Research graph
References from Reirradiation of recurrent brain tumors: a review by the ESTRO CNS Focus Group. Local targets link to admitted publications; unresolved targets remain external evidence.
The evolving role of reirradiation in the management of recurrent brain tumors
10.1007/s11060-023-04407-2 · 2023 · External reference
Reirradiation Collaborative Group (ReCOG) consensus on standards for dose evaluation and reporting in patients with multiple courses of radiation therapy: an AAPM/ACRO/ASTRO/CARO/COMP/CADRA/CPQR/ESTRO/NRG-endorsed consensus statement
10.1016/s1470-2045(25)00562-5 · 2026 · External reference
European Society for Radiotherapy and Oncology and European Organisation for Research and Treatment of Cancer consensus on re-irradiation: definition, reporting, and clinical decision making
10.1016/s1470-2045(22)00447-8 · 2022 · External reference
Reirradiation: standards, challenges, and patient-focused strategies across tumor types
2025 · External reference
Clinical outcomes of recurrent intracranial meningiomas treated with proton beam reirradiation
10.14338/ijpt-18-00045.1 · 2019 · External reference
Re-irradiation of recurrent gliomas: pooled analysis and validation of an established prognostic score—report of the Radiation Oncology Group of the German Cancer Consortium
10.1002/cam4.1425 · 2018 · External reference
Patterns of care in primary brain tumour reirradiation: a survey by the ESTRO CNS focus group
10.1016/j.radonc.2025.111299 · 2026 · External reference
Radiation dose–volume effects of optic nerves and chiasm
10.1016/j.ijrobp.2009.07.1753 · 2010 · External reference
Radiotherapy for the treatment of pituitary adenomas: a dosimetric comparison of three planning techniques
10.1016/j.rpor.2020.04.020 · 2020 · External reference
Single- and multi-fraction stereotactic radiosurgery dose tolerances of the optic pathways
10.1016/j.ijrobp.2018.01.053 · 2021 · External reference
ESTRO/EANO recommendation on reirradiation of glioblastoma
10.1016/j.radonc.2024.110696 · 2025 · External reference
Clinical efficacy of adjuvant radiotherapy for World Health Organization grade II intracranial meningioma
10.1016/j.wneu.2023.04.075 · 2023 · External reference
Meningioma pathology and radiotherapy at initial diagnosis
2024 · External reference
Re-irradiation for recurrent intracranial meningiomas: analysis of clinical outcomes and prognostic factors
10.1016/j.radonc.2024.110271 · 2024 · External reference
Radiation therapy for meningiomas – where do we stand and what’s on the horizon?
10.1016/j.ijrobp.2024.10.034 · 2025 · External reference
Rinse and repeat? The role of reirradiation in meningiomas – a systematic review and meta-analysis
10.1016/j.adro.2026.102077 · 2026 · External reference
EANO guideline on the diagnosis and management of meningiomas
10.1093/neuonc/noab150 · 2021 · External reference
Dose fractionation in stereotactic radiotherapy for parasellar meningiomas: radiobiological considerations of efficacy and optic nerve tolerance
10.3171/sup.2004.101.supplement3.0390 · 2004 · External reference
Dosimetric comparison of protons vs photons in re-irradiation of intracranial meningioma
10.1259/bjr.20190113 · 2019 · External reference
Reirradiation of recurrent meningioma
10.1016/j.jocn.2012.01.023 · 2012 · External reference
Analysis of the results of recurrent intracranial meningiomas treated with re-radiosurgery
10.1016/j.clineuro.2016.12.014 · 2017 · External reference
Radiologic response and disease control of recurrent intracranial meningiomas treated with reirradiation
10.1016/j.ijrobp.2018.05.011 · 2018 · External reference
Re-irradiation of anaplastic meningioma: higher dose and concomitant bevacizumab may improve progression-free survival
10.1186/s13014-024-02486-7 · 2024 · External reference
Salvage stereotactic radiosurgery for recurrent WHO grade 2 and 3 meningiomas: a multicenter study (STORM)
10.1016/j.ijrobp.2024.04.016 · 2024 · External reference
Evaluation of particle radiotherapy for the re-irradiation of recurrent intracranial meningioma
10.1186/s13014-018-1026-x · 2018 · External reference
Targeted gene expression profiling predicts meningioma outcomes and radiotherapy responses
10.1038/s41591-023-02586-z · 2023 · External reference
A framework for using DNA methylation-based modelling for the clinical management of cranial meningioma
10.1093/neuonc/noaf237 · 2026 · External reference
