Research graph
References from P4HA1: A single-gene surrogate of hypoxia signatures in oral squamous cell carcinoma patients. Local targets link to admitted publications; unresolved targets remain external evidence.
Independent prognostic factors of 861 cases of oral squamous cell carcinoma in Korean adults
10.1016/j.oraloncology.2005.07.005 · 2006 · External reference
Differential expression profiling of head and neck squamous cell carcinoma (HNSCC)
10.1038/sj.bjc.6601373 · 2003 · External reference
Clinical relevance of the tumor microenvironment and immune escape of oral squamous cell carcinoma
10.1186/s12967-016-0828-6 · 2016 · External reference
Targeting HIF-1 for cancer therapy
10.1038/nrc1187 · 2003 · External reference
HIF-1alpha is a prognostic marker in oral squamous cell carcinomas
10.1177/172460081002500205 · 2010 · External reference
Gene expression classifier predicts for hypoxic modification of radiotherapy with nimorazole in squamous cell carcinomas of the head and neck
10.1016/j.radonc.2011.09.010 · 2012 · External reference
A 26-gene hypoxia signature predicts benefit from hypoxia-modifying therapy in laryngeal cancer but not bladder cancer
10.1158/1078-0432.ccr-13-0542 · 2013 · External reference
Generating specificity and diversity in the transcriptional response to hypoxia
10.1038/nrg2665 · 2009 · External reference
Comparative analysis of transcriptomics based hypoxia signatures in head- and neck squamous cell carcinoma
10.1016/j.radonc.2015.11.027 · 2016 · External reference
Hypoxia-inducible factor 1 (HIF-1) promotes extracellular matrix remodeling under hypoxic conditions by inducing P4HA1, P4HA2, and PLOD2 expression in fibroblasts
10.1074/jbc.m112.442939 · 2013 · External reference
Translational control of collagen prolyl 4-hydroxylase-alpha(I) gene expression under hypoxia
10.1074/jbc.m604939200 · 2006 · External reference
Hypoxia-induced gene expression results from selective mRNA partitioning to the endoplasmic reticulum
10.1093/nar/gkv167 · 2015 · External reference
The collagen prolyl hydroxylases are novel transcriptionally silenced genes in lymphoma
10.1038/bjc.2012.380 · 2012 · External reference
Loss of assembly of the main basement membrane collagen, type IV, but not fibril-forming collagens and embryonic death in collagen prolyl 4-hydroxylase I null mice
10.1074/jbc.m606608200 · 2007 · External reference
Knockdown of P4HA1 inhibits neovascularization via targeting glioma stem cell-endothelial cell transdifferentiation and disrupting vascular basement membrane
10.18632/oncotarget.16270 · 2017 · External reference
The effects of knockdown of wild-type survivin, survivin-2B or survivin-delta3 on the radiosensitization in a soft tissue sarcoma cells in vitro under different oxygen conditions
10.1038/sj.cgt.7701090 · 2007 · External reference
Normoxic accumulation of HIF1alpha is associated with glutaminolysis
10.1007/s00784-016-1780-9 · 2017 · External reference
Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) Method
10.1006/meth.2001.1262 · 2001 · External reference
A novel splice variant of the stem cell marker LGR5/GPR49 is correlated with the risk of tumor-related death in soft-tissue sarcoma patients
10.1186/1471-2407-11-429 · 2011 · External reference
Osteopontin and splice variant expression level in human malignant glioma: radiobiologic effects and prognosis after radiotherapy
10.1016/j.radonc.2013.06.036 · 2013 · External reference
Hypoxia in cancer: significance and impact on clinical outcome
10.1007/s10555-007-9055-1 · 2007 · External reference
Detection and specific targeting of hypoxic regions within solid tumors: current preclinical and clinical strategies
10.2174/092986708783497391 · 2008 · External reference
Hypoxic induction of Prolyl 4-hydroxylase alpha (I) in cultured cells
10.1074/jbc.275.19.14139 · 2000 · External reference
Oxygen tension regulates the expression of a group of procollagen hydroxylases
10.1046/j.1432-1033.2003.03846.x · 2003 · External reference
Regulation of type II collagen synthesis during osteoarthritis by prolyl-4-hydroxylases: possible influence of low oxygen levels
10.2353/ajpath.2006.050738 · 2006 · External reference
Collagen prolyl hydroxylases are essential for breast cancer metastasis
10.1158/0008-5472.can-12-3963 · 2013 · External reference
The E2F transcription factors regulate tumor development and metastasis in a mouse model of metastatic breast cancer
10.1128/mcb.00737-14 · 2014 · External reference
Hypoxic control of metastasis
10.1126/science.aaf4405 · 2016 · External reference
Involvement of members of the cadherin superfamily in cancer
10.1101/cshperspect.a003129 · 2009 · External reference
The R-spondin/Lgr5/Rnf43 module: regulator of Wnt signal strength
10.1101/gad.235473.113 · 2014 · External reference
Mechanisms of TGFbeta-induced epithelial-mesenchymal transition
10.3390/jcm5070063 · 2016 · External reference
An autocrine TGF-beta/ZEB/miR-200 signaling network regulates establishment and maintenance of epithelial-mesenchymal transition
10.1091/mbc.e11-02-0103 · 2011 · External reference
Epithelial-to-mesenchymal transition and cancer stem(-like) cells in head and neck squamous cell carcinoma
10.1016/j.canlet.2012.06.013 · 2013 · External reference
