Contact and support
Need help, have a question, or want to contact the ResearchHub team?
© 2026 ResearchHub. Built for responsible scholarly connection.
Research graph
References from Oxidative stress-driven transcriptomic remodeling in human astrocytes reveals network signatures associated with neurodegenerative and cardiovascular processes. Local targets link to admitted publications; unresolved targets remain external evidence.
10.1152/physrev.00042.2016
10.1152/physrev.00042.2016 · External reference
Ménage à Trois: the role of neurotransmitters in the energy metabolism of astrocytes, glutamatergic, and GABAergic neurons
10.1038/jcbfm.2012.31 · 2012 · External reference
10.7554/elife.32237
10.7554/elife.32237 · External reference
Astrocyte-mediated switch in spike timing-dependent plasticity during hippocampal development
10.1038/s41467-020-18024-4 · 2020 · External reference
10.1002/glia.23250
10.1002/glia.23250 · External reference
10.3109/09687688.2014.937468
10.3109/09687688.2014.937468 · External reference
10.3390/antiox13101208
10.3390/antiox13101208 · External reference
Astrocytic calcium and cAMP in Neurodegenerative diseases
10.3389/fncel.2022.889939 · 2022 · External reference
The role of astrocytes in oxidative stress of central nervous system: a mixed blessing
10.1111/cpr.12781 · 2020 · External reference
The impact of cerebrovascular aging on vascular cognitive impairment and dementia
10.1016/j.arr.2016.09.007 · 2017 · External reference
Epidemiology of heart failure: a contemporary perspective
10.1161/circresaha.121.318172 · 2021 · External reference
Ng, & Turek. Heart disease as a risk factor for dementia
2013 · External reference
The interaction and pathogenesis between cognitive impairment and common cardiovascular diseases in the elderly
2022 · External reference
Cardiac contributions to brain health: a scientific statement from the american heart association
10.1161/str.0000000000000476 · 2024 · External reference
Vascular disease and risk factors are associated with cognitive decline in the Alzheimer disease spectrum
10.1097/wad.0000000000000043 · 2015 · External reference
10.3233/jad-190654
10.3233/jad-190654 · External reference
10.1016/j.nbd.2025.106877
10.1016/j.nbd.2025.106877 · External reference
10.3389/fnmol.2017.00427
10.3389/fnmol.2017.00427 · External reference
Astrocytes in Neurodegenerative disease: Table 1
10.1101/cshperspect.a020628 · 2015 · External reference
Neurovascular dysfunction in vascular dementia, Alzheimer’s and atherosclerosis
10.1186/s12868-018-0465-5 · 2018 · External reference
Metabolic perspective of astrocyte dysfunction in Alzheimer’s disease and type 2 diabetes brains
10.1016/j.biopha.2022.114206 · 2023 · External reference
10.1016/j.cell.2022.11.001
10.1016/j.cell.2022.11.001 · External reference
Biana: a software framework for compiling biological interactions and analyzing networks
10.1186/1471-2105-11-56 · 2010 · External reference
The IntAct database: efficient access to fine-grained molecular interaction data
10.1093/nar/gkab1006 · 2022 · External reference
10.1002/pro.3978
10.1002/pro.3978 · External reference
10.1093/nar/gkw985
10.1093/nar/gkw985 · External reference
10.1093/nar/gks1147
10.1093/nar/gks1147 · External reference
UniProt: the Universal Protein Knowledgebase in 2025
2025 · External reference
10.1093/nar/gkad1025
10.1093/nar/gkad1025 · External reference
NCBI Taxonomy: a comprehensive update on curation, resources and tools
2020 · External reference
10.1038/75556
10.1038/75556 · External reference
10.1093/nar/gkw1108
10.1093/nar/gkw1108 · External reference
10.1093/nar/gkac888
10.1093/nar/gkac888 · External reference
ConsensusPathDB 2022: molecular interactions update as a resource for network biology
10.1093/nar/gkab1128 · 2022 · External reference
10.1186/gb-2007-8-5-r95
10.1186/gb-2007-8-5-r95 · External reference
10.1093/nar/gkw943
10.1093/nar/gkw943 · External reference
Exploiting protein-protein interaction networks for genome-wide disease-gene prioritization