EANO guidelines for the diagnosis and treatment of ependymal tumors
10.1093/neuonc/nox166 · 2018 · External reference
Ependymoma: evaluation and management updates
10.1007/s11912-022-01260-w · 2022 · External reference
A retrospective study of surgery and reirradiation for recurrent ependymoma
10.1016/j.ijrobp.2007.09.037 · 2008 · External reference
Re-irradiation of locally recurrent pediatric intracranial ependymoma: experience of the French society of children’s cancer
10.1016/j.radonc.2018.11.009 · 2019 · External reference
Extent of re-excision, sequence/timing of salvage re-irradiation, and disease-free interval impact upon clinical outcomes in recurrent/progressive ependymoma
10.1007/s11060-020-03434-7 · 2020 · External reference
Outcomes after reirradiation for recurrent Pediatric intracranial ependymoma
10.1016/j.ijrobp.2017.10.002 · 2018 · External reference
Re-irradiation of recurrent anaplastic ependymoma using radiosurgery or fractionated stereotactic radiotherapy
10.1007/s11604-015-0511-5 · 2016 · External reference
Stereotactic radiosurgery for ependymoma in Pediatric and adult patients: a single-institution experience
10.1227/neu.0000000000002979 · 2024 · External reference
Use of proton therapy for re-irradiation in pediatric intracranial ependymoma
10.1016/j.radonc.2015.07.023 · 2015 · External reference
Multidisciplinary management strategies for recurrent brain metastasis after prior radiotherapy: an overview
10.1093/neuonc/noae220 · 2025 · External reference
Response assessment criteria for brain metastases: proposal from the RANO group
10.1016/s1470-2045(15)70057-4 · 2015 · External reference
Diagnostic performance of PET and perfusion-weighted imaging in differentiating tumor recurrence or progression from radiation necrosis in posttreatment gliomas: a review of literature
2020 · External reference
Contrast-enhanced perfusion MR imaging to differentiate between recurrent/residual brain neoplasms and radiation necrosis
2018 · External reference
Repeat stereotactic radiosurgery for locally recurrent brain metastases previously treated with stereotactic radiosurgery: a systematic review and meta-analysis of efficacy and safety
2022 · External reference
Re-resection of brain metastases – outcomes of an institutional cohort study and literature review
10.1186/s12885-025-13677-0 · 2025 · External reference
Salvage resection of recurrent previously irradiated brain metastases: tumor control and radiation necrosis dependency on adjuvant re-irradiation
10.1007/s11060-021-03872-x · 2021 · External reference
Genomic characterization of brain metastases reveals branched evolution and potential therapeutic targets
10.1158/2159-8290.cd-15-0369 · 2015 · External reference
Resistance mechanisms to targeted therapies in ROS1 + and ALK + non–small cell lung cancer
10.1158/1078-0432.ccr-17-2452 · 2018 · External reference
Single dose radiosurgical treatment of recurrent previously irradiated primary brain tumors and brain metastases: final report of RTOG protocol 90-05
10.1016/s0360-3016(99)00507-6 · 2000 · External reference
Repeated stereotactic radiosurgery for patients with progressive brain metastases
10.1007/s11060-015-1937-4 · 2016 · External reference
Hypofractionated stereotactic radiosurgery (HSRS) as a salvage treatment for brain metastases failing prior stereotactic radiosurgery (SRS)
10.1007/s11060-023-04265-y · 2023 · External reference
Salvage radiosurgery for brain metastases: prognostic factors to consider in patient selection
10.1016/j.ijrobp.2013.10.003 · 2014 · External reference
Re-whole brain radiotherapy may be one of the treatment choices for symptomatic brain metastases patients
10.3390/cancers14215293 · 2022 · External reference
Repeated courses of radiosurgery for new brain metastases to defer whole brain radiotherapy: feasibility and outcome with validation of the new prognostic metric brain metastasis velocity
10.3389/fonc.2018.00551 · 2018 · External reference
Acute toxicities and cumulative dose to the brain of repeated sessions of stereotactic radiotherapy (SRT) for brain metastases: a retrospective study of 184 patients
10.1186/s13014-022-02194-0 · 2023 · External reference
Overview of the 2022 WHO classification of pituitary tumors
10.1007/s12022-022-09703-7 · 2022 · External reference
