronavirus Infection: Interaction Network Analysis,”
2020 · External reference
The Role of Interleukin-8 in Lung Inflammation and Injury: Implications for the Management of COVID-19 and Hyperinflammatory Acute Respiratory Distress Syndrome
10.3389/fphar.2021.808797 · 2022 · External reference
The IL-1β, IL-6, and TNF cytokine triad is associated with post-acute sequelae of COVID-19
2022 · External reference
Unresolved reference
External reference
Upregulated type I interferon responses in asymptomatic COVID-19 infection are associated with improved clinical outcome
10.1038/s41598-021-02489-4 · 2021 · External reference
10.1093/cid/ciaa248
10.1093/cid/ciaa248 · External reference
10.1016/j.csbj.2020.12.016 · Admitted local publication
10.1016/j.yexmp.2024.104946
10.1016/j.yexmp.2024.104946 · External reference
Tocilizumab and COVID-19: Timing of Administration and Efficacy
10.3389/fphar.2022.825749 · 2022 · External reference
Single-Cell Analysis Reveals Macrophage-Driven T Cell Dysfunction in Severe COVID-19 Patients
2020 · External reference
10.1016/j.heliyon.2024.e38688
10.1016/j.heliyon.2024.e38688 · External reference
10.1016/j.devcel.2016.02.024
10.1016/j.devcel.2016.02.024 · External reference
A translational genomics approach identifies IL10RB as the top candidate gene target for COVID-19 susceptibility
10.1038/s41525-022-00324-x · 2022 · External reference
10.1007/s10787-020-00773-9
10.1007/s10787-020-00773-9 · External reference
Genetic mechanisms of critical illness in COVID-19
10.1038/s41586-020-03065-y · 2021 · External reference
Increased risk of COVID-19 mortality rate in IFITM3 rs6598045 G allele carriers infected by SARS-CoV-2 delta variant
10.1186/s40246-022-00434-8 · 2022 · External reference
Identifying Immunological and Clinical Predictors of COVID-19 Severity and Sequelae by Mathematical Modeling
10.3389/fimmu.2022.865845 · 2022 · External reference
10.1016/j.virusres.2019.01.014
10.1016/j.virusres.2019.01.014 · External reference
PML Body Component Sp100A Is a Cytosolic Responder to IFN and Activator of Antiviral ISGs
10.1128/mbio.02044-22 · 2022 · External reference
HERC5 and the ISGylation Pathway: Critical Modulators of the Antiviral Immune Response
10.3390/v13061102 · 2021 · External reference
Interferon alpha inducible protein 6 is a negative regulator of innate immune responses by modulating RIG-I activation
10.3389/fimmu.2023.1105309 · 2023 · External reference
10.1371/journal.ppat.1004869
10.1371/journal.ppat.1004869 · External reference
Global gene expression changes in human peripheral blood after H7N9 infection
10.1016/j.gene.2014.08.062 · 2014 · External reference
Comparative Transcriptomic Analysis of Rhinovirus and Influenza Virus Infection
2020 · External reference
Bioinformatics and system biology approach to identify the influences among COVID-19, influenza, and HIV on the regulation of gene expression
2024 · External reference
Getting Started with LINCS Datasets and Tools
10.1002/cpz1.487 · 2022 · External reference
The COVID-19 Drug and Gene Set Library
10.1016/j.patter.2020.100090 · 2020 · External reference
10.1007/s00439-020-02167-x
10.1007/s00439-020-02167-x · External reference
Trans-ancestry GWAS identifies 59 loci and improves risk prediction and fine-mapping for kidney stone disease
10.1038/s41467-025-58782-7 · 2025 · External reference
Pollutants, microbiota and immune system: frenemies within the gut
10.3389/fpubh.2024.1285186 · 2024 · External reference
10.3390/microorganisms10071457
10.3390/microorganisms10071457 · External reference
10.1016/j.xgen.2023.100469
10.1016/j.xgen.2023.100469 · External reference