10.1371/journal.pone.0043557 · 2012 · External reference
OMIM.org: online mendelian inheritance in man (OMIM®), an online catalog of human genes and genetic disorders
10.1093/nar/gku1205 · 2015 · External reference
Unresolved reference
2003 · External reference
Whole-proteome prediction of protein function via graph-theoretic analysis of interaction maps
10.1093/bioinformatics/bti1054 · 2005 · External reference
10.1016/j.ajhg.2008.02.013
10.1016/j.ajhg.2008.02.013 · External reference
10.1371/journal.pcbi.1000641
10.1371/journal.pcbi.1000641 · External reference
10.1371/journal.pcbi.1004120
10.1371/journal.pcbi.1004120 · External reference
10.1111/j.2517-6161.1995.tb02031.x
10.1111/j.2517-6161.1995.tb02031.x · External reference
Structural coverage of the human interactome
10.1093/bib/bbad496 · 2023 · External reference
10.1016/j.jmb.2023.168055
10.1016/j.jmb.2023.168055 · External reference
PRISM: a web server and repository for prediction of protein–protein interactions and modeling their 3D complexes
10.1093/nar/gku397 · 2014 · External reference
FoldX force field revisited, an improved version
10.1093/bioinformatics/btaf064 · 2025 · External reference
ClinVar: updates to support classifications of both germline and somatic variants
10.1093/nar/gkae1090 · 2025 · External reference
10.1016/j.febslet.2005.03.027
10.1016/j.febslet.2005.03.027 · External reference
ROMO1 overexpression protects the mitochondrial cysteinome from oxidations in aging
10.1038/s41467-025-60503-z · 2025 · External reference
Macrophage migration inhibitory factor as an emerging drug target to regulate antioxidant response element system
10.1155/2017/8584930 · 2017 · External reference
A decade of boon or burden: what has the CHIP ever done for cellular protein quality control mechanism implicated in neurodegeneration and aging?
10.3389/fnmol.2016.00093 · 2016 · External reference
10.2139/ssrn.4836768
10.2139/ssrn.4836768 · External reference
10.1016/j.jmb.2011.04.018
10.1016/j.jmb.2011.04.018 · External reference
TRMT112, a master activator of several methyltransferases modifying factors involved in RNA maturation and translation
10.3389/frnar.2025.1556979 · 2025 · External reference
The conserved Wobble uridine tRNA thiolase Ctu1–Ctu2 is required to maintain genome integrity
10.1073/pnas.0709404105 · 2008 · External reference
Structure, activation, and regulation of NOX2: at the crossroad between the innate immunity and oxidative stress-mediated pathologies
10.3390/antiox12020429 · 2023 · External reference
10.1016/j.bbamem.2006.09.019
10.1016/j.bbamem.2006.09.019 · External reference
10.3390/cells13221870
10.3390/cells13221870 · External reference
10.1074/jbc.m406906200
10.1074/jbc.m406906200 · External reference
Yif1B Is Involved in the Anterograde Traffic Pathway and the Golgi Architecture
10.1111/tra.12306 · 2015 · External reference
Structure, function, and recombinant production of EGFL7
10.1515/hsz-2023-0358 · 2024 · External reference
10.1016/j.tibs.2017.09.003
10.1016/j.tibs.2017.09.003 · External reference
10.1083/jcb.201807019
10.1083/jcb.201807019 · External reference
Specific Functions of BIG1 and BIG2 in Endomembrane Organization
10.1371/journal.pone.0009898 · 2010 · External reference
10.1042/bst20170568
10.1042/bst20170568 · External reference
10.1002/1873-3468.14749
10.1002/1873-3468.14749 · External reference
10.1016/j.pharmthera.2017.08.008
10.1016/j.pharmthera.2017.08.008 · External reference
Critical requirement of SOS1 RAS-GEF function for mitochondrial dynamics, metabolism, and redox homeostasis
10.1038/s41388-021-01886-3 · 2021 · External reference
10.1038/sj.emboj.7601668
10.1038/sj.emboj.7601668 · External reference
ATM, telomeres and aging
2003 · External reference
10.1016/j.dnarep.2010.10.012
10.1016/j.dnarep.2010.10.012 · External reference
The astrocyte-expressed integrin αvβ8 governs blood vessel sprouting in the developing retina
10.1242/dev.069153 · 2011 · External reference
Versican: a dynamic regulator of the extracellular matrix