CBTRUS statistical report: primary brain and other central nervous system tumors diagnosed in the United States in 2018–2022
10.1093/neuonc/noaf194 · 2025 · External reference
Stereotactic radiosurgery for non-functioning pituitary adenomas: meta-analysis and International stereotactic radiosurgery society practice opinion
10.1093/neuonc/noz225 · 2020 · External reference
Current perspectives on recurrent pituitary adenoma: the role and timing of surgery vs adjuvant treatment
10.1111/cen.14127 · 2020 · External reference
Long-term tumor control following repeat gamma-knife radiosurgery of growing pituitary adenomas: a population-based cohort study
10.1007/s00701-024-06341-2 · 2024 · External reference
Characteristic of tumor regrowth after gamma knife radiosurgery and outcomes of repeat gamma knife radiosurgery in nonfunctioning pituitary adenomas
2021 · External reference
Stereotactic radiotherapy and radiosurgery for non-functioning and secreting pituitary adenomas
10.1016/j.rpor.2014.09.004 · 2016 · External reference
Stereotactic radiosurgery for acromegaly: an international Multicenter retrospective cohort study
10.1093/neuros/nyy178 · 2019 · External reference
Long-term results of hypofractionated stereotactic radiotherapy with CyberKnife for growth hormone-secreting pituitary adenoma: evaluation by the Cortina consensus
10.1007/s11060-016-2105-1 · 2016 · External reference
Results of gamma knife surgery for Cushing’s disease
10.3171/2013.7.jns13217 · 2013 · External reference
Efficacy and safety of higher dose stereotactic radiosurgery for functional pituitary adenomas: a preliminary report
10.1016/j.wneu.2013.01.127 · 2014 · External reference
Gamma knife radiosurgery as a primary treatment for prolactinomas
10.3171/jns.2000.93.supplement_3.0010 · 2000 · External reference
Risk factor analysis and prediction model to establish recurrence or progression of non-functioning pituitary adenomas in men after transnasal sphenoidal surgery
10.1038/s41598-024-72944-5 · 2024 · External reference
Natural history of postoperative nonfunctioning pituitary adenomas: a systematic review and meta-analysis
10.1159/000339823 · 2012 · External reference
Factors predicting relapse of nonfunctioning pituitary macroadenomas after neurosurgery: a study of 142 patients
10.1530/eje-10-0255 · 2010 · External reference
10.1111/j.1365-2265.2009.03583.x
10.1111/j.1365-2265.2009.03583.x · External reference
Stereotactic reirradiation with temozolomide in patients with recurrent aggressive pituitary tumors and pituitary carcinomas
10.1007/s11060-020-03579-5 · 2020 · External reference
Feasibility and outcome of re-irradiation in the treatment of multiply recurrent pituitary adenomas
10.1007/s11102-013-0541-x · 2014 · External reference
Radiation-induced hypopituitarism after cancer therapy: who, how and when to test
10.1038/ncpendmet1051 · 2009 · External reference
Examination of the dose-effect relationship of radiation-induced hypopituitarism: results of a case-control study
2021 · External reference
Adrenocorticotropic hormone secreting pituitary carcinoma: rare, durable response to concurrent chemotherapy and reirradiation with a review of the literature
2022 · External reference
Proton therapy for brain tumours in the area of evidence-based medicine
10.1259/bjr.20190237 · 2020 · External reference
DEGRO practical guideline for central nervous system radiation necrosis part 2: treatment
10.1007/s00066-022-01973-8 · 2022 · External reference
Association between radiation necrosis and tumor biology after stereotactic radiosurgery for brain metastasis
10.1016/j.ijrobp.2016.08.039 · 2016 · External reference
The European association for neuro-oncology (EANO) consensus statement on radiation necrosis
10.1093/neuonc/noag153 · 2026 · External reference
The dilemma of radiation necrosis from diagnosis to treatment in the management of brain metastases
10.1093/neuonc/noad188 · 2024 · External reference
Decoding patient heterogeneity influencing radiation-induced brain necrosis
10.1158/1078-0432.ccr-24-1215 · 2024 · External reference
Increased relative biological effectiveness and periventricular radiosensitivity in proton therapy of glioma patients
10.1016/j.radonc.2022.11.011 · 2023 · External reference
A mechanistic model of brain necrosis progression based on vascular heterogeneity
10.1016/j.ijrobp.2025.09.059 · 2026 · External reference
Current status and recent advances in reirradiation of glioblastoma
