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References from Time to surgery and pathologic complete response after neoadjuvant chemoradiation in rectal cancer: A population study on 2094 patients. Local targets link to admitted publications; unresolved targets remain external evidence.
Preoperative versus postoperative chemoradiotherapy for rectal cancer
10.1056/nejmoa040694 · 2004 · External reference
EURECCA colorectal: multidisciplinary management: European consensus conference colon & rectum
10.1016/j.ejca.2013.06.048 · 2014 · External reference
Prognostic value of pathologic complete response after neoadjuvant therapy in locally advanced rectal cancer: long-term analysis of 566 ypCR patients
10.1016/j.ijrobp.2007.12.019 · 2008 · External reference
Nomograms for predicting local recurrence, distant metastases, and overall survival for patients with locally advanced rectal cancer on the basis of European randomized clinical trials
10.1200/jco.2010.33.1595 · 2011 · External reference
Correlation in rectal cancer between clinical tumor response after neoadjuvant radiotherapy and sphincter or organ preservation: 10-year results of the Lyon R 96–02 randomized trial
10.1016/j.ijrobp.2011.12.002 · 2012 · External reference
Complete pathologic response after combined modality treatment for rectal cancer and long-term survival: a meta-analysis
10.1245/s10434-011-2209-y · 2012 · External reference
Systematic review and meta-analysis of outcomes following pathological complete response to neoadjuvant chemoradiotherapy for rectal cancer
10.1002/bjs.8702 · 2012 · External reference
Long-term outcome in patients with a pathological complete response after chemoradiation for rectal cancer: a pooled analysis of individual patient data
10.1016/s1470-2045(10)70172-8 · 2016 · External reference
Effect of interval between neoadjuvant chemoradiotherapy and surgery on oncological outcome for rectal cancer: a systematic review and meta-analysis
10.1155/2016/6756859 · 2016 · External reference
Increasing the interval between neoadjuvant chemoradiotherapy and surgery in rectal cancer: a meta-analysis of published studies
10.1097/sla.0000000000000368 · 2016 · External reference
Enhanced tumorocidal effect of chemotherapy with preoperative radiotherapy for rectal cancer: preliminary results—EORTC 22921
10.1200/jco.2005.02.113 · 2005 · External reference
Preoperative radiotherapy with or without concurrent fluorouracil and leucovorin in T3–4 rectal cancers: results of FFCD 9203
10.1200/jco.2006.06.7629 · 2006 · External reference
Randomized trial of short-course radiotherapy versus long-course chemoradiation comparing rates of local recurrence in patients with T3 rectal cancer: Trans-Tasman Radiation Oncology Group trial 01.04
10.1200/jco.2012.42.9597 · 2012 · External reference
Integration of novel agents into combined-modality treatment for rectal cancer patients
10.1007/s00066-007-9000-9 · 2007 · External reference
Comparison of two neoadjuvant chemoradiotherapy regimens for locally advanced rectal cancer: results of the phase III trial ACCORD 12/0405-Prodige 2
10.1200/jco.2009.25.8376 · 2010 · External reference
Primary tumor response to preoperative chemoradiation with or without oxaliplatin in locally advanced rectal cancer: pathologic results of the STAR-01 randomized phase III trial
10.1200/jco.2010.34.4911 · 2011 · External reference
Capecitabine and oxaliplatin in the preoperative multimodality treatment of rectal cancer: surgical end points from National Surgical Adjuvant Breast and Bowel Project trial R-04
10.1200/jco.2013.53.7753 · 2014 · External reference
Preoperative chemoradiotherapy and postoperative chemotherapy with capecitabine and oxaliplatin versus capecitabine alone in locally advanced rectal cancer: disease-free survival at interim analysis
2014 · External reference
Oxaliplatin added to fluorouracil-based preoperative chemoradiotherapy and postoperative chemotherapy of locally advanced rectal cancer (the German CAO/ARO/AIO-04 study): final results of the multicentre, open-label, randomised, phase 3 trial
