Research graph
References from The role of Next-Generation Sequencing in tumoral radiosensitivity prediction. Local targets link to admitted publications; unresolved targets remain external evidence.
EGFR mutations in lung cancer: correlation with clinical response to gefitinib therapy
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A decade’s perspective on DNA sequencing technology
10.1038/nature09796 · 2011 · External reference
Sequencing technologies - the next generation
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Unresolved reference
External reference
Emerging molecular networks common in ionizing radiation, immune and inflammatory responses by employing bioinformatics approaches
10.1016/j.canlet.2015.03.021 · 2015 · External reference
Genetics and genomics of radiotherapy toxicity: towards prediction
10.1186/gm268 · 2011 · External reference
Independent validation of genes and polymorphisms reported to be associated with radiation toxicity: a prospective analysis study
10.1016/s1470-2045(11)70302-3 · 2012 · External reference
A genome wide association study (GWAS) providing evidence of an association between common genetic variants and late radiotherapy toxicity
10.1016/j.radonc.2014.02.012 · 2014 · External reference
A three-stage genome-wide association study identifies a susceptibility locus for late radiotherapy toxicity at 2q24.1
10.1038/ng.3020 · 2014 · External reference
Targeted next-generation sequencing of locally advanced squamous cell carcinomas of the head and neck reveals druggable targets for improving adjuvant chemoradiation
1990 · External reference
Tumour genomic and microenvironmental heterogeneity for integrated prediction of 5-year biochemical recurrence of prostate cancer: a retrospective cohort study
10.1016/s1470-2045(14)71021-6 · 2014 · External reference
A rapid method for determining sequences in DNA by primed synthesis with DNA polymerase
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Next-generation sequencing and epigenomics research: a hammer in search of nails
10.5808/gi.2014.12.1.2 · 2014 · External reference
Mapping and quantifying mammalian transcriptomes by RNA-Seq
10.1038/nmeth.1226 · 2008 · External reference
Genome-wide mapping of in vivo protein-DNA interactions
10.1126/science.1141319 · 2007 · External reference
Next-generation sequencing of RNA and DNA isolated from paired fresh-frozen and formalin-fixed paraffin-embedded samples of human cancer and normal tissue
10.1371/journal.pone.0098187 · 2014 · External reference
Circulating tumor DNA as a non-invasive substitute to metastasis biopsy for tumor genotyping and personalized medicine in a prospective trial across all tumor types
10.1016/j.molonc.2014.12.003 · 2015 · External reference
A framework for variation discovery and genotyping using next-generation DNA sequencing data
10.1038/ng.806 · 2011 · External reference
An overview of the analysis of next generation sequencing data
10.1007/978-1-61779-400-1_16 · 2012 · External reference
Personalized radiation therapy and biomarker-driven treatment strategies: a systematic review
10.1007/s10555-013-9419-7 · 2013 · External reference
New paradigms and future challenges in radiation oncology: an update of biological targets and technology
10.1126/scitranslmed.3005148 · 2013 · External reference
Directed evolution of ionizing radiation resistance in Escherichia coli
10.1128/jb.00502-09 · 2009 · External reference
A genome-based model for adjusting radiotherapy dose (GARD): a retrospective, cohort-based study
2016 · External reference
Prediction of radiation sensitivity using a gene expression classifier
10.1158/0008-5472.can-05-0656 · 2005 · External reference
A gene expression model of intrinsic tumor radiosensitivity: prediction of response and prognosis after chemoradiation
10.1016/j.ijrobp.2009.06.014 · 2009 · External reference
Validation of a radiosensitivity molecular signature in breast cancer
10.1158/1078-0432.ccr-12-0891 · 2012 · External reference
Differences between colon cancer primaries and metastases using a molecular assay for tumor radiation sensitivity suggest implications for potential oligometastatic SBRT patient selection
10.1016/j.ijrobp.2015.01.036 · 2015 · External reference
The radiosensitivity index predicts for overall survival in glioblastoma
10.18632/oncotarget.5437 · 2015 · External reference
Integration of a radiosensitivity molecular signature into the assessment of local recurrence risk in breast cancer
10.1016/j.ijrobp.2015.06.021 · 2015 · External reference
Genomic analysis of exceptional responders to radiotherapy reveals somatic mutations in ATM
10.18632/oncotarget.14400 · 2017 · External reference
Meta-analysis of chemotherapy in head and neck cancer (MACH-NC): an update on 93 randomised trials and 17,346 patients
10.1016/j.radonc.2009.04.014 · 2009 · External reference
Exome sequencing of head and neck squamous cell carcinoma reveals inactivating mutations in NOTCH1
10.1126/science.1206923 · 2011 · External reference
The mutational landscape of head and neck squamous cell carcinoma
10.1126/science.1208130 · 2011 · External reference
Genomic alterations in head and neck squamous cell carcinoma determined by cancer gene-targeted sequencing
10.1093/annonc/mdv109 · 2015 · External reference
Integrative and comparative genomic analysis of HPV-positive and HPV-negative head and neck squamous cell carcinomas
10.1158/1078-0432.ccr-13-3310 · 2015 · External reference
Comprehensive genomic characterization of head and neck squamous cell carcinomas
10.1038/nature14129 · 2015 · External reference
Targeted next-generation sequencing identifies molecular subgroups in squamous cell carcinoma of the head and neck with distinct outcome after concurrent chemoradiation
10.1093/annonc/mdw426 · 2016 · External reference
TP53 mutations and survival in squamous-cell carcinoma of the head and neck
10.1056/nejmoa073770 · 2007 · External reference
Prognostic significance of truncating TP53 mutations in head and neck squamous cell carcinoma
10.1158/1078-0432.ccr-11-0183 · 2011 · External reference
TP53 disruptive mutations lead to head and neck cancer treatment failure through inhibition of radiation-induced senescence
10.1158/1078-0432.ccr-11-2260 · 2012 · External reference
Gain of oncogenic function of p53 mutants induces invasive phenotypes in human breast cancer cells by silencing CCN5/WISP-2
10.1158/0008-5472.can-08-0316 · 2008 · External reference
A Mutant-p53/Smad complex opposes p63 to empower TGFbeta-induced metastasis
10.1016/j.cell.2009.01.039 · 2009 · External reference
Exomics and immunogenics: bridging mutational load and immune checkpoints efficacy
10.4161/onci.27817 · 2014 · External reference
The precision-oncology illusion
10.1038/537s63a · 2016 · External reference
Feasibility of large-scale genomic testing to facilitate enrollment onto genomically matched clinical trials
10.1200/jco.2014.60.4165 · 2015 · External reference
Unresolved reference
External reference
Limits to personalized cancer medicine
10.1056/nejmsb1607705 · 2016 · External reference
