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References from Circadian control of dopaminergic signaling to the mushroom body regulates sleep through rhythmic Pka-C1 transcription in Drosophila. Local targets link to admitted publications; unresolved targets remain external evidence.
Circadian rhythms: Implications for health and disease
10.1016/j.ncl.2019.04.004 · 2019 · External reference
Animal sleep: A review of sleep duration across phylogeny
10.1016/0149-7634(84)90054-x · 1984 · External reference
Identification of a circadian output circuit for rest:activity rhythms in Drosophila
10.1016/j.cell.2014.02.024 · 2014 · External reference
Evaluating the Adaptive Fitness of Circadian Clocks and their Evolution
10.1177/07487304231219206 · 2024 · External reference
Circadian clock-independent ultradian rhythms in lipid metabolism in the Drosophila fat body
10.1016/j.jbc.2025.110245 · 2025 · External reference
Setting the clock - By nature: Circadian rhythm in the fruitfly Drosophila melanogaster
10.1016/j.febslet.2011.02.028 · 2011 · External reference
The adaptive value of circadian clocks: An experimental assessment in cyanobacteria
10.1016/j.cub.2004.08.023 · 2004 · External reference
The intertwined relationship between circadian dysfunction and Parkinson’s disease
10.1016/j.tins.2024.10.006 · 2025 · External reference
Circadian clock dysfunction and psychiatric disease: Could fruit flies have a say?
10.3389/fneur.2015.00080 · 2015 · External reference
Circadian organization of behavior and physiology in Drosophila
10.1146/annurev-physiol-021909-135815 · 2010 · External reference
Novel Insights into the Regulation of the Timeless Protein
10.1523/jneurosci.23-21-07810.2003 · 2003 · External reference
Restoration of circadian behavioural rhythms by gene transfer in Drosophila
10.1038/312752a0 · 1984 · External reference
Molecular genetics of a biological clock in Drosophila
10.1073/pnas.81.7.2142 · 1984 · External reference
VRILLE Feeds Back to Control Circadian Transcription of Clock in the Drosophila Circadian Oscillator
10.1016/s0896-6273(03)00002-3 · 2003 · External reference
Molecular analysis of the period locus in Drosophila melanogaster and identification of a transcript involved in biological rhythms
10.1016/0092-8674(84)90265-4 · 1984 · External reference
Genetics and molecular biology of rhythms in Drosophila and other insects
10.1016/s0065-2660(03)48000-0 · 2003 · External reference
Synaptic connectome of the Drosophila circadian clock
10.1038/s41467-024-54694-0 · 2024 · External reference
The circadian system: Plasticity at many levels
10.1016/j.neuroscience.2013.05.036 · 2013 · External reference
Two clocks in the brain: An update of the morning and evening oscillator model in Drosophila
10.1016/b978-0-444-59427-3.00027-7 · 2012 · External reference
Adult-Specific Electrical Silencing of Pacemaker Neurons Uncouples Molecular Clock from Circadian Outputs
10.1016/j.cub.2011.09.027 · 2011 · External reference
Circadian and feeding cues integrate to drive rhythms of physiology in Drosophila insulin-producing cells
10.1101/gad.288258.116 · 2016 · External reference
Regulation of gustatory physiology and appetitive behavior by the Drosophila circadian clock
10.1016/j.cub.2009.12.055 · 2010 · External reference
The clock gene period differentially regulates sleep and memory in Drosophila
10.1016/j.nlm.2018.02.016 · 2018 · External reference
A critical period of sleep for development of courtship circuitry and behavior in Drosophila
10.1126/science.1250553 · 2014 · External reference
Sleep in Drosophila is regulated by adult mushroom bodies
10.1038/nature04811 · 2006 · External reference
The Drosophila Mushroom Body: From Architecture to Algorithm in a Learning Circuit
10.1146/annurev-neuro-080317-0621333 · 2020 · External reference
Coordinated and Compartmentalized Neuromodulation Shapes Sensory Processing in Drosophila
10.1016/j.cell.2015.11.019 · 2015 · External reference
Representations of Novelty and Familiarity in a Mushroom Body Compartment
10.1016/j.cell.2017.04.028 · 2017 · External reference
Activity of Defined Mushroom Body Output Neurons Underlies Learned Olfactory Behavior in Drosophila
10.1016/j.neuron.2015.03.025 · 2015 · External reference
A neural circuit linking learning and sleep in Drosophila long-term memory
10.1038/s41467-022-28256-1 · 2022 · External reference
Mushroom body output neurons encode valence and guide memory-based action selection in Drosophila