10.1016/s1470-2045(15)00159-x · 2015 · External reference
Impact of radiotherapy boost on pathological complete response in patients with locally advanced rectal cancer: a systematic review and meta-analysis
10.1016/j.radonc.2014.08.035 · 2014 · External reference
Radiation dose-response model for locally advanced rectal cancer after preoperative chemoradiation therapy
10.1016/j.ijrobp.2012.05.017 · 2013 · External reference
Influence of the interval between preoperative radiation therapy and surgery on downstaging and on the rate of sphincter-sparing surgery for rectal cancer: the Lyon R90–01 randomized trial
10.1200/jco.1999.17.8.2396 · 1999 · External reference
An interval >7 weeks between neoadjuvant therapy and surgery improves pathologic complete response and disease-free survival in patients with locally advanced rectal cancer
10.1245/s10434-008-9892-3 · 2008 · External reference
Predictive factors of pathologic complete response after neoadjuvant chemoradiation for rectal cancer
10.1097/sla.0b013e3181b91e63 · 2009 · External reference
Optimal time interval between neoadjuvant chemoradiotherapy and surgery for rectal cancer
10.1002/bjs.9112 · 2013 · External reference
Rate of pathologic complete response with increased interval between preoperative combined modality therapy and rectal cancer resection
10.1007/s10350-003-0062-1 · 2004 · External reference
Regression of rectal cancer with radiotherapy with or without concurrent capecitabine – optimising the timing of surgical resection
10.1016/j.clon.2008.10.011 · 2009 · External reference
Extended intervals after neoadjuvant therapy in locally advanced rectal cancer: The key to improved tumor response and potential organ preservation
10.1016/j.jamcollsurg.2015.04.010 · 2015 · External reference
Delaying surgery after neoadjuvant chemoradiotherapy for rectal cancer may reduce postoperative morbidity without compromising prognosis
10.1002/bjs.6377 · 2008 · External reference
Evaluation of safety of increased time interval between chemoradiation and resection for rectal cancer
10.1016/j.amjsurg.2006.08.061 · 2006 · External reference
Effect of adding mFOLFOX6 after neoadjuvant chemoradiation in locally advanced rectal cancer: A multicentre, phase 2 trial
10.1016/s1470-2045(15)00004-2 · 2015 · External reference
Timely tumor response analysis after preoperative chemoradiotherapy and curative surgery in locally advanced rectal cancer: A multi-institutional study for optimal surgical timing in rectal cancer
10.1016/j.radonc.2016.03.017 · 2016 · External reference
Unresolved reference
External reference
Chemoradiation therapy for rectal cancer in the distal rectum followed by organ-sparing transanal endoscopic microsurgery (CARTS study)
10.1002/bjs.9809 · 2015 · External reference
Interval between surgery and neoadjuvant chemoradiation therapy for distal rectal cancer: does delayed surgery have an impact on outcome?
10.1016/j.ijrobp.2007.11.035 · 2008 · External reference
Rectal cancer: Neoadjuvant chemoradiotherapy
10.1016/j.bpg.2016.06.004 · 2016 · External reference
Timing of rectal cancer surgery following neoadjuvant chemoradiation: how close are we to striking an equipoise?
10.2217/fon-2016-0478 · 2017 · External reference
Effect of interval (7 or 11 weeks) between neoadjuvant radiochemotherapy and surgery on complete pathologic response in rectal cancer: a multicenter, randomized, controlled trial (GRECCAR-6)
10.1200/jco.2016.67.6049 · 2016 · External reference
Results of a prospective randomised control 6 vs 12 trial: Is greater tumour downstaging observed on post treatment MRI if surgery is delayed to 12-weeks versus 6-weeks after completion of neoadjuvant chemoradiotherapy?
2016 · External reference
Pathologic response, when increased by longer interval, is a marker but not the cause of good prognosis in rectal cancer: 17-year follow-up of the Lyon R90–01 randomized trial
10.1016/j.ijrobp.2015.10.061 · 2016 · External reference
Retto-Capitolo 5
2012 · External reference