10.1186/s13014-021-01767-9 · 2021 · External reference
Stereotactic radiosurgery for brain metastases: analysis of outcome and risk of brain radionecrosis
10.1186/1748-717x-6-48 · 2011 · External reference
Single- and multifraction stereotactic radiosurgery dose/volume tolerances of the brain
10.1016/j.ijrobp.2020.08.013 · 2021 · External reference
Dose-volume tolerance of the brain and predictors of radiation necrosis after 3-fraction radiosurgery for brain metastases: a large single-institutional analysis
10.1016/j.ijrobp.2023.07.040 · 2024 · External reference
Hypofractionated stereotactic radiation therapy for intact brain metastases in 5 daily fractions: effect of dose on treatment response
10.1016/j.ijrobp.2021.09.003 · 2022 · External reference
Factors associated with radiation necrosis and intracranial control in patients treated with immune checkpoint inhibitors and stereotactic radiotherapy
10.1016/j.radonc.2023.109920 · 2023 · External reference
ESMO–ESTRO consensus statements on the safety of combining radiotherapy with immune checkpoint inhibitors, VEGF(R) inhibitors, or multitargeted tyrosine kinase inhibitors
10.1016/j.annonc.2025.09.008 · 2026 · External reference
High-dose re-irradiation of intracranial lesions – efficacy and safety including dosimetric analysis based on accumulated EQD2Gy dose calculation
2021 · External reference
Controversies in neuro-oncology: focal proton versus photon radiation therapy for adult brain tumors
10.1093/nop/npae040 · 2024 · External reference
Robust proton treatment planning: physical and biological optimization
10.1016/j.semradonc.2017.11.005 · 2018 · External reference
Differentiating tumor recurrence from treatment necrosis: a review of neuro-oncologic imaging strategies
10.1093/neuonc/nos307 · 2013 · External reference
Updated response assessment criteria for high-grade gliomas: response assessment in neuro-oncology working group
10.1200/jco.2009.26.3541 · 2010 · External reference
RANO 2.0: critical updates and practical considerations for radiological assessment in neuro-oncology
10.1007/s11604-025-01821-6 · 2025 · External reference
EANO guidelines on the diagnosis and treatment of diffuse gliomas of adulthood
10.1038/s41571-020-00447-z · 2021 · External reference
Current emerging MRI tools for radionecrosis and pseudoprogression diagnosis
10.1097/cco.0000000000000793 · 2021 · External reference
10.3174/ajnr.a1377
10.3174/ajnr.a1377 · 2009 · External reference
Relative cerebral blood volume is a potential biomarker in late delayed radiation-induced brain injury
10.1002/jmri.25837 · 2018 · External reference
Utility of dynamic susceptibility contrast perfusion-weighted MR imaging and 11 C-methionine PET/CT for differentiation of tumor recurrence from radiation injury in patients with high-grade gliomas
10.3174/ajnr.a5952 · 2019 · External reference
Amino acid PET in Neurooncology
10.2967/jnumed.122.264859 · 2023 · External reference
Contrast clearance analysis in neuro-oncology: a systematic review and meta-analysis on differentiating posttreatment changes from tumor progression
2025 · External reference
A systematic review informing the management of symptomatic brain radiation necrosis after stereotactic radiosurgery and international stereotactic radiosurgery society recommendations
10.1016/j.ijrobp.2023.07.015 · 2024 · External reference
Randomized double-blind placebo-controlled trial of bevacizumab therapy for radiation necrosis of the central nervous system
10.1016/j.ijrobp.2009.12.061 · 2011 · External reference
Boswellia serrata for the Management of Radiation-Induced Cerebral Edema and Necrosis: a systematic Meta-narrative review of clinical evidence
2025 · External reference
Boswellia serrata acts on cerebral edema in patients irradiated for brain tumors
10.1002/cncr.25945 · 2011 · External reference
Boswellia Serrata for cerebral radiation necrosis after radiosurgery for brain metastases
10.1016/j.ijrobp.2025.02.016 · 2025 · External reference
Laser interstitial thermal therapy (LITT) vs. bevacizumab for radiation necrosis in previously irradiated brain metastases
10.1007/s11060-020-03570-0 · 2020 · External reference
Hyperbaric oxygen therapy as an alternative therapeutic option for radiation-induced necrosis following radiotherapy for intracranial pathologies
10.1016/j.wneu.2024.01.161 · 2024 · External reference