10.7554/elife.04580 · 2014 · External reference
The neuronal architecture of the mushroom body provides a logic for associative learning
10.7554/elife.04577 · 2014 · External reference
The making of the Drosophila mushroom body
10.3389/fphys.2023.1091248 · 2023 · External reference
The connectome of the adult Drosophila mushroom body provides insights into function
10.7554/elife.62576 · 2020 · External reference
Compartment specific regulation of sleep by mushroom body requires GABA and dopaminergic signaling
10.1038/s41598-021-99531-2 · 2021 · External reference
Eight Different Types of Dopaminergic Neurons Innervate the Drosophila Mushroom Body Neuropil: Anatomical and Physiological Heterogeneity
10.3389/neuro.04.005.2009 · 2009 · External reference
D1 Dopamine Receptor dDA1 Is Required in the Mushroom Body Neurons for Aversive and Appetitive Learning in Drosophila
10.1523/jneurosci.1167-07.2007 · 2007 · External reference
Dopaminergic neurons write and update memories with cell-type-specific rules
10.7554/elife.16135 · 2016 · External reference
Distinct dopamine receptor pathways underlie the temporal sensitivity of associative learning
10.1016/j.cell.2019.05.040 · 2019 · External reference
Dopaminergic systems create reward seeking despite adverse consequences
10.1038/s41586-023-06671-8 · 2023 · External reference
Dopamine and Octopamine Differentiate between Aversive and Appetitive Olfactory Memories in Drosophila
10.1523/jneurosci.23-33-10495.2003 · 2003 · External reference
Distinct dopamine neurons mediate reward signals for short- and long-term memories
10.1073/pnas.1421930112 · 2015 · External reference
Dopamine is a regulator of arousal in the fruit fly
10.1523/jneurosci.2048-05.2005 · 2005 · External reference
Dopamine modulation of sensory processing and adaptive behavior in flies
10.1007/s00441-020-03371-x · 2021 · External reference
Neurofibromin 1 in mushroom body neurons mediates circadian wake drive through activating cAMP-PKA signaling
10.1038/s41467-021-26031-2 · 2021 · External reference
Emerging roles for microRNA in the regulation of Drosophila circadian clock
10.1186/s12868-018-0401-8 · 2018 · External reference
Circadian regulation of a limited set of conserved microRNAs in Drosophila
10.1186/1471-2164-9-83 · 2008 · External reference
The mushroom body of adult Drosophila characterized by GAL4 drivers
10.1080/01677060802471718 · 2009 · External reference
A Single-Cell Transcriptome Atlas of the Aging Drosophila Brain
10.1016/j.cell.2018.05.057 · 2018 · External reference
Fly Cell Atlas: A single-nucleus transcriptomic atlas of the adult fruit fly
10.1126/science.abk2432 · 2022 · External reference
Homeostatic maintenance and age-related functional decline in the Drosophila ear
10.1038/s41598-020-64498-z · 2020 · External reference
Onecut1 Is Essential for Horizontal Cell Genesis and Retinal Integrity
10.1523/jneurosci.0116-13.2013 · 2013 · External reference
The Clock:Cycle complex is a major transcriptional regulator of Drosophila photoreceptors that protects the eye from retinal degeneration and oxidative stress
10.1371/journal.pgen.1010021 · 2022 · External reference
The Drosophila homolog of Onecut homeodomain proteins is a neural-specific transcriptional activator with a potential role in regulating neural differentiation
10.1016/s0925-4773(00)00431-7 · 2000 · External reference
Circadian clock disruption promotes the degeneration of dopaminergic neurons in male Drosophila
10.1038/s41467-023-41540-y · 2023 · External reference
retro-Tango enables versatile retrograde circuit tracing in Drosophila
10.7554/elife.85041 · 2023 · External reference
Whole-brain annotation and multi-connectome cell typing of Drosophila
10.1038/s41586-024-07686-5 · 2024 · External reference
Neuroanatomical details of the lateral neurons of Drosophila melanogaster support their functional role in the circadian system
10.1002/cne.24406 · 2018 · External reference
Transcriptional regulation via nuclear receptor crosstalk required for the drosophila circadian clock
10.1016/j.cub.2015.04.017 · 2015 · External reference
Mapping neural circuits with activity-dependent nuclear import of a transcription factor
10.3109/01677063.2011.642910 · 2012 · External reference
Synchronous Drosophila circadian pacemakers display non-synchronous Ca2+ rhythms in vivo
10.1126/science.aad3997 · 2016 · External reference
Morning and Evening Circadian Pacemakers Independently Drive Premotor Centers via a Specific Dopamine Relay
