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References from Empirical optimization of dual-sgRNA design for in vivo CRISPR/Cas9-mediated exon deletion in mice. Local targets link to admitted publications; unresolved targets remain external evidence.
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10.1016/j.cell.2014.09.014 · External reference
Gene-edited pigs are protected from porcine reproductive and respiratory syndrome virus
10.1038/nbt.3434 · 2016 · External reference
Generation of double knockout cattle via CRISPR-Cas9 ribonucleoprotein (RNP) electroporation
2023 · External reference
Exploring the importance of predicted camel NRAP exon 4 for environmental adaptation using a mouse model
2025 · External reference
PAM-flexible adenine base editing rescues hearing loss in a humanized MPZL2 mouse model harboring an East Asian founder mutation
10.1038/s41467-025-62562-8 · 2025 · External reference
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CRISPR-Cas9-mediated homology-directed repair for precise gene editing
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10.1038/s41551-024-01277-5 · External reference
Generation and propagation of high fecundity gene edited fine wool sheep by CRISPR/Cas9
2025 · External reference
In vivo CRISPR–Cas9 genome editing in mice identifies genetic modifiers of somatic CAG repeat instability in Huntington’s disease
10.1038/s41588-024-02054-5 · 2025 · External reference
Weaponizing CRISPR/Cas9 for selective elimination of cells with an aberrant genome
10.1016/j.dnarep.2025.103840 · 2025 · External reference
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Enhancing CRISPR-Cas9 gRNA efficiency prediction by data integration and deep learning
10.1038/s41467-021-23576-0 · 2021 · External reference
SpCas9 activity prediction by DeepSpCas9, a deep learning-based model with high generalization performance
2019 · External reference
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Accounting for small variations in the tracrRNA sequence improves sgRNA activity predictions for CRISPR screening
10.1038/s41467-022-33024-2 · 2022 · External reference
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Rapid and robust validation of pooled CRISPR knockout screens using CelFi
10.1038/s41598-025-96095-3 · 2025 · External reference
INDEL detection, the “Achilles heel” of precise genome editing: A survey of methods for accurate profiling of gene editing induced indels
10.1093/nar/gkaa975 · 2021 · External reference
Escaping from CRISPR–Cas-mediated knockout: the facts, mechanisms, and applications
10.1186/s11658-024-00565-x · 2024 · External reference
Cre-Controlled CRISPR mutagenesis provides fast and easy conditional gene inactivation in zebrafish
10.1038/s41467-021-21427-6 · 2021 · External reference
A benchmark comparison of CRISPRn guide-RNA design algorithms and generation of small single and dual-targeting libraries to boost screening efficiency
10.1186/s12864-025-11386-3 · 2025 · External reference
Random forest versus logistic regression: A large-scale benchmark experiment
10.1186/s12859-018-2264-5 · 2018 · External reference
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Limitations of gene editing assessments in human preimplantation embryos
2023 · External reference
Streamlined ex vivo and in vivo genome editing in mouse embryos using recombinant adenoassociated viruses
10.1038/s41467-017-02706-7 · 2018 · External reference
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10.1002/1873-3468.12707 · External reference
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10.1101/gad.339333.120 · External reference
10.1038/s41587-019-0095-1
10.1038/s41587-019-0095-1 · External reference
A CRISPR/Cas9-based system using dual-sgRNAs for efficient gene deletion in Mycobacterium abscessus
2025 · External reference
Intrinsic termination of T7 RNA polymerase mediated by either RNA or DNA
10.1002/j.1460-2075.1996.tb00854.x · 1996 · External reference
Modulating chromatin accessibility by transactivation and targeting proximal dsgRNAs enhances Cas9 editing efficiency in vivo
2019 · External reference
The Meaning and Use of the Area under a Receiver Operating Characteristic (ROC) Curve1
10.1148/radiology.143.1.7063747 · 1982 · External reference