10.1369/0022155420953922 · 2020 · External reference
10.1002/humu.23678
10.1002/humu.23678 · External reference
CAMSAPs organize an acentrosomal microtubule network from basal varicosities in radial glial cells
10.1083/jcb.202003151 · 2021 · External reference
10.1089/ars.2011.4391
10.1089/ars.2011.4391 · External reference
UBXN7 docks on neddylated cullin complexes using its UIM motif and causes HIF1α accumulation
10.1186/1741-7007-10-36 · 2012 · External reference
10.1038/nature09371
10.1038/nature09371 · External reference
10.1128/mcb.01094-10
10.1128/mcb.01094-10 · External reference
10.1038/s41380-021-01249-0
10.1038/s41380-021-01249-0 · External reference
ER-associated degradation regulates Alzheimer’s amyloid pathology and memory function by modulating γ-secretase activity
10.1038/s41467-017-01799-4 · 2017 · External reference
The unfolded protein responses in health, aging, and neurodegeneration: recent advances and future considerations
10.3389/fnmol.2022.831116 · 2022 · External reference
Nitric OXide Pathways in Neurovascular Coupling under Normal and Stress Conditions in the Brain: Strategies to Rescue Aberrant Coupling and Improve Cerebral Blood Flow
10.3389/fphys.2021.729201 · 2021 · External reference
10.1172/jci59903
10.1172/jci59903 · External reference
Insulin receptor signaling in normal and insulin-resistant states
10.1101/cshperspect.a009191 · 2014 · External reference
10.1038/nrm1837
10.1038/nrm1837 · External reference
10.1016/j.cell.2013.12.012
10.1016/j.cell.2013.12.012 · External reference
10.1038/s41569-019-0167-4
10.1038/s41569-019-0167-4 · External reference
10.1038/nature13701
10.1038/nature13701 · External reference
Inflammation and atherosclerosis: signaling pathways and therapeutic intervention
10.1038/s41392-022-00955-7 · 2022 · External reference
10.1097/moh.0000000000000361
10.1097/moh.0000000000000361 · External reference
10.1056/nejmoa1707914
10.1056/nejmoa1707914 · External reference
10.1038/ni.1863
10.1038/ni.1863 · External reference
10.1172/jci66843
10.1172/jci66843 · External reference
The mechanism of linear ubiquitination in regulating cell death and correlative diseases
10.1038/s41419-023-06183-3 · 2023 · External reference
10.1038/s12276-020-00503-9
10.1038/s12276-020-00503-9 · External reference
10.15252/embr.202154217
10.15252/embr.202154217 · External reference
Oxidative DNA damage and repair: mechanisms, mutations, and relation to diseases
10.3390/antiox12081623 · 2023 · External reference
10.1186/s13024-020-00367-7
10.1186/s13024-020-00367-7 · External reference
Human ageing genomic resources: updates on key databases in ageing research
10.1093/nar/gkad927 · 2024 · External reference
Nuclear lamins: Structure and function in mechanobiology
10.1063/5.0082656 · 2022 · External reference
Nuclear envelope dysfunction and its contribution to the aging process
10.1111/acel.13143 · 2020 · External reference
10.1038/s41594-018-0128-3
10.1038/s41594-018-0128-3 · External reference
α-actinin and filamin cooperatively enhance the stiffness of actin filament networks
10.1371/journal.pone.0004411 · 2009 · External reference
10.1038/73456
10.1038/73456 · External reference
10.1073/pnas.1505652112
10.1073/pnas.1505652112 · External reference
10.1016/j.semcdb.2011.09.001
10.1016/j.semcdb.2011.09.001 · External reference
10.1074/jbc.m109.045989
10.1074/jbc.m109.045989 · External reference
The dimeric versus monomeric status of 14-3-3ζ is controlled by phosphorylation of Ser58 at the dimer interface
10.1074/jbc.m304689200 · 2003 · External reference
10.1155/2013/564534
10.1155/2013/564534 · External reference
10.1016/j.ajhg.2014.03.003
10.1016/j.ajhg.2014.03.003 · External reference
10.1016/j.molcel.2009.05.028
10.1016/j.molcel.2009.05.028 · External reference
10.1038/s41467-022-34226-4
10.1038/s41467-022-34226-4 · External reference
10.18632/oncotarget.9821
10.18632/oncotarget.9821 · External reference
Astrocyte senescence promotes glutamate toxicity in cortical neurons
10.1371/journal.pone.0227887 · 2020 · External reference