10.1016/j.neuron.2019.03.028 · 2019 · External reference
Cloning and Functional Characterization of a Novel Dopamine Receptor from Drosophila melanogaster
10.1523/jneurosci.16-12-03925.1996 · 1996 · External reference
Primary structure and functional characterization of a Drosophila dopamine receptor with high homology to human D1/5 receptors
1994 · External reference
A primordial dopamine D1-like adenylyl cyclase-linked receptor from Drosophila melanogaster displaying poor affinity for benzazepines
10.1016/0014-5793(95)00224-w · 1995 · External reference
A Drosophila dopamine 2-like receptor: Molecular characterization and identification of multiple alternatively spliced variants
10.1073/pnas.202498299 · 2002 · External reference
Neural Control of Startle-Induced Locomotion by the Mushroom Bodies and Associated Neurons in Drosophila
10.3389/fnsys.2018.00006 · 2018 · External reference
Protein kinase A phosphorylates hepatocyte nuclear factor-6 and stimulates glucose-6-phosphatase catalytic subunit gene transcription
10.1074/jbc.m101442200 · 2001 · External reference
The Drosophila circuitry of sleep–wake regulation
10.1016/j.conb.2017.03.004 · 2017 · External reference
Characterization of a functional neuropeptide F receptor from Drosophila melanogaster
10.1016/s0196-9781(01)00647-7 · 2002 · External reference
Neuropeptide F regulates courtship in Drosophila through a male-specific neuronal circuit
10.7554/elife.49574 · 2019 · External reference
Short neuropeptide F is a sleep-promoting inhibitory modulator
10.1016/j.neuron.2013.07.029 · 2013 · External reference
Drosophila Neuropeptide F Signaling Independently Regulates Feeding and Sleep-Wake Behavior
10.1016/j.celrep.2017.05.085 · 2017 · External reference
Temperature cues are integrated in a flexible circadian neuropeptidergic feedback circuit to remodel sleep-wake patterns in flies
10.1371/journal.pbio.3002918 · 2024 · External reference
A two-process model of Drosophila sleep reveals an inter-dependence between circadian clock speed and the rate of sleep pressure decay
10.1093/sleep/zsad277 · 2024 · External reference
Gamma neurons mediate dopaminergic input during aversive olfactory memory formation in Drosophila
10.1016/j.cub.2012.02.014 · 2012 · External reference
Fly Memory: A Mushroom Body Story in Parts
10.1016/j.cub.2009.07.064 · 2009 · External reference
Localization of a short-term memory in Drosophila
10.1126/science.288.5466.672 · 2000 · External reference
Temporal dynamics of neuronal activation by Channelrhodopsin-2 and TRPA1 determine behavioral output in Drosophila larvae
10.1152/jn.00071.2009 · 2009 · External reference
Morning and evening peaks of activity rely on different clock neurons of the Drosophila brain
10.1038/nature02935 · 2004 · External reference
Gal4 in the Drosophila female germline
10.1016/s0925-4773(98)00157-9 · 1998 · External reference
Exploiting position effects and the gypsy retrovirus insulator to engineer precisely expressed transgenes
10.1038/ng.101 · 2008 · External reference
Unresolved reference
External reference
Neuronal wiring diagram of an adult brain
10.1038/s41586-024-07558-y · 2024 · External reference
Highly specific and efficient CRISPR/Cas9-catalyzed homology-directed repair in Drosophila
10.1534/genetics.113.160713 · 2014 · External reference
neuPrint: An open access tool for EM connectomics
10.3389/fninf.2022.896292 · 2022 · External reference
Fiji – an Open platform for biological image analysis
2009 · External reference
Analysis of Sleep and Circadian Rhythms from Drosophila Activity-Monitoring Data Using SCAMP
10.1101/pdb.prot108182 · 2024 · External reference
Methods for Detecting PER2:LUCIFERASE Bioluminescence Rhythms in Freely Moving Mice
10.1177/07487304211062829 · 2022 · External reference
Wavelet-based time series analysis of circadian rhythms
10.1177/0748730411416330 · 2011 · External reference
Analysis of Nonstationary Time Series for Biological Rhythms Research
10.1177/0748730417709105 · 2017 · External reference
Drosophila clock cells use multiple mechanisms to transmit time-of-day signals in the brain
10.1073/pnas.2019826118 · 2021 · External reference
Analysis of functional neuronal connectivity in the Drosophila brain
10.1152/jn.00110.2012 · 2012 · External reference
ChIPping Away at the Drosophila Clock
10.1016/bs.mie.2014.10.019 · 2015 · External reference
Correlates of sleep and waking in Drosophila melanogaster
10.1126/science.287.5459.1834 · 2000 · External reference
